Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gregory Z. Ferl"'
Autor:
Gregory Z. Ferl, Kai H. Barck, Jasmine Patil, Skander Jemaa, Evelyn J. Malamut, Anthony Lima, Jason E. Long, Jason H. Cheng, Melissa R. Junttila, Richard A.D. Carano
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105712- (2022)
Summary: Here, we have developed an automated image processing algorithm for segmenting lungs and individual lung tumors in in vivo micro-computed tomography (micro-CT) scans of mouse models of non-small cell lung cancer and lung fibrosis. Over 3000
Externí odkaz:
https://doaj.org/article/067c962811db439da9d3f24eeac1f62b
Autor:
Hanine Rafidi, Sharmila Rajan, Konnie Urban, Whitney Shatz-Binder, Keliana Hui, Gregory Z. Ferl, Amrita V. Kamath, C. Andrew Boswell
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for biologic therapies and expanding the need to understand how various structural aspects affect their
Externí odkaz:
https://doaj.org/article/6c3322f467974ab2941978a377de89ce
Autor:
Johannes Riegler, Herman Gill, Annie Ogasawara, Maj Hedehus, Vincent Javinal, Jason Oeh, Gregory Z. Ferl, Jan Marik, Simon Williams, Deepak Sampath, Jill Schartner, Richard A.D. Carano
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 1036-1050 (2019)
Cancer immunotherapies have demonstrated durable responses in a range of different cancers. However, only a subset of patients responds to these therapies. We set out to test if non-invasive imaging of tumor perfusion and vascular inflammation may be
Externí odkaz:
https://doaj.org/article/741a375fc66146b38b3c4feb55c71ce8
Autor:
Gregory Z. Ferl
Publikováno v:
Journal of Statistical Software, Vol 44, Iss 03 (2011)
Numerical deconvolution is a powerful mathematical operation that can be used to extract the impulse response function of a linear, time-invariant system. We have found this method to be useful for preliminary analysis of dynamic contrast enhanced ma
Externí odkaz:
https://doaj.org/article/aebfb1fb05e6429f8254cc6a1e376e91
Autor:
C. Andrew Boswell, Jack D. Sadowsky, James Ernst, Shang-Fan Yu, Jeffrey Lau, Jason Ho, Sheila Ulufatu, Christopher W. Davies, James T. Koerber, Gregory Z. Ferl, Danielle Mandikian, Hanine Rafidi, Lidia Nazarova
Supplementary methods (S1-S4), Supplementary tables (1-4) and Supplementary Figures (1-5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fca89884112d3846ac463a7b3718266
https://doi.org/10.1158/1535-7163.22521745
https://doi.org/10.1158/1535-7163.22521745
Autor:
C. Andrew Boswell, Gregory Z. Ferl, Amrita V. Kamath, Shang-Fan Yu, Mary Ann T. Go, Christoph Spiess, T. Noelle Lombana, Sheila Ulufatu, Jason Ho, Alecia T. Dent, Anna King, Lauren N. Sermeño, Danielle Mandikian, Madeleine K. Ramos
Supplementary Data and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d20dbeeb5c28537bd9c83b666eae461
https://doi.org/10.1158/1535-7163.22520782.v1
https://doi.org/10.1158/1535-7163.22520782.v1
Autor:
C. Andrew Boswell, James T. Koerber, Amrita V. Kamath, Simon P. Williams, Lauren Sermeño, Shannon Stainton, Danielle Mandikian, Gregory Z. Ferl, Alberto Estevez, Hanine Rafidi
Supplementary information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c17ed013e530bfa711221509fa7caf
https://doi.org/10.1158/1535-7163.22521663.v1
https://doi.org/10.1158/1535-7163.22521663.v1
Data from Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics
Autor:
C. Andrew Boswell, James T. Koerber, Amrita V. Kamath, Simon P. Williams, Lauren Sermeño, Shannon Stainton, Danielle Mandikian, Gregory Z. Ferl, Alberto Estevez, Hanine Rafidi
Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for cancer immunotherapeutic drug discovery while also revealing limitations in knowledge of structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5892a7bbcb15fb55b8c79dd6e9f20c8b
https://doi.org/10.1158/1535-7163.c.6543102
https://doi.org/10.1158/1535-7163.c.6543102
Data from Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration
Autor:
C. Andrew Boswell, Gregory Z. Ferl, Amrita V. Kamath, Shang-Fan Yu, Mary Ann T. Go, Christoph Spiess, T. Noelle Lombana, Sheila Ulufatu, Jason Ho, Alecia T. Dent, Anna King, Lauren N. Sermeño, Danielle Mandikian, Madeleine K. Ramos
T-cell–dependent bispecific antibodies (TDB) have been a major advancement in the treatment of cancer, allowing for improved targeting and efficacy for large molecule therapeutics. TDBs are comprised of one arm targeting a surface antigen on a canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd688727755b297ffbdcffd11f0001e7
https://doi.org/10.1158/1535-7163.c.6542773
https://doi.org/10.1158/1535-7163.c.6542773
Supplementary Material from A two-tiered physiologically based model for dually labeled single-chain Fv-Fc antibody fragments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab95d41375f7438a6935e781db0b7cc
https://doi.org/10.1158/1535-7163.22487916
https://doi.org/10.1158/1535-7163.22487916