Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gregory Wurz"'
Autor:
Koester Sk, Valerie J. Wiebe, Michael W. DeGregorio, Juhani Maenpaa, Vernon Emshoff, Seymour Rc, Gregory Wurz
Publikováno v:
Cancer Chemotherapy and Pharmacology. 35:149-152
To study tamoxifen resistance-stimulated growth, 30 female ovariectomized nude mice were implanted with tamoxifen-resistant tumors and treated with 10-1000 micrograms/day of tamoxifen citrate subcutaneously. Tamoxifen stimulated MCF-7 tumor growth in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3712177d16bc0d345aebca7a100589
https://doi.org/10.1007/bf00686638
https://doi.org/10.1007/bf00686638
Autor:
Thomas P. Dooley, Pirkko Sipila, Gregory Wurz, Valerie J. Wiebe, Michael DeGregorio, Edward S. Robinson, Vernon Emshoff, Calvin L. Day, John L. VandeBerg, Juhani Maenpaa
Publikováno v:
Cancer Chemotherapy and Pharmacology. 32:392-395
The distribution of topically applied toremifene (0.5-1 mg/day for 5 days) in the ultraviolet B (UVB)-induced Monodelphis domestica opossum melanoma model was examined. The mean concentration of toremifene measured in the skin was 1200 nmol/g, or500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63059bf538389dd5f392886eb1f72439
https://doi.org/10.1007/bf00735925
https://doi.org/10.1007/bf00735925
Autor:
Valerie J. Wiebe, Koester Sk, Gregory Wurz, Baker Wj, Juhani Maenpaa, DeGregorio Mw, Vernon Emshoff
Publikováno v:
Breast Cancer Research and Treatment. 24:43-49
The clinical study of compounds that modulate multidrug resistance in cancer cells has been hindered by both the toxicities of these agents and the inability to monitor their effectiveness at a cellular level. The non-steroidal triphenylethylene tore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b31ce2ea6e683b0cb12c0c2c354689
https://doi.org/10.1007/bf01832357
https://doi.org/10.1007/bf01832357
Publikováno v:
Breast Cancer Research and Treatment. 24:35-41
Monitoring effective antiestrogenic activity of the triphenylethylenes in patients with breast cancer is usually determined by the duration of response. The pharmacokinetics of toremifene and tamoxifen have been shown to be highly variable but patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb57f3febb798bb1574795074ba6acea
https://doi.org/10.1007/bf01832356
https://doi.org/10.1007/bf01832356
Autor:
Baker Wj, Gregory Wurz, Koester Sk, Seymour Rc, Valerie J. Wiebe, Koehler Re, Juhani Maenpaa, DeGregorio Mw
Publikováno v:
Breast cancer research and treatment. 32(1)
Flow cytometric analysis of DNA ploidy and S-phase fraction are well recognized prognostic indicators in breast cancer. The present paper deals with the widening of the applications of flow cytometry to monitoring the effectiveness of antiestrogen th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a60d0e44227a5b814aa62c721df500
https://pubmed.ncbi.nlm.nih.gov/7819587
https://pubmed.ncbi.nlm.nih.gov/7819587
Publikováno v:
Cancer chemotherapy and pharmacology. 31(5)
Toremifene is currently being evaluated as a chemosensitizing agent in doxorubicin-resistant patients. Although concentrations of2 microM reverse resistance in vitro, target concentrations required to reverse multidrug resistance (MDR) in vivo may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d078a2e35d50ae6f71f790c84348fed0
https://pubmed.ncbi.nlm.nih.gov/8431976
https://pubmed.ncbi.nlm.nih.gov/8431976