Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gregory R. Govoni"'
Autor:
Dana Gebhart, Stephen Lok, Simon Clare, Myreen Tomas, Mark Stares, Dean Scholl, Curtis J. Donskey, Trevor D. Lawley, Gregory R. Govoni
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Clostridium difficile is a leading cause of nosocomial infections worldwide and has become an urgent public health threat requiring immediate attention. Epidemic lineages of the BI/NAP1/027 strain type have emerged and spread through health
Externí odkaz:
https://doaj.org/article/56d6053b8e4743aea292009135fb17f2
Autor:
Iris Casuga, Frances Chan, Milton Huynh, Gregory R. Govoni, Kayla Zochowski, Thilanka Jayaweera, Janice Au-Young
Publikováno v:
Cancer Research. 82:2944-2944
Next-Generation Sequencing technology has enhanced oncology research by enabling the detection of all cancer related variants into one assay for research and drug discovery programs. The Oncomine࣪ Comprehensive Assay v3, a pan-cancer panel, used wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf534004b24baa9493b72733b42f25c
https://doi.org/10.1158/1538-7445.am2022-2944
https://doi.org/10.1158/1538-7445.am2022-2944
Autor:
Laura M McLaughlin, Gregory R Govoni, Christiane Gerke, Smita Gopinath, Kaitian Peng, Grace Laidlaw, Yueh-Hsiu Chien, Ha-Won Jeong, Zhigang Li, Matthew D Brown, David B Sacks, Denise Monack
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000671 (2009)
Host-adapted strains of Salmonella enterica cause systemic infections and have the ability to persist systemically for long periods of time despite the presence of a robust immune response. Chronically infected hosts are asymptomatic and transmit dis
Externí odkaz:
https://doaj.org/article/367bb03163aa44459e43c6b2c8cd1f6a
Autor:
Dean Scholl, Anthony M. Buckley, Dana Gebhart, Gregory R. Govoni, Gillian Douce, Stephen Lok, Joseph A. Kirk, Robert P. Fagan
Publikováno v:
Science Translational Medicine. 9
There is a medical need for antibacterial agents that do not damage the resident gut microbiota or promote the spread of antibiotic resistance. We recently described a prototypic precision bactericidal agent, Av-CD291.2, which selectively kills speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::376a43de94f787f896ba3c1789fccea3
https://doi.org/10.1126/scitranslmed.aah6813
https://doi.org/10.1126/scitranslmed.aah6813
Publikováno v:
Journal of bacteriology, vol 198, iss 20
Listeria monocytogenes is a significant foodborne human pathogen that can cause severe disease in certain high-risk individuals. L. monocytogenes is known to produce high-molecular-weight, phage tail-like bacteriocins, or “monocins,” upon inducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7646f77017a86ef6d17d914c029f4890
https://escholarship.org/uc/item/6372q45q
https://escholarship.org/uc/item/6372q45q
Autor:
Joseph A, Kirk, Dana, Gebhart, Anthony M, Buckley, Stephen, Lok, Dean, Scholl, Gillian R, Douce, Gregory R, Govoni, Robert P, Fagan
Publikováno v:
Science translational medicine. 9(406)
Avidocin-CDs are a new class of precision bactericidal agents that do not damage resident gut microbiota and are unlikely to promote the spread of antibiotic resistance. The precision killing properties result from the fusion of bacteriophage recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::904f51b8ee0854eb5b666d943119f492
https://pubmed.ncbi.nlm.nih.gov/28878013
https://pubmed.ncbi.nlm.nih.gov/28878013
Autor:
Kristin M Willner, Amy Butani, Shanmuga Sozhamannan, Steven R. Williams, Dana Gebhart, David W. Martin, Dean Scholl, Kimberly A. Bishop-Lilly, Louis-Charles Fortier, Gregory R. Govoni
Publikováno v:
Journal of Bacteriology. 194:6240-6247
Clostridium difficile causes one of the leading nosocomial infections in developed countries, and therapeutic choices are limited. Some strains of C. difficile produce phage tail-like particles upon induction of the SOS response. These particles have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faeb9c184612d7580aba4c35ddea131e
https://doi.org/10.1128/jb.01272-12
https://doi.org/10.1128/jb.01272-12
Autor:
Trevor D. Lawley, Simon Clare, Gregory R. Govoni, Dean Scholl, Stephen Lok, Myreen Tomas, Curtis J. Donskey, Dana Gebhart, Mark D. Stares
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
Clostridium difficile is a leading cause of nosocomial infections worldwide and has become an urgent public health threat requiring immediate attention. Epidemic lineages of the BI/NAP1/027 strain type have emerged and spread through health care syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f7e437972d81a8c2205cebfcba83a1
https://pubmed.ncbi.nlm.nih.gov/25895936
https://pubmed.ncbi.nlm.nih.gov/25895936
Publikováno v:
Blood. 101:3699-3707
Mutations at natural resistance-associated macrophage protein 1(Nramp1) impair phagocyte function and cause susceptibility to infections while mutations at Nramp2 (divalent metal transporter 1 [DMT1]) affect iron homeostasis and cause severe microcyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f08b07afe6678a176fd610c57d9977
https://doi.org/10.1182/blood-2002-07-2108
https://doi.org/10.1182/blood-2002-07-2108
Publikováno v:
Journal of Biological Chemistry. 275:35738-35745
Nramp2, also known as DMT1 and DCT1, is a 12-transmembrane (TM) domain protein responsible for dietary iron uptake in the duodenum and iron acquisition from transferrin in peripheral tissues. Nramp2/DMT1 produces by alternative splicing two isoforms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0598a9c586a46b5e11b02b170e52634
https://doi.org/10.1074/jbc.m005387200
https://doi.org/10.1074/jbc.m005387200