Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Gregory T. Reeves"'
Autor:
Razeen Shaikh, Nissa J. Larson, Jayden Kam, Donny Hanjaya-Putra, Jeremiah Zartman, David M. Umulis, Linlin Li, Gregory T. Reeves
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Throughout development, complex networks of cell signaling pathways drive cellular decision-making across different tissues and contexts. The transforming growth factor β (TGF-β) pathways, including the BMP/Smad pathway, play crucial roles
Externí odkaz:
https://doaj.org/article/3669c29368d94780b7de6129a992a379
Autor:
Hadel Al Asafen, Aydin Beseli, Hung-Yuan Chen, Sharva Hiremath, Cranos M. Williams, Gregory T. Reeves
Publikováno v:
Biology Open, Vol 13, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/2b798c8737c84ff18db1eeb5387015c8
Autor:
Gregory T. Reeves
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-11 (2019)
Abstract Background Regulation of gene expression is of paramount importance in all living systems. In the past two decades, it has been discovered that certain motifs, such as the feedforward motif, are overrepresented in gene regulatory circuits. F
Externí odkaz:
https://doaj.org/article/66523abff21f43e098fbc4953e30ab49
Autor:
Hadel Al Asafen, Prasad U Bandodkar, Sophia Carrell-Noel, Allison E Schloop, Jeramey Friedman, Gregory T Reeves
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007750 (2020)
In multicellular organisms, the timing and placement of gene expression in a developing tissue assigns the fate of each cell in the embryo in order for a uniform field of cells to differentiate into a reproducible pattern of organs and tissues. This
Externí odkaz:
https://doaj.org/article/d5b80327cede47099d0f744282889b99
Autor:
Thomas Jacobsen, Gloria Yi, Hadel Al Asafen, Ashley A Jermusyk, Chase L Beisel, Gregory T Reeves
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232046 (2020)
Advancements in the field of synthetic biology have been possible due to the development of genetic tools that are able to regulate gene expression. However, the current toolbox of gene regulatory tools for eukaryotic systems have been outpaced by th
Externí odkaz:
https://doaj.org/article/189166a4f6f946448f7a817bc1207913
Model development is essential to gain a mathematical understanding of the underlying phenomena in systems biology. In most models, it is typically hard to estimate the values of the biophysical/phenomenological parameters that characterize the model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5507dea19954c36dae05812a1299dc1e
https://doi.org/10.1101/2023.04.29.538818
https://doi.org/10.1101/2023.04.29.538818
In developing tissues, morphogen gradients are thought to initialize gene expression patterns. However, the relationship between the dynamics of morphogen-encoded signals and gene expression decisions are largely unknown. Here we examine the dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7fed3a188f2ce6bae0927d712829a44
https://doi.org/10.1101/2022.10.20.513072
https://doi.org/10.1101/2022.10.20.513072
Autor:
Sophia Carrell-Noel, Jeramey Friedman, Alexander D. Thomas, Allison E. Schloop, Gregory T. Reeves
Publikováno v:
Dev Biol
In a developing animal, morphogen gradients act to pattern tissues into distinct domains of cell types. However, despite their prevalence in development, morphogen gradient formation is a matter of debate. In our recent publication, we showed that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d81ad467db91a99df24ba19eda95fb
https://doi.org/10.1016/j.ydbio.2020.01.011
https://doi.org/10.1016/j.ydbio.2020.01.011
The use of immunodetection assays including the widely used enzyme-linked immunosorbent assay (ELISA) in applications such as point-of-care detection is often limited by the need for protein immobilization and multiple binding and washing steps. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbea921e466154af58939241ce36436
https://doi.org/10.1101/2022.02.13.480265
https://doi.org/10.1101/2022.02.13.480265
Autor:
Michael D O'Connell, Gregory T Reeves
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 4, p e1004159 (2015)
In a developing embryo, the spatial distribution of a signaling molecule, or a morphogen gradient, has been hypothesized to carry positional information to pattern tissues. Recent measurements of morphogen distribution have allowed us to subject this
Externí odkaz:
https://doaj.org/article/195f0452daa449618153000076c00254