Výsledky vyhledávání - "Greice Kelle Viegas Saraiva"

Akademický článek

Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells

Autor: Arthur Cássio de Lima Luna, Greice Kelle Viegas Saraiva, Gilberto Orivaldo Chierice, Henrique Hesse, Durvanei Augusto Maria

Publikováno v: BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-14 (2018)

Abstract Background Current studies have demonstrated that DODAC/PHO-S (Dioctadecyldimethylammonium Chloride/Synthetic phosphoethanolamine) liposomes induces cytotoxicity in Hepa1c1c7 and B16F10 murine tumor cells, with a higher proportion than PHO-S

Externí odkaz: https://doaj.org/article/d5180a9d03d94b15a3cf8628f79be074

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Akademický článek

Naphthalimide-Containing BP100 Leads to Higher Model Membranes Interactions and Antimicrobial Activity

Autor: Gustavo Penteado Battesini Carretero, Greice Kelle Viegas Saraiva, Magali Aparecida Rodrigues, Sumika Kiyota, Marcelo Porto Bemquerer, Hernan Chaimovich, Iolanda Midea Cuccovia

Publikováno v: Biomolecules, Vol 11, Iss 4, p 542 (2021)

In a large variety of organisms, antimicrobial peptides (AMPs) are primary defenses against pathogens. BP100 (KKLFKKILKYL-NH2), a short, synthetic, cationic AMP, is active against bacteria and displays low toxicity towards eukaryotic cells. BP100 acq

Externí odkaz: https://doaj.org/article/c1a3ba403ca8481b9ad776d3dcf7d521

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Dissertation/ Thesis

Caracterização de copolímeros e efeito da estrutura em sistemas biomiméticos

Autor: Greice Kelle Viegas Saraiva

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

Copolímeros, macromoléculas orgânicas ou inorgânicas com alta massa molar, consistem de unidades monômericas repetidas, unidas por ligações covalentes e que apresentam mais de um tipo de monômero. Neste trabalho estudamos três copolímeros c

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/46/46131/tde-23092015-143832/

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Stimuli-responsive polymersomes of poly [2-(dimethylamino) ethyl methacrylate]-b-polystyrene

Autor: Gustavo P.B. Carretero, Valdomiro Vagner de Souza, Iris Todeschini, Fabio Herbst Florenzano, Iolanda M. Cuccovia, Greice Kelle Viegas Saraiva, Phelipe Augusto Mariano Vitale, Paloma O. Kotani, Cristiane R. Guzzo, Hernan Chaimovich

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Amphiphilic diblock copolymers may assemble in aqueous solutions to form vesicles delimited by a polymeric double layer, also known as polymersomes, considered a more robust option to liposomes. Diblock copolymers may respond to pH, temperature, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a83ae75d24081e29f9cca9161502273
https://doi.org/10.1007/s00289-020-03533-5

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Violacein Targets the Cytoplasmic Membrane of Bacteria

Autor: Greice Kelle Viegas Saraiva, Laura Mortara, Marcelo Brocchi, Ana C.G. Cauz, Iolanda M. Cuccovia, Peter Park, Frederico J. Gueiros-Filho, Gustavo P.B. Carretero

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Violacein is a tryptophan-derived purple pigment produced by environmental bacteria, which displays multiple biological activities, including strong inhibition of Gram-positive pathogens. Here, we applied a combination of experimental approaches to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9339c7ba7c1779bfe32eaa24c97700
https://doi.org/10.1021/acsinfecdis.8b00245

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Naphthalimide-containing BP100 leads to higher model membranes interactions and antimicrobial activity

Autor: Gustavo P.B. Carretero, Hernan Chaimovich, Sumika Kiyota, Magali A. Rodrigues, Greice Kelle Viegas Saraiva, Iolanda M. Cuccovia, Marcelo P. Bemquerer

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biomolecules
Volume 11
Issue 4
Biomolecules, Vol 11, Iss 542, p 542 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5771efea457b274efb6d62702cbb549

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Characterization of PMMA-b-PDMAEMA aggregates in aqueous solutions

Autor: Greice Kelle Viegas Saraiva, J. C. Masini, L. Coutinho de Oliveira, V. V. de Souza, Hernan Chaimovich, Fabio Herbst Florenzano, Roberto Kopke Salinas, Iolanda M. Cuccovia, M. L. C. Noronha

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Colloid and Polymer Science
Colloid and Polymer Science, Springer Verlag, 2019, 297 (4), pp.557-569. ⟨10.1007/s00396-019-04482-w⟩

International audience; Diblock amphiphilic copolymers form aggregates in some solvents. Such aggregates exhibit different morphologies, depending mainly on the polar/apolar block ratios. Aggregation of copolymers with polar block excess leads to mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dedfa5435f2744ee4f3566c1894535

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Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells

Autor: Gilberto Orivaldo Chierice, Greice Kelle Viegas Saraiva, Durvanei Augusto Maria, Henrique Hesse, Arthur Cássio de Lima Luna

Publikováno v: BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-14 (2018)

Background Current studies have demonstrated that DODAC/PHO-S (Dioctadecyldimethylammonium Chloride/Synthetic phosphoethanolamine) liposomes induces cytotoxicity in Hepa1c1c7 and B16F10 murine tumor cells, with a higher proportion than PHO-S. Therefo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb85eada0068661550e7f05886dc324
https://doi.org/10.1186/s40360-018-0225-2

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Synthesis, biophysical and functional studies of two BP100 analogues modified by a hydrophobic chain and a cyclic peptide

Autor: Frederico J. Gueiros-Filho, Marcelo P. Bemquerer, Gustavo P.B. Carretero, Magali A. Rodrigues, Sumika Kiyota, Hernan Chaimovich, Ana C.G. Cauz, Alcindo A. Dos Santos, Karin A. Riske, Greice Kelle Viegas Saraiva, Shirley Schreier, Marcos Felipe Pinatto-Botelho, Iolanda M. Cuccovia

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Antimicrobial peptides (AMPs) work as a primary defense against pathogenic microorganisms. BP100, (KKLFKKILKYL-NH2), a rationally designed short, highly cationic AMP, acts against many bacteria, displaying low toxicity to eukaryotic cells. Previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8d47e8840568fa25efd2ffe6ae4e72

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Peptide:lipid ratio and membrane surface charge determine the mechanism of action of the antimicrobial peptide BP100. Conformational and functional studies

Autor: Marcelo P. Bemquerer, Karin A. Riske, Greice Kelle Viegas Saraiva, Talita L. Santos, Katia Regina Perez, Ana P. Valente, Fabio C. L. Almeida, José Carlos Bozelli, Magali A. Rodrigues, Hernan Chaimovich, Mário José Politi, Shirley Schreier, Iolanda M. Cuccovia, Marcia A. da Silva, Mariana C. Manzini

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The cecropin-melittin hybrid antimicrobial peptide BP100 (H-KKLFKKILKYL-NH2) is selective for Gram-negative bacteria, negatively charged membranes, and weakly hemolytic. We studied BP100 conformational and functional properties upon interaction with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b119465013762baa797392ab36a2873
https://doi.org/10.1016/j.bbamem.2014.04.004

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