Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gregory Sempowski"'
Autor:
David R. Martinez, Alexandra Schäfer, Sophie Gobeil, Dapeng Li, Gabriela De la Cruz, Robert Parks, Xiaozhi Lu, Maggie Barr, Victoria Stalls, Katarzyna Janowska, Esther Beaudoin, Kartik Manne, Katayoun Mansouri, Robert J. Edwards, Kenneth Cronin, Boyd Yount, Kara Anasti, Stephanie A. Montgomery, Juanjie Tang, Hana Golding, Shaunna Shen, Tongqing Zhou, Peter D. Kwong, Barney S. Graham, John R. Mascola, David C. Montefiori, S. Munir Alam, Gregory Sempowski, Gregory D. Sempowski, Surender Khurana, Kevin Wiehe, Kevin O. Saunders, Priyamvada Acharya, Barton F. Haynes, Ralph S. Baric
Publikováno v:
Sci Transl Med
Severe acute respiratory syndrome coronaviruses 1 (SARS-CoV) and 2 (SARS-CoV-2), including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality associated with sarbecovirus infection underscores the importance of developing broa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934431ced7671dc0f6c6b4100aca29a7
https://doi.org/10.1126/scitranslmed.abj7125
https://doi.org/10.1126/scitranslmed.abj7125
Autor:
Joseph Thome, Melissa Ventevogel, Yoshiaki Ohmura, Tomoaki Kato, Gregory Sempowski, Donna Farber
Publikováno v:
The Journal of Immunology. 192:193.12-193.12
The extent to which thymopoieis is diminished over the human lifespan and how this affects the naïve T cell repertoire in peripheral tissue sites is not well characterized. In collaboration with the New York Organ Donor Network, we have attained nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f763bc50761c79dfc8e2f4bf5894ed94
https://doi.org/10.4049/jimmunol.192.supp.193.12
https://doi.org/10.4049/jimmunol.192.supp.193.12
Autor:
Lydia Barrigan, Shraddha Tuladhar, Jason Brunton, Matthew Woolard, Ching-ju Chen, Divey Saini, Richard Frothingham, Gregory Sempowski, Thomas Kawula, Jeffrey Frelinger
Publikováno v:
The Journal of Immunology. 190:186.10-186.10
Bacterial infections typically initiate both innate and adaptive immune responses. Bacterial attenuation is thought of as altered bacterial growth in the presence of constant immune pressure. In vivo screens have identified F. tularensis genes necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff24ae5618986ade5ffa4fc7a4e5c316
https://doi.org/10.4049/jimmunol.190.supp.186.10
https://doi.org/10.4049/jimmunol.190.supp.186.10
Publikováno v:
The Journal of Immunology. 186:106.3-106.3
Hematopoietic stem cells originate in the bone marrow and give rise to immune cells. Zoledronic acid (ZA) is a bisphosphonate shown to modulate skeletal and immune systems. Hip fracture patients treated with ZA had a significant increase in bone dens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a450d589555e692ae0b119438d514c
https://doi.org/10.4049/jimmunol.186.supp.106.3
https://doi.org/10.4049/jimmunol.186.supp.106.3
Publikováno v:
The Journal of Immunology. 186:52.4-52.4
Adjuvants are crucial vaccine components for enhancing immune response to immunogens. Many potential adjuvant materials have been studied for their ability to augment the response to antigens while maintaining low toxicity. A US FDA approved adjuvant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b1d5c99bd3e31a53381a487463c2462
https://doi.org/10.4049/jimmunol.186.supp.52.4
https://doi.org/10.4049/jimmunol.186.supp.52.4
Autor:
Zana Këpuska, Gregory Sempowski
Publikováno v:
The Journal of Immunology. 186:104.21-104.21
Proper thymic function is important for maintaining lifelong peripheral homeostasis of naïve and memory T cells. Age-induced thymic involution is chronic and does not recover. Acute thymus involution in settings of stress can spontaneously recover.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7422cc0c3ec05b47c75a38e00255164a
https://doi.org/10.4049/jimmunol.186.supp.104.21
https://doi.org/10.4049/jimmunol.186.supp.104.21
Publikováno v:
The Journal of Immunology. 186:113.25-113.25
Productive thymopoiesis is essential for a robust and healthy immune system. Thymus unfortunately is acutely sensitive to stress resulting in involution and decreased T cell production. Thymic involution is a complication of many clinical settings, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255b967f295eab3190e023b19e6db8ee
https://doi.org/10.4049/jimmunol.186.supp.113.25
https://doi.org/10.4049/jimmunol.186.supp.113.25
Autor:
Cong Jin, Christopher Shelburne, Guojie Li, Erin Potts, Kristina Riebe, Gregory Sempowski, Michael Foster, Soman Abraham
Publikováno v:
The Journal of Immunology. 184:141.19-141.19
Numerous epidemiological studies have related the exacerbation of allergic asthma with exposure to increased ambient particles from air pollutants. However, the mechanism by which particulate allergens (pAg) exacerbate allergic asthma remains undefin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4a7cef369259cc723049e95c048246e
https://doi.org/10.4049/jimmunol.184.supp.141.19
https://doi.org/10.4049/jimmunol.184.supp.141.19
Publikováno v:
The Journal of Immunology. 184:36.21-36.21
Normally, neutrophil pools are maintained by “steady-state” granulopoiesis. Inflammation, however, is thought to elicit growth factors that accelerate neutrophil production through a distinct developmental program known as “emergency” granulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e6f1f5e1ab42d53b3f9ac0a94380afb
https://doi.org/10.4049/jimmunol.184.supp.36.21
https://doi.org/10.4049/jimmunol.184.supp.36.21