Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Gregory Wulczyn"'
Autor:
Meng Xu, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P. Hoefig, Christine Hohn, Florian Giesert, Yinhu Wang, Wenliang Pan, Natalia Ziętara, Tobias Straub, Regina Feederle, Carolin Daniel, Barbara Adler, Julian König, Stefan Feske, George C. Tsokos, Wolfgang Wurst, Henning Urlaub, Michael Sattler, Jan Kisielow, F. Gregory Wulczyn, Marcin Łyszkiewicz, Vigo Heissmeyer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/9e89d380ba524171be8ac6b2c5c274ad
Autor:
Meng Xu, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P. Hoefig, Christine Hohn, Florian Giesert, Yinhu Wang, Wenliang Pan, Natalia Ziętara, Tobias Straub, Regina Feederle, Carolin Daniel, Barbara Adler, Julian König, Stefan Feske, George C. Tsokos, Wolfgang Wurst, Henning Urlaub, Michael Sattler, Jan Kisielow, F. Gregory Wulczyn, Marcin Łyszkiewicz, Vigo Heissmeyer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The regulation of thymocyte development by RNA-binding proteins (RBPs) is largely unexplored. We identify 642 RBPs in the thymus and focus on Arpp21, which shows selective and dynamic expression in early thymocytes. Arpp21 is downregulated i
Externí odkaz:
https://doaj.org/article/c1ccb1c3902a42deb7a8b59d19e9f6cb
Autor:
Frederick Rehfeld, Daniel Maticzka, Sabine Grosser, Pina Knauff, Murat Eravci, Imre Vida, Rolf Backofen, F. Gregory Wulczyn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Many microRNA encoding regions are within introns of other coding genes, and yet the molecular or functional interaction between the two is unclear. This study shows that miR-128′s function is opposed by its host gene ARPP21, and they have compleme
Externí odkaz:
https://doaj.org/article/7c8b8c16051e47579746c26c47d7c3ac
Autor:
Phan Q. Duy, Stefan C. Weise, Claudia Marini, Xiao-Jun Li, Dan Liang, Peter J. Dahl, Shaojie Ma, Ana Spajic, Weilai Dong, Jane Juusola, Emre Kiziltug, Adam J. Kundishora, Sunil Koundal, Maysam Z. Pedram, Lucia A. Torres-Fernández, Kristian Händler, Elena De Domenico, Matthias Becker, Thomas Ulas, Stefan A. Juranek, Elisa Cuevas, Le Thi Hao, Bettina Jux, André M. M. Sousa, Fuchen Liu, Suel-Kee Kim, Mingfeng Li, Yiying Yang, Yutaka Takeo, Alvaro Duque, Carol Nelson-Williams, Yonghyun Ha, Kartiga Selvaganesan, Stephanie M. Robert, Amrita K. Singh, Garrett Allington, Charuta G. Furey, Andrew T. Timberlake, Benjamin C. Reeves, Hannah Smith, Ashley Dunbar, Tyrone DeSpenza, June Goto, Arnaud Marlier, Andres Moreno-De-Luca, Xin Yu, William E. Butler, Bob S. Carter, Evelyn M. R. Lake, R. Todd Constable, Pasko Rakic, Haifan Lin, Engin Deniz, Helene Benveniste, Nikhil S. Malvankar, Juvianee I. Estrada-Veras, Christopher A. Walsh, Seth L. Alper, Joachim L. Schultze, Katrin Paeschke, Angelika Doetzlhofer, F. Gregory Wulczyn, Sheng Chih Jin, Richard P. Lifton, Nenad Sestan, Waldemar Kolanus, Kristopher T. Kahle
Publikováno v:
Nat Neurosci
Nature neuroscience 25(4), 458-473 (2022). doi:10.1038/s41593-022-01043-3
Nature neuroscience 25(4), 458-473 (2022). doi:10.1038/s41593-022-01043-3
Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the leading reason for brain surgery in children despite considerable d
Autor:
Eleonora Franzoni, Sam A Booker, Srinivas Parthasarathy, Frederick Rehfeld, Sabine Grosser, Swathi Srivatsa, Heiko R Fuchs, Victor Tarabykin, Imre Vida, F Gregory Wulczyn
Publikováno v:
eLife, Vol 4 (2015)
miR-128, a brain-enriched microRNA, has been implicated in the control of neurogenesis and synaptogenesis but its potential roles in intervening processes have not been addressed. We show that post-transcriptional mechanisms restrict miR-128 accumula
Externí odkaz:
https://doaj.org/article/62d4b7f06bb7475caf74488c33b3fa86
Autor:
F. Gregory Wulczyn, Claudia Marini, Carol Nelson-Williams, Daniel J. Foster, William J. Sullivan, Suel Kee Kim, Todd Constable, Elisa Cuevas, Richard P. Lifton, Waldemar Kolanus, June Goto, August A Allocco, Mingfeng Li, Charuta G. Furey, Yonghyun Ha, Le Hao, Xue Zeng, Sheng Chih Jin, Arnaud Marlier, Haifan Lin, Bettina Jux, Duy Phan, Amar H. Sheth, Yiying Yang, Evelyn Lake, Lucia A. Torres-Fernández, Weilai Dong, Frank J. Slack, Benjamin C. Reeves, Yutaka Takeo, André M. M. Sousa, Andres Moreno-De-Luca, Nenad Sestan, Stefan Weise, Tyrone DeSpenza, Fuchen Liu, Adam J. Kundishora, Ashley Dunbar, Benjamin C. Warf, Kristopher T. Kahle, Hannah Smith, Kartiga Selvaganesan, Seth L. Alper
Publikováno v:
Neurosurgery. 67
Autor:
David Kaul, Piet Habbel, Katja Derkow, Christina Krüger, Eleonora Franzoni, F Gregory Wulczyn, Stefan Bereswill, Robert Nitsch, Eckart Schott, Rüdiger Veh, Thomas Naumann, Seija Lehnardt
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37767 (2012)
Toll-like receptors (TLR) are key players of the innate and adaptive immune response in vertebrates. The original protein Toll in Drosophila melanogaster regulates both host defense and morphogenesis during development. Making use of real-time PCR, i
Externí odkaz:
https://doaj.org/article/858e25465c4a42df98fa9da369f1dc49
Autor:
Sibylle Mitschka, F. Gregory Wulczyn, Geert Michel, Duong Thi Thuy Nguyen, Waldemar Kolanus, Elisa Cuevas, Daniel Richter
Publikováno v:
Cell Death and Differentiation
Rapidity and specificity are characteristic features of proteolysis mediated by the ubiquitin-proteasome system. Therefore, the UPS is ideally suited for the remodeling of the embryonic stem cell proteome during the transition from pluripotent to dif
Publikováno v:
Cell and Tissue Research. 359:145-160
Beginning with their discovery in the context of stem cell fate choice in Caenorhabditis elegans, the microRNA (miRNA) let-7 and the RNA-binding protein Lin28 have been recognized as a regulatory pair with far-reaching impact on stem cell behavior in
Autor:
Douglas T. Golenbock, Seija Lehnardt, Michael Hinz, F. Gregory Wulczyn, Oliver Peters, David Kaul, Boyoun Park, Jan Baumgart, Agnieszka Rybak, Eleonora Franzoni, Eckart Schott, Thorsten Trimbuch, Katja Derkow, Duong T. T. Nguyen, Frank L. Heppner, Christina Krüger, Hidde L. Ploegh, Robert Nitsch, Gina D. Eom, Rüdiger W. Veh, Roland E. Kälin, Olaf Ninnemann, Piet Habbel, Sabrina M. Lehmann, Karen Rosenberger
Publikováno v:
Nature Neuroscience. 15:827-835
Activation of innate immune receptors by host-derived factors exacerbates CNS damage, but the identity of these factors remains elusive. We uncovered an unconventional role for the microRNA let-7, a highly abundant regulator of gene expression in the