Immunological Dynamics Associated with Direct-Acting Antiviral Therapies in Naive and Experimented HCV Chronic-Infected Patients

Autor: Grenda Leite Pereira, Andréa Monteiro Tarragô, Walter Luiz Lima Neves, Pedro Vieira da Silva Neto, Priscila Sarmento de Souza, Juliana dos Santos Affonso, Keyla Santos de Sousa, Jéssica Albuquerque da Silva, Allyson Guimarães Costa, Flamir da Silva Victoria, Marilu Barbieri Victoria, Adriana Malheiro

Publikováno v: Mediators of Inflammation, Vol 2019 (2019)

The therapeutic strategies used in the treatment of hepatitis C are essentially based on the combination of direct-acting antiviral agents (DAAs). This therapy has been shown to be very effective in relation to patient adherence to treatment and has

Externí odkaz: https://doaj.org/article/313e10d7a2c2466baca70c2962c10288

Inflammasome genes polymorphisms may influence the development of hepatitis C in the Amazonas, Brazil

Autor: Nadja Pinto Garcia, Juliana dos Santos Affonso, Aya Sadahiro, Jéssica Albuquerque da Silva, Adriana Malheiro, Hanna Lara Silva Negreiros Dray, Rajendranath Ramasawmy, Mauricio Morishi Ogusku, Flamir da Silva Victoria, Diana Mota Toro, Grenda Leite Pereira, Pedro Vieira da Silva Neto, Allyson Guimarães Costa, Keyla Santos de Sousa, Marilú Victória Barbieri, Eduardo Antônio Donadi, Andréa Monteiro Tarragô, Priscila Santos Sarmento

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0253470 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Hepatitis C is considered a major public health problem caused by the hepatitis C virus (HCV). Viral infections are known to induce production of IL1β through the signaling pathway of inflammasomes. Emerging evidences suggest that Inflammasome genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5dfc2821e47290dee4b09b34682754c
http://europepmc.org/articles/PMC8221483

Combination of genetic polymorphisms in TLR influence cytokine profile in HCV patients treated with DAAs in the State of Amazonas

Autor: Flamir da Silva Victoria, Grenda Leite Pereira, Diana Mota Toro, Adriana Malheiro, Pedro Vieira da Silva Neto, Lilyane Amorim Xabregas, Rajendranath Ramasawmy, Andréa Monteiro Tarragô, Marilu Barbieri Victoria, Allyson Guimarães Costa

Publikováno v: Cytokine. 130:155052

Hepatitis C is a public health problem and affects approximately 3% of the world's population. HCV infections have a wide spectrum of clinical manifestations, and several single nucleotide polymorphisms (SNPs) in the genes of the toll-like receptors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bd46e31b0de6c2a8cfede95fbe7354
https://doi.org/10.1016/j.cyto.2020.155052