Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gregory R. Yantz"'
Autor:
Kimberly A. Gillis, Michael Gallo, Gregory R. Yantz, Steven R. Gullans, Nuno Goncalves, Christina M. D’Antoni, Rudolf Gilmanshin, Kevin M. Phillips, Lori Anne Neely, Jonathan W. Larson
Publikováno v:
Nucleic Acids Research
Herein we describe the first application of direct linear analysis (DLA) to the mapping of a bacterial artificial chromosome (BAC), specifically the 185.1 kb-long BAC 12M9. DLA is a single molecule mapping technology, based on microfluidic elongation
Autor:
Nuno Goncalves, Eugene Y. Chan, Amie Jo Hatch, Steven R. Gullans, Eugene D. Carstea, Gordon G. Wong, Rudolf Gilmanshin, Jonathan W. Larson, Anthony M. Maletta, Rebecca A. Haeusler, Gregory R. Yantz, Martin Fuchs
Publikováno v:
Genome Research. 14:1137-1146
We have developed a rapid molecular mapping technology—Direct Linear Analysis (DLA)—on the basis of the analysis of individual DNA molecules bound with sequence-specific fluorescent tags. The apparatus includes a microfluidic device for stretchin
Publikováno v:
Lab on a chip. 7(12)
A fluorescence-based integrated optics microfluidic device is presented, capable of detecting single DNA molecules in a high throughput and reproducible manner. The device integrates microfluidics for DNA stretching with two optical elements for sing
Autor:
Rebecca Charnas, Steven R. Gullans, Gregory R. Yantz, Kimberly A. Gillis, Gordon G. Wong, Rudolf Gilmanshin, Lori Anne Neely, Michael Gallo, Qun Zhong, Jonathan W. Larson, Christina M. D’Antoni, Kevin M. Phillips
Publikováno v:
Lab on a chip. 6(9)
High-throughput stretching and monitoring of single DNA molecules in continuous elongational flow offers compelling advantages for biotechnology applications such as DNA mapping. However, the polymer dynamics in common microfluidic implementations ar
Publikováno v:
Lab on a Chip; Nov2007, Vol. 7 Issue 12, p1767-1774, 8p