Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gregory Severson"'
Autor:
Yan Chen, Erin Kwang, Rachel E. Johns, Renata Fam, Michael McCutcheon, Feng Chen, Alan So, Gregory Severson, Barry Polisky, Michael V. Templin, Yoshiyuki Matsui, Roger C. Adami, Tod Brown, Kathy Fosnaugh, Iwona M. Maciagiewicz, Pierrot Harvie, Yan Liu, Shaguna Seth, Akihide Takagi, Narendra K. Vaish, Tianying Zhu, Susan Bell, Ken Farber, Michael E. Houston, Patrick Charmley
Publikováno v:
Molecular Therapy. 19(5):928-935
Harnessing RNA interference (RNAi) to silence aberrant gene expression is an emerging approach in cancer therapy. Selective inhibition of an overexpressed gene via RNAi requires a highly efficacious, target-specific short interfering RNA (siRNA) and
Autor:
Michael E. Houston, Brian R. Granger, Yan Liu, Gregory Severson, Shaguna Seth, Barry Polisky, Roger C. Adami, Rachel E. Johns, Feng Chen, Patrick Charmley, Pierrot Harvie, Tod Brown, Kathy Fosnaugh, Narendra K. Vaish, Michael V. Templin, Yan Chen
Publikováno v:
Nucleic Acids Research
siRNAs confer sequence specific and robust silencing of mRNA. By virtue of these properties, siRNAs have become therapeutic candidates for disease intervention. However, their use as therapeutic agents can be hampered by unintended off-target effects
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 623
RNA interference (RNAi) involves sequence-specific downregulation of target genes, leading to gene silencing in vitro and in vivo. Synthetic small interfering RNAs (siRNAs), formulated with appropriate delivery agents, can serve as effective tools fo
Publikováno v:
RNA Interference ISBN: 9781607615873
RNA interference (RNAi) involves sequence-specific downregulation of target genes, leading to gene silencing in vitro and in vivo. Synthetic small interfering RNAs (siRNAs), formulated with appropriate delivery agents, can serve as effective tools fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba8910eac42473d50bb87f9e4c1cff1f
https://doi.org/10.1007/978-1-60761-588-0_26
https://doi.org/10.1007/978-1-60761-588-0_26
Autor:
Alan So, Yan Liu, Shaguna Seth, Kathy Fosnaugh, Roger C. Adami, Yoshiyuki Matsui, Rachel E. Johns, Tianying Zhu, Narendra K. Vaish, Gregory Severson, Barry Polisky, Pierrot Harvie, Yan Chen, Michael V. Templin, Pat Charmley, Susan Bell, Brian R. Granger
Publikováno v:
Cancer Research. 70:581-581
Bladder cancer and hepatocellular carcinoma are two of many cancers refractory to current treatments. Small interfering RNAs (siRNAs) are a new therapeutic modality able to specifically silence expression of targets not accessible via current small m