Zobrazeno 1 - 2
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pro vyhledávání: '"Gregory Vernier"'
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6280 (2009)
BACKGROUND:A key step of anthrax toxin action involves the formation of a protein-translocating pore within the endosomal membrane by the Protective Antigen (PA) moiety. Formation of this transmembrane pore by PA involves interaction of the seven 2be
Externí odkaz:
https://doaj.org/article/155069fcd9784fab87d4fdbffb325f85
Publikováno v:
The Journal of biological chemistry. 282(2)
Protective antigen (PA), the receptor-binding component of anthrax toxin, heptamerizes and inserts into the endosomal membrane at acidic pH, forming a pore that mediates translocation of the enzymic components of the toxin to the cytosol. When the he