Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gregory W. Henkel"'
Publikováno v:
International Immunology. 14:723-732
The requirement of the transcription factor PU.1 for macrophage development has been well documented. However, the target genes regulated by PU.1 controlling macrophage maturation are not known. A granulocyte macrophage colony stimulating factor (GM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad9642a4a052fd4fdc7433074502dcf
https://doi.org/10.1093/intimm/dxf040
https://doi.org/10.1093/intimm/dxf040
Publikováno v:
Journal of Leukocyte Biology. 66:727-732
PU.1 is a transcription factor shown to regulate the expression of many important genes in myeloid and B cells. At birth, mice homozygous for the disruption of the PU.1 gene have erythrocytes, megakaryocytes, and T cells, but no mature myeloid or B c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83311da98e6c02ea163d3086353e59d7
https://doi.org/10.1002/jlb.66.5.727
https://doi.org/10.1002/jlb.66.5.727
Autor:
Agnieszka M. Lichanska, Michael C. Ostrowski, Richard A. Maki, Catherine M. Browne, Gregory W. Henkel, David A. Hume, Kathleen M. Murphy, Scott R. McKercher
Publikováno v:
Blood. 94:127-138
During mouse embryogenesis, macrophage-like cells arise first in the yolk sac and are produced subsequently in the liver. The onset of liver hematopoiesis is associated with the transition from primitive to definitive erythrocyte production. This rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d50884cd83a3beb8076e429436b295
https://doi.org/10.1182/blood.v94.1.127.413k07_127_138
https://doi.org/10.1182/blood.v94.1.127.413k07_127_138
Publikováno v:
Blood, 93(9), 2849-2858. American Society of Hematology
Mice homozygous for the disruption of the PU.1 (Spi-1) gene do not produce mature macrophages. In determining the role of PU.1 in macrophage differentiation, the present study investigated whether or not there was commitment to the monocytic lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a25182f91c7572ce6fd3e136f04a02
https://doi.org/10.1182/blood.v93.9.2849
https://doi.org/10.1182/blood.v93.9.2849
Autor:
Zena Werb, Margaret L. Flannery, Hideyuki Yamamoto, Richard A. Maki, Gregory W. Henkel, Scott R. McKercher, Sergey Kupriyanov, Jonathan Pearce, Robert G. Oshima
Publikováno v:
Genes & Development. 12:1315-1326
Members of the Ets family of transcription factors mediate transcriptional responses of multiple signaling pathways in diverse cell types and organisms. Targeted deletion of the conserved DNA binding domain of the Ets2 transcription factor results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400c116e3e09f341f983035367d31554
https://doi.org/10.1101/gad.12.9.1315
https://doi.org/10.1101/gad.12.9.1315
Autor:
Richard A. Maki, Scott R. McKercher, Gregory W. Henkel, Robert G. Oshima, Karen L. Anderson, Hideyuki Yamamoto
Publikováno v:
Blood. 88:2917-2926
Transcription factors play an important role choreographing lineage commitment and expansion of blood cells. Nuclear factors that are expressed primarily or exclusively in hematopoietic cells are likely candidates for regulating blood cell developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00eec3a2a234045feb25c9814f3bc2e6
https://doi.org/10.1182/blood.v88.8.2917.bloodjournal8882917
https://doi.org/10.1182/blood.v88.8.2917.bloodjournal8882917
Autor:
Deborah J. Vestal, Bruce E. Torbett, Gillian E. Wu, Karen L. Anderson, Scott R. McKercher, Gregory W. Henkel, Helene Baribault, Christopher J. Paige, Richard A. Maki, Michael J. Klemsz, Ann J. Feeney
Publikováno v:
The EMBO Journal. 15:5647-5658
PU.1 is a member of the ets family of transcription factors and is expressed exclusively in cells of the hematopoietic lineage. Mice homozygous for a disruption in the PU.1 DNA binding domain are born alive but die of severe septicemia within 48 h. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae73f34901c48709b7503327bcd081d8
https://doi.org/10.1002/j.1460-2075.1996.tb00949.x
https://doi.org/10.1002/j.1460-2075.1996.tb00949.x