Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Greta Tarlos"'
Autor:
Greta Tarlos, Laszlo Jozsef Szentpeteri, Sándor Balogh, Reka Varnai, István Szabó, Attila Sik, Csilla Sipeky
Publikováno v:
The Pharmacogenomics Journal
Pharmacogenomic biomarker availability of Hungarian Summaries of Product Characteristics (SmPC) was assembled and compared with the information in US Food and Drug Administration (FDA) drug labels of the same active substance (July 2019). The level o
Autor:
Reka Varnai, Petra Matyas, Béla Melegh, Renata Szalai, Greta Tarlos, István Szabó, Csilla Sipeky, Ingrid Janicsek, Alma Ganczer, Agnes Weber
Publikováno v:
Environmental Toxicology and Pharmacology. 40:280-283
Pharmacogenetic based dosing recommendations are provided in FDA-approved warfarin label for Caucasians. Evidence of notable difference in dosing algorithms of under-represented populations forced us to explore the genetic variability of CYP4F2 gene
Autor:
Greta Tarlos, Csilla Sipeky, Agnes Weber, Melinda Szabo, Ingrid Janicsek, Béla Melegh, István Szabó, Katalin Sumegi
Publikováno v:
Molecular Biology Reports. 40:4727-4735
The purpose of our study was to characterise the CYP2C19*2 and CYP2C19*3 alleles in healthy Roma and Hungarian populations. DNA of 500 Roma and 370 Hungarian subjects were genotyped for CYP2C19*2 (G681A, rs4244285) and CYP2C19*3 (G636A, rs4986893) by
Publikováno v:
Orvosi Hetilap. 153:191-194
Thiopurine s-methyltransferase enzyme is responsible for the metabolism of immunosuppressant thiopurines, which are used in inflammatory bowel diseases, acute lymphoblastic leukemia and autoimmune diseases. Because of the relative narrow therapeutic
Autor:
Reka Varnai, Alma Ganczer, Ingrid Janicsek, Marton Melegh, Petra Matyas, Renata Szalai, Béla Melegh, Csilla Sipeky, Greta Tarlos, István Szabó
Publikováno v:
Molecular biology reports. 41(9)
The purpose of this work was to characterise the W24X mutation of the GJB2 gene in order to provide more representative and geographicaly relevant carrier rates of healthy Roma subisolates and the Hungarian population. 493 Roma and 498 Hungarian heal