Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Gregory Raczniak"'
1
A Single Amidotransferase Forms Asparaginyl-tRNA and Glutaminyl-tRNA in Chlamydia trachomatis
Autor: Bokkee Min, Dieter Söll, Gregory Raczniak, Hubert Dominique Becker
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276 (49), pp.45862-45867. ⟨10.1074/jbc.M109494200⟩
Aminoacyl-tRNA is generally formed by aminoacyl-tRNA synthetases, a family of 20 enzymes essential for accurate protein synthesis. However, most bacteria generate one of the two amide aminoacyl-tRNAs, Asn-tRNA or Gln-tRNA, by transamidation of mischa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479829c469acba17502a12cc1d4de167
https://doi.org/10.1074/jbc.m109494200
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2
Genomics-based identification of targets in pathogenic bacteria for potential therapeutic and diagnostic use
Autor: Dieter Söll, Gregory Raczniak, Michael Ibba
Publikováno v: Toxicology. 160:181-189
The availability of numerous complete microbial genome sequences has profoundly altered our understanding of a number of fundamental biological processes. For example the enzymes involved in aminoacyl-tRNA (AA-tRNA) synthesis, the key process respons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d4aa850fc6100cb198f41ef6d18f16
https://doi.org/10.1016/s0300-483x(00)00454-6
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3
ITS-1 DNA SEQUENCE CONFIRMATION OF LEISHMANIA MAJOR AS A CAUSE OF CUTANEOUS LEISHMANIASIS FROM AN OUTBREAK FOCUS IN THE HO DISTRICT, SOUTHEASTERN GHANA
Autor: David J. Fryauff, John D. Klena, Michael D. Wilson, Margaret Kweku, Gregory Raczniak, Daniel A. Boakye, William O. Rogers, Maxwell A. Appawu, Hanafi A. Hanafi, David F. Hoel, Naiki Puplampu, Shirley Odoom, Kwadwo A. Koram
Publikováno v: The American Journal of Tropical Medicine and Hygiene. 75:502-504
We report first-time definitive evidence of human cutaneous leishmaniasis (CL) resulting from L. major infections in Ghana. The evidence is in the form of PCR testing and DNA sequence analysis of skin sample biopsies from residents of the Ho District
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38b986a20f44bafa23db462ea58ee7a3
https://doi.org/10.4269/ajtmh.2006.75.502
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4
Co-Infection of Rickettsia rickettsii and Streptococcus pyogenes: Is Fatal Rocky Mountain Spotted Fever Underdiagnosed?
Autor: Jennifer H. McQuiston, Cecilia Kato, Audrey Mitchell, Ida H. Chung, Craig Levy, Adam Bjork, Erica Weis, Maria da Gloria Carvalho, Gregory Raczniak, Amy Austin, Joanna J. Regan
Publikováno v: The American Journal of Tropical Medicine and Hygiene. 91:1154-1155
Rocky Mountain spotted fever, a tick-borne disease caused by Rickettsia rickettsii, is challenging to diagnose and rapidly fatal if not treated. We describe a decedent who was co-infected with group A β-hemolytic streptococcus and R. rickettsii. Fat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d087c7b89a6f67798ea64ac7efd98a89
https://doi.org/10.4269/ajtmh.14-0437
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5
Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades
Autor: Henry Niman, Mona Aly, Abdel-Satar Arafa, Nasr El-Sayed, Ahmed Nayel, Ahmed Abdelghani, Hala Esmat, Gregory Raczniak, Mensah Agyen-Frempong, William Ampofo, Bruce Boynton
Publikováno v: Nature Precedings.
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1,2. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 3. The gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ac3216960246a3d3da91409018eb4c3
https://doi.org/10.1038/npre.2008.459.4
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6
Aggregation of Single Nucleotide Polymorphisms in a Human H5N1 Clade 2.2 Hemagglutinin
Autor: Kenneth C. Earhart, Abdelattar Arafa, Ehab Ayoub, Ahmed S. Abdelghani, Magdi D. Saad, Marshall R. Monteville, Moustafa M. Mansour, Bruce Boynton, William Ampofo, Henry Niman, Gregory Raczniak, Ahmed Nayel, Jeffery Tjaden, Nasr El-Sayed, Mensah Agyen-Frempong, Hala Esmat, Emad Labib, Mona M. Aly
Publikováno v: Nature Precedings
The evolution of H5N1 has attracted significant interest 1-4 due to linkages with avian 5,6 and human infections 7,8. The basic tenets of influenza genetics 9 attribute genetic drift to replication errors caused by a polymerase complex that lacks a p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05476e29c4cbdc78f281bea51d1ffcec
https://doi.org/10.1038/npre.2007.743.2
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7
Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades
Autor: Henry Niman, Magdi Saad, Mona Aly, Jeffery Tjaden, Kenneth Earhart, Marshall Monteville, Moustafa Mansour, Nasr El-Sayed, Ahmed Nayel, Ahmed Abdelghani, Hala Esmat, Emad Labib, Ehab Ayoub, Abdelattar Arafa, Gregory Raczniak, Mensah Agyen-Frempong, William Ampofo, Bruce Boynton
Publikováno v: Nature Precedings.
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997. The number of confirmed human cases now exceeds 300, and the associated Case Fatality Rate exceeds 60%. The genetic d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b51d22d526a33266641f2d11c3205ab6
https://doi.org/10.1038/npre.2007.459.3
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8
Evidence for a new species of Leishmania associated with a focal disease outbreak in Ghana
Autor: Sarah Mechta, Naiki Puplampu, Magda Abbassy, David F. Hoel, Jeffrey T. Villinski, Gregory Raczniak, John D. Klena, Daniel A. Boakye
Publikováno v: Diagnostic microbiology and infectious disease. 60(3)
A previously unknown Leishmania spp., inferred by DNA sequence analysis of the small subunit ribosomal RNA gene and the internal transcribed spacer region (ITS1), was detected in tissue biopsies from patients living in the Eastern Ghanaian community
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5430d9b975e054ab3886cba51f0a9eec
https://pubmed.ncbi.nlm.nih.gov/18031968
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10
Protein synthesis in Escherichia coli with mischarged tRNA
Autor: Gregory Raczniak, Bokkee Min, Dieter Söll, Carla Polycarpo, Suk Namgoong, Hiroyuki Kobayashi, Makoto Kitabatake, Joanne Pelaschier, Benfang Ruan
Publikováno v: Journal of bacteriology. 185(12)
Two types of aspartyl-tRNA synthetase exist: the discriminating enzyme (D-AspRS) forms only Asp-tRNA Asp , while the nondiscriminating one (ND-AspRS) also synthesizes Asp-tRNA Asn , a required intermediate in protein synthesis in many organisms (but
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2200d493cc472dbfd4e1e470482e1a65
https://pubmed.ncbi.nlm.nih.gov/12775689
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