Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gregory R. Robbins"'
Autor:
Hee Jeung Oh, Mariam S. Aboian, Michael Y. J. Yi, Jacqueline A. Maslyn, Whitney S. Loo, Xi Jiang, Dilworth Y. Parkinson, Mark W. Wilson, Terilyn Moore, Colin R. Yee, Gregory R. Robbins, Florian M. Barth, Joseph M. DeSimone, Steven W. Hetts, Nitash P. Balsara
Publikováno v:
ACS Central Science, Vol 5, Iss 3, Pp 419-427 (2019)
Externí odkaz:
https://doaj.org/article/3515ce85610e4057823d1a4cd31dd093
Autor:
Nitash P. Balsara, Steven W. Hetts, Jacqueline A. Maslyn, Gregory R. Robbins, Mariam Aboian, Hee Jeung Oh, Michael Y. J. Yi, Florian M. Barth, T Moore, Dilworth Y. Parkinson, Joseph M. DeSimone, Colin Yee, Whitney S. Loo, Xi Jiang, Mark W. Wilson
Publikováno v:
ACS Central Science, Vol 5, Iss 3, Pp 419-427 (2019)
ACS central science, vol 5, iss 3
ACS central science, vol 5, iss 3
Despite efforts to develop increasingly targeted and personalized cancer therapeutics, dosing of drugs in cancer chemotherapy is limited by systemic toxic side effects. We have designed, built, and deployed porous absorbers for capturing chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bbfb188e8b4527d74fc4c39108eef1
https://doaj.org/article/3515ce85610e4057823d1a4cd31dd093
https://doaj.org/article/3515ce85610e4057823d1a4cd31dd093
Autor:
Tojan B. Rahhal, Marc P. Kai, J. Christopher Luft, Joseph M. DeSimone, Gregory R. Robbins, Tammy W. Shen, Catherine A. Fromen
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 12:677-687
Engineered nanoparticles have the potential to expand the breadth of pulmonary therapeutics, especially as respiratory vaccines. Notably, cationic nanoparticles have been demonstrated to produce superior local immune responses following pulmonary del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e866fdae6002ae18aeb520e5952daa0
https://doi.org/10.1016/j.nano.2015.11.002
https://doi.org/10.1016/j.nano.2015.11.002
Autor:
Agnieszka D. Truax, Beckley K. Davis, Jenny P.-Y. Ting, W. June Brickey, Gregory R. Robbins, Lu Zhang
Publikováno v:
Journal of Biological Chemistry. 287:24294-24303
Most of the nucleotide-binding domain, leucine-rich repeat (NLR) proteins regulate responses to microbial and damage-associated products. Class II transactivator (CIITA) has a distinct function as the master regulator of class II major histocompatibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74887c7061b9c92759322dfb7bf8786
https://doi.org/10.1074/jbc.m112.364604
https://doi.org/10.1074/jbc.m112.364604
Autor:
William C. Zamboni, J. Christopher Luft, James E. Bear, Amanda W. Keeler, Gregory R. Robbins, Tammy W. Shen, Joseph M. DeSimone, Marc P. Kai, Jenny P.-Y. Ting, Hailey E. Brighton, Yancey E. Luft, Catherine A. Fromen
Long-circulating nanoparticles are essential for increasing tumor accumulation to provide therapeutic efficacy. While it is known that tumor presence can alter the immune system, very few studies have explored this impact on nanoparticle circulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370797cda979d757d3d45a62f1ed7f9d
https://europepmc.org/articles/PMC4761267/
https://europepmc.org/articles/PMC4761267/
Autor:
Gregory R. Robbins, J. Christopher Luft, Marc P. Kai, Tojan B. Rahhal, Joseph M. DeSimone, Tammy W. Shen, Catherine A. Fromen
Publikováno v:
Pharmaceutical research. 32(10)
We evaluated the role of a poly(ethylene glycol) (PEG) surface coating to increase residence times and alter the cellular fate of nano- and microparticles delivered to the lung. Three sizes of PRINT hydrogel particles (80 × 320 nm, 1.5 and 6 μm don
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0976abe0585df5c6ffb13ad237fac2
https://pubmed.ncbi.nlm.nih.gov/26002743
https://pubmed.ncbi.nlm.nih.gov/26002743
Autor:
Jenny P.-Y. Ting, Gregory R. Robbins, Joseph M. DeSimone, Marc P. Kai, Catherine A. Fromen, Tammy W. Shen
Pulmonary immunization enhances local humoral and cell-mediated mucosal protection, which are critical for vaccination against lung-specific pathogens such as influenza or tuberculosis. A variety of nanoparticle (NP) formulations have been tested pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908d291215bae65d5fb0a48fe6494fc8
Autor:
Joseph M. DeSimone, Lishan Su, Karen P. McKinnon, Gregory D. Sempowski, Tammy W. Shen, Reid A. Roberts, Haitao Guo, Kevin G. Reuter, Gregory R. Robbins, Jenny P.-Y. Ting
Ideal nanoparticle (NP)-based drug and vaccine delivery vectors should be free of inherent cytotoxic or immunostimulatory properties. Therefore, determining baseline immune responses to nanomaterials is of utmost importance when designing human thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce65118ff458384ac692b20af051170d
Autor:
Gregory R. Robbins, Denis Gris, Yoshitaka Oyama, Timothy K. Eitas, Jenny P.-Y. Ting, June Brickey, Haitao Wen, Wei-Chun Chou
The nucleotide binding domain and leucine-rich repeat-containing (NLR) family of proteins is known to activate innate immunity, and the inflammasome-associated NLRs are prime examples. In contrast, the concept that NLRs can inhibit innate immunity is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912ae830951edfbc881c6e7bbe704944
Autor:
Kai Chen, Jenny P.-Y. Ting, Joseph M. DeSimone, Gregory R. Robbins, Tao Bo, Jillian L. Perry, Reid A. Roberts, James E. Bear, Stephen W. Jones, Marc P. Kai, Mary E. Napier
Extended circulation of nanoparticles in blood is essential for most clinical applications. Nanoparticles are rapidly cleared by cells of the mononuclear phagocyte system (MPS). Approaches such as grafting polyethylene glycol onto particles (PEGylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2565d501c770a6dabb2f76201006648
https://europepmc.org/articles/PMC3696555/
https://europepmc.org/articles/PMC3696555/