Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gregory Raymond Savage"'
Publikováno v:
The Journal of Physiology. 592:2679-2694
Key points When a blindfolded subject holds his or her arm at a particular angle, its reported position shifts over time; this is known as proprioceptive drift. Here, we show that in relation to position sense at the elbow, the direction of perceived
Publikováno v:
Chemosensory Perception. 3:118-128
Olfactory decline represents one of the earliest signs of Alzheimer’s disease (AD), and deficits in olfactory identification have now been identified in persons with amnestic mild cognitive impairment (aMCI). Whether the olfactory identification de
Autor:
Christopher C. Rowe, Pradeep J. Nathan, Kathryn A. Ellis, J. G. Chan, Julia R. Ellis, J Bradley, Henri Tochon-Danguy, Graeme O'Keefe, Rachel S. Mulligan, Victor L. Villemagne, Gregory Raymond Savage
Publikováno v:
Synapse. 63:752-763
Extensive experimental and neuropathological evidence supports the general hypothesis that decline in the basal forebrain cholinergic system contributes significantly to age-related cognitive impairment. Postmortem studies suggest reductions in neuro
Publikováno v:
Neuropsychology. 22:718-728
Mild cognitive impairment (MCI) is associated with increased risk of developing Alzheimer's disease (AD), but up to 40% of cases do not develop AD. Examining a case's specific memory profile may help distinguish which MCI cases will progress to AD: A
Autor:
Gregory Raymond Savage, Kerryn E. Pike
Publikováno v:
Journal of Neuropsychology. 2:361-372
Mild cognitive impairment (MCI) is considered a transitional stage between normal ageing and Alzheimer's disease (AD), but not all MCI cases progress to AD and there has been limited focus on how to identify who will progress. Given claims for a char
Autor:
Linda Gonzalez, Edmond Chiu, David Ames, Michael M. Saling, Gregory Raymond Savage, Georgina Johanna Lowndes
Publikováno v:
Aging, Neuropsychology, and Cognition. 15:506-522
Associate-recognition has received little attention as a potential clinical tool for detecting early Alzheimer's disease (AD). As an important preliminary stage to investigating the paradigm's diagnostic utility, we designed and administered a verbal
Autor:
Gregory Raymond Savage, Georgina Johanna Lowndes, Michael M. Saling, Linda Gonzalez, Edmond Chiu, David Ames
Publikováno v:
Journal of the International Neuropsychological Society. 14:591-600
The primary impairment in early Alzheimer's disease (AD) is encoding/consolidation, resulting from medial temporal lobe (MTL) pathology. AD patients perform poorly on cued-recall paired associate learning (PAL) tasks, which assess the ability of the
Autor:
Clare Smith, Gregory Raymond Savage, David Darby, Kerryn E. Pike, Victor L. Villemagne, Michael Woodward, Henri Tochon-Danguy, Chett A Mathis, Paul Maruff, Uwe Ackermann, John Merory, Christopher C. Rowe, Colin L. Masters, Graeme O'Keefe, Sylvia J. Gong, William E. Klunk, Steven Ng, Tiffany F. Cowie, Julie C. Price, Kerryn L Dickinson
Publikováno v:
Neurology. 68:1718-1725
I read the article by Rowe et al.1 with interest. Diagnosing Alzheimer disease (AD) in a preclinical phase would enable early implementation of therapeutic interventions which might have long-term benefits. PET technology by using the Pittsburgh comp
amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease
Autor:
William E. Klunk, Colin L. Masters, Simon Moss, Victor L. Villemagne, Chester A. Mathis, Christopher C Rowe, Kerryn E. Pike, Gregory Raymond Savage, Paul Maruff, Steven Ng
Publikováno v:
Brain. 130:2837-2844
Beta-amyloid (Abeta) deposition is pathognomic for Alzheimer's disease (AD), but may occur in normal elderly people without apparent cognitive effect. Episodic memory impairment is an early and prominent sign of AD, but its relationship with Abeta bu
Publikováno v:
Cognitive Neuropsychology. 24:162-186
The role of semantics in reading aloud remains controversial. To explore this issue, the current study examined the impact of semantic loss on reading-aloud performance in 7 patients with semantic dementia. The results revealed a heterogenous pattern