Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gregory W.H. Wong"'
Autor:
Rudi Hwang, Albert H.C. Wong, Gwyneth Zai, Gregory W.H. Wong, Joseph Trakalo, Chima Matsumoto, Matthew B. Lanktree, Takahiro Shinkai, Osamu Ohmori, Fabio Macciardi, James L. Kennedy, Daniel J. Müller, Tricia Sicard, Jun Nakamura, Sajid A. Shaikh, Natalia Potapova, Nicole King, Vincenzo De Luca, Hiroko Hori
Publikováno v:
NeuroMolecular Medicine. 9:169-177
A number of linkage studies have previously implicated the region of chromosome 13q34 in schizophrenia. Chumakov and colleagues (2002) identified a gene complex called G72 (now termed D-amino acid oxidase activator: DAOA)/G30 in this region and perfo
Autor:
Vincenzo De Luca, Albert H.C. Wong, Livia Martucci, Gregory W.H. Wong, Nicole King, Olga Likhodi, James L. Kennedy
Publikováno v:
Schizophrenia Research. 84:214-221
The NR2B protein is a critical structural and functional subunit of the NMDA glutamate receptor. The glutamate neurotransmitter system has been implicated in psychosis and schizophrenia, and so we looked for genetic association and measured gene expr
Autor:
Karen Wigg, Gwyneth Zai, Gregory W.H. Wong, James L. Kennedy, Nicole King, Jillian M. Couto, Cathy L. Barr, William G. Honer
Publikováno v:
Genes, Brain and Behavior. 4:2-9
Schizophrenia (SCZ) is a neuropsychiatric disorder that affects approximately 1% of the general population. The human leukocyte antigen (HLA) system has been implicated in several genetic studies of SCZ. The myelin oligodendrocyte glycoprotein (MOG)
Autor:
Gregory W.H. Wong, Osamu Ohmori, Paul D. Arnold, Sajid A. Shaikh, Nicole King, James L. Kennedy, Takahiro Shinkai, Albert H.C. Wong, Gwyneth Zai, Natalia Potapova, Chima Matsumoto, Joseph Trakalo, Rudi Hwang, Jun Nakamura, Hiroko Hori, Vincenzo De Luca
Publikováno v:
Psychiatric Genetics. 14:177-180
Oxidative stress such as free radical-mediated neuronal dysfunction may be involved in the pathophysiology of schizophrenia. The human glutathione peroxidase (GPX1) is a selenium-dependent enzyme, which plays an important role in the detoxification o
Autor:
Gregory W.H. Wong, Albert H.C. Wong, Tasha Cate-Carter, Fabio Macciardi, Joseph Trakalo, Livia Martucci, James L. Kennedy
Publikováno v:
American Journal of Medical Genetics. :24-27
The N-methyl-d-aspartate glutamate receptors (NMDAR) act in the CNS as regulators of the release of neurotransmitters such as dopamine, noradrenaline, acetylcholine, and GABA. It has been suggested that a weakened glutamatergic tone increases the ris
Publikováno v:
Bipolar disorders. 9(5)
Background: Brain-derived neurotrophic factor (BDNF) plays an important role in the regulation of synaptic plasticity and neurotransmitter release across multiple neurotransmitter systems. Recent studies have suggested that BDNF plays a role in the p
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 15(3)
Schizophrenia (SCZ) is a severe neuropsychiatric disorder with a genetic component. The major inhibitory GABA-(gamma-aminobutyric acid) ergic system may be involved. The GABA type B receptor 1 (GABBR1) gene has been localized to 6p21.3, a region link
Autor:
James L. Kennedy, Takahiro Shinkai, Gregory W.H. Wong, Daphne Voineskos, John Strauss, Vincenzo De Luca, Claudia Rothe
Publikováno v:
Psychiatry research. 134(2)
Allele and haplotype frequencies of a promoter polymorphism in the gene encoding tryptophan hydroxylase (TPH2) did not differ in 83 suicidal schizophrenic patients compared with 170 non-suicidal schizophrenic patients. These findings suggest that the
Autor:
Vincenzo De Luca, James L. Kennedy, Rachel F. Tyndale, Gregory W.H. Wong, Albert H.C. Wong, Daniel J. Müller
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 29(8)
A number of studies have suggested that the alpha-7-nicotinic receptor D15S1360 polymorphism is associated with schizophrenia and a deficiency in the normal inhibition of the P50 auditory-evoked response. Schizophrenia patients and some of their unaf