Výsledky vyhledávání - "Greta Pessino"

Akademický článek

Differential effect of asparagine and glutamine removal on three adenocarcinoma cell lines

Autor: Greta Pessino, Leonardo Lonati, Claudia Scotti, Silvia Calandra, Ornella Cazzalini, Ombretta Iaria, Andrea Previtali, Giorgio Baiocco, Paola Perucca, Anna Tricarico, Martina Vetro, Lucia Anna Stivala, Carlo Ganini, Marta Cancelliere, Massimo Zucchetti, Isabella Guardamagna, Maristella Maggi

Publikováno v: Heliyon, Vol 10, Iss 15, Pp e35789- (2024)

Asparagine and glutamine depletion operated by the drug Asparaginase (ASNase) has revolutionized therapy in pediatric patients affected by Acute Lymphoblastic Leukemia (ALL), bringing remissions to a remarkable 90 % of cases. However, the knowledge o

Externí odkaz: https://doaj.org/article/8328c688f1b84c4c9e71693bf28ebd4c

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Akademický článek

MICA/B-targeted antibody promotes NK cell–driven tumor immunity in patients with intrahepatic cholangiocarcinoma

Autor: Barbara Oliviero, Stefania Varchetta, Dalila Mele, Greta Pessino, Roberta Maiello, Monica Falleni, Delfina Tosi, Matteo Donadon, Cristiana Soldani, Barbara Franceschini, Guido Torzilli, Gaetano Piccolo, Matteo Barabino, Enrico Opocher, Marcello Maestri, Stefano Bernuzzi, Kai W. Wucherpfennig, Mario U. Mondelli, Stefania Mantovani

Publikováno v: OncoImmunology, Vol 11, Iss 1 (2022)

The major histocompatibility complex-class I chain related proteins A and B (MICA/B) is upregulated because of cellular stress and MICA/B shedding by cancer cells causes escape from NKG2D recognition favoring the emergence of cancers. Cholangiocarcin

Externí odkaz: https://doaj.org/article/5aa25f350bde4679a9569a19f98cfd67

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Akademický článek

Impaired intratumoral natural killer cell function in head and neck carcinoma

Autor: Dalila Mele, Greta Pessino, Giuseppe Trisolini, Alberto Luchena, Marco Benazzo, Patrizia Morbini, Stefania Mantovani, Barbara Oliviero, Mario U. Mondelli, Stefania Varchetta

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Natural killer (NK) cells are emerging as unique players in the immune response against cancer; however, only limited data are available on tumor infiltrating NK cells in head and neck squamous cell carcinoma (HNSCC), one of the most common cancer. O

Externí odkaz: https://doaj.org/article/d70106eab97546b0ba573cc4777af767

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Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line

Autor: Isabella Guardamagna, Ombretta Iaria, Leonardo Lonati, Alice Mentana, Andrea Previtali, Virginia Uggè, Giovanni Battista Ivaldi, Marco Liotta, Paola Tabarelli de Fatis, Claudia Scotti, Greta Pessino, Maristella Maggi, Giorgio Baiocco

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2983

Colorectal cancer (CRC) is the most prominent form of colon cancer for both incidence (38.7 per 100,000 people) and mortality (13.9 per 100,000 people). CRC’s poor response to standard therapies is linked to its high heterogeneity and complex genet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc22e0984b0a4669a6e804e5a3a3491

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A Targeted Catalytic Nanobody (T-CAN) with Asparaginolytic Activity

Autor: Isabella Guardamagna, Cristina Pulimeno, Greta Pessino, Maristella Maggi, Leonardo Lonati, Claudia Scotti

Publikováno v: Cancers, Vol 13, Iss 5637, p 5637 (2021)
Cancers
Volume 13
Issue 22

Simple Summary The therapy of Acute Lymphoblastic Leukemia (ALL) is based on Escherichia coli (E. coli) L-asparaginase, which is a very effective drug in most cases. However, its side effects sometimes prevent its usage or impose its interruption. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63b4beb67dfad22c48c9d401fef32a9
https://www.mdpi.com/2072-6694/13/22/5637

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Anti-Cancer Auto-Antibodies: Roles, Applications and Open Issues

Autor: Maristella Maggi, Hugo de Jonge, Luisa Iamele, Claudia Scotti, Greta Pessino

Publikováno v: Cancers
Cancers, Vol 13, Iss 813, p 813 (2021)

Simple Summary Cancer is one of the main causes of death worldwide and early detection is crucial for effective treatment. Scientists have therefore focused on the identification of circulating cancer-specific molecules, so-called markers, that can b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2407bd28ac1f54c4f2cbec9dbc1f200
http://europepmc.org/articles/PMC7919283

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