Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Greta M. Bauer"'
Autor:
Scott Gladstein, Luay M. Almassalha, Lusik Cherkezyan, John E. Chandler, Adam Eshein, Aya Eid, Di Zhang, Wenli Wu, Greta M. Bauer, Andrew D. Stephens, Simona Morochnik, Hariharan Subramanian, John F. Marko, Guillermo A. Ameer, Igal Szleifer, Vadim Backman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Methods to track molecular motion in eukaryotic cells mostly rely on fluorescent labels, transfection or photobleaching. Here the authors use multimodal partial wave spectroscopy to perform label-free live cell measurements of nanoscale structure and
Externí odkaz:
https://doaj.org/article/0c957e1c9b824bd39ac73359f6e497aa
Autor:
Ranya Virk, Jane Frederick, Luay M. Almassalha, Vasundhara Agrawal, Yue Li, Greta M. Bauer, Wenli Wu, Wing Shun Li, David VanDerway, Igal Szleifer, Vadim Backman
Publikováno v:
Biophysical Journal. 122:494a
Autor:
Greta M. Bauer, Aya Eid, John F. Marko, Luay M. Almassalha, Hariharan Subramanian, Simona Morochnik, Di Zhang, Wenli Wu, John E. Chandler, Guillermo A. Ameer, Scott Gladstein, Vadim Backman, Andrew D. Stephens, Igal Szleifer, Adam Eshein, Lusik Cherkezyan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Understanding the relationship between intracellular motion and macromolecular structure remains a challenge in biology. Macromolecular structures are assembled from numerous molecules, some of which cannot be labeled. Most techniques to study motion
Autor:
Nicholas M. Anthony, David VanDerway, Reiner Bleher, John E. Chandler, Adam Eshein, Anne R. Shim, Vadim Backman, Wenli Wu, Aya Eid, Surbhi Jain, Greta M. Bauer, Vinayak P. Dravid, Luay M. Almassalha, Igal Szleifer, The-Quyen Nguyen, Emily M. Pujadas, Vasundhara Agrawal, George Esteve, Yue Li, Kai Huang, Xiang Zhou, Juan J. de Pablo, Ranya Virk, Scott Gladstein, Jane Frederick
Publikováno v:
Science Advances
nano-ChIA combines multiple nanoimaging modalities to uncover 4D chromatin organization and its relationship to molecular function.
Extending across multiple length scales, dynamic chromatin structure is linked to transcription through the regul
Extending across multiple length scales, dynamic chromatin structure is linked to transcription through the regul
Autor:
Wenli Wu, Vadim Backman, Igal Szleifer, Vinayak P. Dravid, Kai Huang, Vasundhara Agrawal, The-Quyen Nguyen, Ranya Virk, Yue Li, Adam Eshein, Emily M. Pujadas, Juan J. de Pablo, Aya Eid, Xiang Zhou, Reiner Bleher, Luay M. Almassalha, Greta M. Bauer, Nick Anthony, Scott Gladstein, David VanDerway, Jane Frederick, John E. Chandler
In eukaryotic cells, chromatin structure is linked to transcription processes through the regulation of genome organization. Extending across multiple length-scales - from the nucleosome to higher-order three-dimensional structures - chromatin is a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b20f6b68ece369b07711d8e0dc12ca
Autor:
Ranya Virk, Vadim Backman, Jane Frederick, David VanDerway, Hemant K. Roy, Wenli Wu, Igal Szleifer, Greta M. Bauer, Adam Eshein, Luay M. Almassalha, Di Zhang, Yue Li
Publikováno v:
Science Advances
The CPMC model demonstrates the regulatory role of chromatin’s physical structure on transcription and phenotypic plasticity.
Three-dimensional supranucleosomal chromatin packing plays a profound role in modulating gene expression by regulatin
Three-dimensional supranucleosomal chromatin packing plays a profound role in modulating gene expression by regulatin
Autor:
Shohreh Shahabi, Vadim Backman, Di Zhang, Daniel D. Billadeau, Greta M. Bauer, Thomas V. O'Halloran, Igal Szleifer, Andrew P. Mazar, Hemant K. Roy, Wenli Wu, David VanDerway, Alexis Kendra, Lusik Cherkezyan, John E. Chandler, Luay M. Almassalha, Scott Gladstein, Andrey Ugolkov, Brandon Luke L. Seagle
Publikováno v:
Nature Biomedical Engineering. 1:902-913
Many human diseases result from the dysregulation of the complex interactions between tens to thousands of genes. However, approaches for the transcriptional modulation of many genes simultaneously in a predictive manner are lacking. Here, through th
Autor:
Greta M. Bauer, Jane Frederick, Wenli Wu, Igal Szleifer, David VanDerway, Adam Eshein, Vadim Backman, Ranya Virk, Di Zhang, Yue Li, Luay M. Almassalha
Publikováno v:
Biophysical Journal. 118:549a-550a
Autor:
Hemant K. Roy, Luay M. Almassalha, Igal Szleifer, Vadim Backman, John E. Chandler, Scott Gladstein, Greta M. Bauer
Publikováno v:
Cancer Research. 76:5605-5609
Results have historically shown a broad plasticity in the origin of tumors and their functions, with significant heterogeneity observed in both morphologies and functional capabilities. Largely unknown, however, are the mechanisms by which these vari
Autor:
Aya Eid, Simona Morochnik, Luay M. Almassalha, Vadim Backman, Hariharan Subramanian, Greta M. Bauer, John E. Chandler, Guillermo A. Ameer, Lusik Cherkezyan, Igal Szleifer, Adam Eshein, Andrew D. Stephens, Wenli Wu, Scott Gladstein, Di Zhang, John F. Marko
We present a multimodal label-free interferometric imaging platform for measuring intracellular nanoscale structure and macromolecular dynamics in living cells with a sensitivity to macromolecules as small as 20nm and millisecond temporal resolution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf7d56138255d78d5921ef55f5edfb8
https://doi.org/10.1101/428383
https://doi.org/10.1101/428383