Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Greta E. Weiss"'
Autor:
Greta E Weiss, Robert J Ragotte, Doris Quinkert, Amelia M Lias, Madeline G Dans, Coralie Boulet, Oliver Looker, Olivia D Ventura, Barnabas G Williams, Brendan S Crabb, Simon J Draper, Paul R Gilson
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011182 (2023)
The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is the current leading blood-stage malaria vaccine candidate. PfRH5 functions as part of the pentameric PCRCR complex containing PTRAMP, CSS, PfCyRPA and PfRIPR, all of which ar
Externí odkaz:
https://doaj.org/article/860d3157d96a47f895c9adb7940cc078
Autor:
Natalie A Counihan, Scott A Chisholm, Hayley E Bullen, Anubhav Srivastava, Paul R Sanders, Thorey K Jonsdottir, Greta E Weiss, Sreejoyee Ghosh, Brendan S Crabb, Darren J Creek, Paul R Gilson, Tania F de Koning-Ward
Publikováno v:
eLife, Vol 6 (2017)
Plasmodium falciparum parasites, the causative agents of malaria, modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and for removal of toxic waste. Here we investigate the contribution of the rhop
Externí odkaz:
https://doaj.org/article/97ed3bf0078b4d8eba8c42a7a6284862
Autor:
Brendan S. Crabb, Paul R. Gilson, Brad E. Sleebs, Greta E. Weiss, Madeline G Dans, Tania F. de Koning-Ward, Danny W. Wilson
Publikováno v:
International Journal for Parasitology. 50:235-252
With emerging resistance to frontline treatments, it is vital that new drugs are identified to target Plasmodium falciparum. One of the most critical processes during parasites asexual lifecycle is the invasion and subsequent egress of red blood cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddc2c6652049d1ad1132823a03cc4fb
https://doi.org/10.1016/j.ijpara.2020.01.002
https://doi.org/10.1016/j.ijpara.2020.01.002
Autor:
Wai-Hong Tham, Nicholas T Y Lim, Greta E Weiss, Sash Lopaticki, Brendan R E Ansell, Megan Bird, Isabelle Lucet, Dominique Dorin-Semblat, Christian Doerig, Paul R Gilson, Brendan S Crabb, Alan F Cowman
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005343 (2015)
The most severe form of malaria in humans is caused by the protozoan parasite Plasmodium falciparum. The invasive form of malaria parasites is termed a merozoite and it employs an array of parasite proteins that bind to the host cell to mediate invas
Externí odkaz:
https://doaj.org/article/3af963e0c0d0429f82cbd882ebbb1153
Autor:
Greta E Weiss, Paul R Gilson, Tana Taechalertpaisarn, Wai-Hong Tham, Nienke W M de Jong, Katherine L Harvey, Freya J I Fowkes, Paul N Barlow, Julian C Rayner, Gavin J Wright, Alan F Cowman, Brendan S Crabb
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004670 (2015)
During blood stage Plasmodium falciparum infection, merozoites invade uninfected erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand binding events. Understanding each element in this process increases the pot
Externí odkaz:
https://doaj.org/article/1a1fe246a3be48d4bf55ff5da97ff1d3
Autor:
Greta E Weiss, Eva H Clark, Shanping Li, Boubacar Traore, Kassoum Kayentao, Aissata Ongoiba, Jean N Hernandez, Ogobara K Doumbo, Susan K Pierce, OraLee H Branch, Peter D Crompton
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15983 (2011)
Antibodies that protect against Plasmodium falciparum (Pf) malaria are only acquired after years of repeated infections. The B cell biology that underlies this observation is poorly understood. We previously reported that "atypical" memory B cells ar
Externí odkaz:
https://doaj.org/article/8bb1e6d78c794f61b9c369515273bf51
Autor:
Greta E Weiss, Boubacar Traore, Kassoum Kayentao, Aissata Ongoiba, Safiatou Doumbo, Didier Doumtabe, Younoussou Kone, Seydou Dia, Agnes Guindo, Abdramane Traore, Chiung-Yu Huang, Kazutoyo Miura, Marko Mircetic, Shanping Li, Amy Baughman, David L Narum, Louis H Miller, Ogobara K Doumbo, Susan K Pierce, Peter D Crompton
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000912 (2010)
Immunity to Plasmodium falciparum (Pf) malaria is only acquired after years of repeated infections and wanes rapidly without ongoing parasite exposure. Antibodies are central to malaria immunity, yet little is known about the B-cell biology that unde
Externí odkaz:
https://doaj.org/article/739427abe8044433a5a44750bfd3fb56
Autor:
Danny W. Wilson, Paul R. Gilson, Greta E. Weiss, Tania F. de Koning-Ward, Madeline G Dans, Brendan S. Crabb, Brad E. Sleebs
To identify potential inhibitors of egress and invasion in the asexual blood stage of Plasmodium falciparum, we screened the Medicines for Malaria Venture (MMV) Pathogen Box. This compound library comprises of 400 drugs against neglected tropical dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7cf6edbd3c65436cbda2aefc4382bd
https://doi.org/10.1101/768648
https://doi.org/10.1101/768648
Publikováno v:
Trends in Parasitology. 32:284-295
A highly-effective, long-lasting vaccine, targeting multiple stages of the Plasmodium falciparum life cycle, is likely to be important for the elimination of this pathogen. Key antigens of this vaccine would produce host antibodies that block the lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276964a3a8928c349d5720609a6617e1
https://doi.org/10.1016/j.pt.2015.12.007
https://doi.org/10.1016/j.pt.2015.12.007
Autor:
Jennifer K. Thompson, Christoph Q. Schmidt, Paul N. Barlow, Alexander T. Kennedy, Paul R. Gilson, Brendan S. Crabb, Wai-Hong Tham, Greta E. Weiss, Alan F. Cowman, Tana Taechalertpaisarn
Publikováno v:
The Journal of Immunology. 196:1239-1248
The human complement system is the frontline defense mechanism against invading pathogens. The coexistence of humans and microbes throughout evolution has produced ingenious molecular mechanisms by which microorganisms escape complement attack. A com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7668776abaace9c59f85e98d8aa67ad
https://doi.org/10.4049/jimmunol.1501581
https://doi.org/10.4049/jimmunol.1501581