Výsledky vyhledávání - "Gregory Tudor"

Akademický článek

Evolving from Morbidity and Mortality to a Case-based Error Reduction Conference: Evidence-based Best Practices from the Council of Emergency Medicine Residency Directors

Autor: Yashwant Chathampally, Benjamin Cooper, David B. Wood, Gregory Tudor, Michael Gottlieb

Publikováno v: Western Journal of Emergency Medicine, Vol 21, Iss 6 (2020)

Morbidity and mortality conferences are common among emergency medicine residency programs and are an important part of quality improvement initiatives. Here we review the key components of running an effective morbidity and mortality conference with

Externí odkaz: https://doaj.org/article/de966ce0b5dd404f99a8e50ff2da09c3

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Evaluation of Plasma Biomarker Utility for the Gastrointestinal Acute Radiation Syndrome in Non-human Primates after Partial Body Irradiation with Minimal Bone Marrow Sparing through Correlation with Tissue and Histological Analyses

Autor: Gregory Tudor, Praveen Kumar, Ann M. Farese, Maureen A. Kane, Pengcheng Wang, Thomas J. MacVittie, Catherine Booth

Publikováno v: Health Phys

Exposure to total- and partial-body irradiation following a nuclear or radiological incident result in the potentially lethal acute radiation syndromes of the gastrointestinal and hematopoietic systems in a dose-and time-dependent manner. Radiation-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc9e5a32330f5da46ab453add382201
https://doi.org/10.1097/hp.0000000000001348

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Targeted Metabolomics Reveals Metabolomic Signatures Correlating Gastrointestinal Tissue to Plasma in a Mouse Total-body Irradiation Model

Autor: Fei Li, Maureen A. Kane, Ann M. Farese, Gregory Tudor, Catherine Booth, Jace W. Jones, Zachary Clifford, Thomas J. MacVittie

Publikováno v: Health Physics. 116:473-483

High-throughput, targeted metabolomics was used to identify early time point small intestine and plasma metabolite markers of gastrointestinal acute radiation syndrome. The small intestine metabolite markers were cross-correlated to plasma metabolite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697447f7ba21db310df17271a34955e0
https://doi.org/10.1097/hp.0000000000000955

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Proteomic Evaluation of the Acute Radiation Syndrome of the Gastrointestinal Tract in a Murine Total-body Irradiation Model

Autor: Keely Pierzchalski, Catherine Booth, Maureen A. Kane, Gregory Tudor, Jianshi Yu, Weiliang Huang, Claire L. Carter, Thomas J. MacVittie, Jace W. Jones

Publikováno v: Health Physics. 116:516-528

Radiation exposure to the gastrointestinal system contributes to the acute radiation syndrome in a dose- and time-dependent manner. Molecular mechanisms that lead to the gastrointestinal acute radiation syndrome remain incompletely understood. Using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae43f41d9a55abf3d46a9f6d50dd051b
https://doi.org/10.1097/hp.0000000000000951

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Characterizing the Natural History of Acute Radiation Syndrome of the Gastrointestinal Tract: Combining High Mass and Spatial Resolution Using MALDI-FTICR-MSI

Autor: Catherine Booth, Jace W. Jones, Kim G. Hankey, Thomas J. MacVittie, Ann M. Farese, Maureen A. Kane, Gregory Tudor, George A. Parker, Claire L. Carter

Publikováno v: Health Physics. 116:454-472

The acute radiation syndrome of the gastrointestinal tract has been histologically characterized, but the molecular and functional mechanisms that lead to these cellular alterations remain enigmatic. Mass spectrometry imaging is the only technique th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1f1292755910fba7ea2888633bac69
https://doi.org/10.1097/hp.0000000000000948

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The Gastrointestinal Subsyndrome of the Acute Radiation Syndrome in Rhesus Macaques: A Systematic Review of the Lethal Dose-response Relationship With and Without Medical Management

Autor: Ann M. Farese, Catherine Booth, Christopher S Potten, George A. Parker, Thomas J. MacVittie, Kim G. Hankey, Gregory Tudor, William E. Jackson

Publikováno v: Health Phys

Well-characterized animal models that mimic the human response to potentially lethal doses of radiation are required to assess the efficacy of medical countermeasures under the criteria of the Food and Drug Administration “animal rule”. Developme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834db0a41ebbfaff40a66e12f666aa1b
https://doi.org/10.1097/hp.0000000000000903

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Histopathological Features of the Development of Intestine and Mesenteric Lymph Node Injury in a Nonhuman Primate Model of Partial-body Irradiation with Minimal Bone Marrow Sparing

Autor: Ann M. Farese, Kyle Takayama, Gregory Tudor, Catherine Booth, George A. Parker, Na Li, Thomas J. MacVittie

Publikováno v: Health Physics. 116:426-446

Male rhesus macaques were subjected to partial-body irradiation at 10, 11, or 12 Gy with 5% bone marrow protection. Animals were euthanized when dictated by prospectively determined clinical parameters, or at approximately 180 days following irradiat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13e4bf5493451b9e1c83561130264f0
https://doi.org/10.1097/hp.0000000000000932

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Establishing Pediatric Mouse Models of the Hematopoietic Acute Radiation Syndrome and the Delayed Effects of Acute Radiation Exposure

Autor: Hailin Feng, P. Artur Plett, Hui Lin Chua, Catherine Booth, Gregory Tudor, Carol H. Sampson, Alexa Fisher, Rajendran Sellamuthu, Andrea M. Patterson, Thomas J. MacVittie, Barry P. Katz, Christie M. Orschell, Steven J. Miller, Sasidhar Vemula

Publikováno v: Radiation research. 195(4)

Medical countermeasures (MCMs) for hematopoietic acute radiation syndrome (H-ARS) should be evaluated in well-characterized animal models, with consideration of at-risk populations such as pediatrics. We have developed pediatric mouse models of H-ARS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d00d0458a938c09909646cac501b46
https://pubmed.ncbi.nlm.nih.gov/33577641

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Abstract C062: The use of nanoparticles to improve tumour radiosensitivity

Autor: Matt Stock, Ben Reed, Gareth Wakefield, Gregory Tudor

Publikováno v: Molecular Cancer Therapeutics. 18:C062-C062

Fractionated radiotherapy, administered by high energy external beam X-rays, is the mainstay of several cancer treatment regimens. However, treatment is often required for several weeks, with cure rates limited by radio-resistant hypoxic areas within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d3613d38c756d878cc300c69a912044
https://doi.org/10.1158/1535-7163.targ-19-c062

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