Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gregory V. Carr"'
Autor:
Fan Mei, Chen Zhao, Shangjin Li, Zeping Xue, Yueyang Zhao, Yihua Xu, Rongrong Ye, He You, Peng Yu, Xinyu Han, Gregory V. Carr, Daniel R. Weinberger, Feng Yang, Bai Lu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Acetylcholine regulates various cognitive functions through broad cholinergic innervation. However, specific cholinergic subpopulations, circuits and molecular mechanisms underlying recognition memory remain largely unknown. Here we show tha
Externí odkaz:
https://doaj.org/article/0c6a03ec0d1e47a99e582c679076466b
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Effort-related choice (ERC) tasks allow animals to choose between high-value reinforcers that require high effort to obtain and low-value/low-effort reinforcers. Dopaminergic neuromodulation regulates ERC behavior. The enzyme catechol-O-methyltransfe
Externí odkaz:
https://doaj.org/article/14f74712b1f94013be2cac3abfff26a9
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Pharmacological studies indicate that dopamine D1-like receptors (D1 and D5) are critically involved in cognitive function. However, the lack of pharmacological ligands selective for either the D1 or D5 receptors has made it difficult to determine th
Externí odkaz:
https://doaj.org/article/b465d6eb2f7b463aab046742367717e3
Autor:
Alexander Shaver, J.D. Mahlum, Karen Scida, Melanie L. Johnston, Miguel Aller Pellitero, Yao Wu, Gregory V. Carr, Netzahualcóyotl Arroyo-Currás
Publikováno v:
ACS Sensors. 7:3895-3905
The measurement of serum vancomycin levels at the clinic is critical to optimizing dosing given the narrow therapeutic window of this antibiotic. Current approaches to quantitate serum vancomycin levels are based on immunoassays, which are multistep
Autor:
Henry L. Hallock, Suhaas Adiraju, Jorge Miranda-Barrientos, Jessica M. McInerney, Seyun Oh, Adrienne C. DeBrosse, Ye Li, Gregory V. Carr, Keri Martinowich
Publikováno v:
bioRxiv
Sustained attention, the ability to focus on an activity or stimulus over time, is significantly impaired in many psychiatric disorders, and there remains a major unmet need in treating impaired attention. Continuous performance tests (CPTs) were dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb3173db6601ca9b7d92a3658d28e8c
https://europepmc.org/articles/PMC10153204/
https://europepmc.org/articles/PMC10153204/
Publikováno v:
The FASEB Journal. 36
Autor:
Ingrid P. Buchler, Michael Wormald, Gangling Liao, Michael DePasquale, Huijun Wei, James C. Barrow, Gregory V. Carr, Gongliang Zhang
Publikováno v:
ACS Chemical Neuroscience
The male rat adrenal pheochromocytoma cell-derived PC12 cell line can synthesize and release catecholamine neurotransmitters, and it has been widely used as a model system in cell biology and toxicology research. Catechol-O-methyltransferase (COMT) i
Publikováno v:
Brain Research. 1712:151-157
The vesicular monoamine transporter is involved in presynaptic catecholamine storage and neurotransmission. Two isoforms of the transporter exist, VMAT1 and VMAT2, and both are expressed in the brain, though VMAT2 expression is more robust and has be
Autor:
Michael Noback, Keri Martinowich, Henry M. Quillian, Adrienne DeBrosse, Henry L. Hallock, Jessica Valerino, James C. Barrow, Gregory V. Carr, Andrew E. Jaffe
Publikováno v:
Biological Psychiatry. 89:S115-S116
Autor:
Gongliang Zhang, Gregory V. Carr, Spencer Byers, Michael DePasquale, Gangling Liao, Ingrid P. Buchler, Yupin Su, Huijun Wei, James C. Barrow
Publikováno v:
Eur J Pharmacol
Impaired dopamine activity in the dorsolateral prefrontal cortex (DLPFC) is thought to contribute to cognitive deficits in diseases such as schizophrenia, attention deficit hyperactivity disorder (ADHD) and traumatic brain injury. Catechol-O-methyltr