Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Gregory P. Pogue"'
Autor:
Kelsi Swope, Josh Morton, Gregory P. Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A. Simpson, Miles B. Brennan, Thomas C. Furman, Sheila Kingrey-Gebe, Theresa Martinez, Jim McDonough, Michael H. Pauly, Kevin J. Whaley, Larry Zeitlin, Barry Bratcher, Hugh Haydon
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The ongoing SARS-CoV-2 coronavirus pandemic of 2020–2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on Nicotiana benthamiana produced mAb therape
Externí odkaz:
https://doaj.org/article/0444f122130744d095e196c092b78bd8
Autor:
Jennifer K. DeMarco, Joshua M. Royal, William E. Severson, Jon D. Gabbard, Steve Hume, Josh Morton, Kelsi Swope, Carrie A. Simpson, John W. Shepherd, Barry Bratcher, Kenneth E. Palmer, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1346 (2021)
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://doaj.org/article/d948abd924354895b2c5b1c46d082bd9
Autor:
Joshua M. Royal, Carrie A. Simpson, Alison A. McCormick, Amanda Phillips, Steve Hume, Josh Morton, John Shepherd, Youngjun Oh, Kelsi Swope, Jennifer L. DeBeauchamp, Richard J. Webby, Robert W. Cross, Viktoriya Borisevich, Thomas W. Geisbert, Jennifer K. Demarco, Barry Bratcher, Hugh Haydon, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1347 (2021)
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://doaj.org/article/43b61c27594a4cee8b9a7611a625c5e8
Autor:
Hong Du, Terri L. Cameron, Stephen J. Garger, Gregory P. Pogue, Lee A. Hamm, Earl White, Kathleen M. Hanley, Gregory A. Grabowski
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 8, Pp 1646-1657 (2008)
Lysosomal acid lipase (LAL) is an essential enzyme that hydrolyzes triglycerides (TGs) and cholesteryl esters (CEs) in lysosomes. Genetic LAL mutations lead to Wolman disease (WD) and cholesteryl ester storage disease (CESD). An LAL-null (lal−/−)
Externí odkaz:
https://doaj.org/article/b29ac79e31b941a8aab0bc10a5eb7492
Autor:
Gregory P. Pogue, Clay Spinuzzi
Publikováno v:
2022 IEEE International Professional Communication Conference (ProComm).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::180489a1fcc3619080898f7bfed7b7ed
https://doi.org/10.1109/procomm53155.2022.00080
https://doi.org/10.1109/procomm53155.2022.00080
The final published version of this article is available at https://journals.sagepub.com/doi/full/10.1177/10506519221121813
Accelerators support fledgling ventures with a set curriculum, moving them through a cycle of venture development, culmin
Accelerators support fledgling ventures with a set curriculum, moving them through a cycle of venture development, culmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d261b8fc2940a47438a525bbed133b70
Autor:
Kelsi, Swope, Josh, Morton, Gregory P, Pogue, Steve, Hume, Michael H, Pauly, John, Shepherd, Carrie A, Simpson, Barry, Bratcher, Kevin J, Whaley, Larry, Zeitlin, Keith R, Davis, Hugh, Haydon
Publikováno v:
Methods in enzymology. 660
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2dd51b13b1765289cec7315a4129cef7
https://pubmed.ncbi.nlm.nih.gov/34742392
https://pubmed.ncbi.nlm.nih.gov/34742392
Autor:
Gregory P. Pogue, Steve Hume, Jennifer K. DeMarco, Josh Morton, John W. Shepherd, Jon D. Gabbard, Joshua M. Royal, Kelsi Swope, Barry Bratcher, Kenneth E. Palmer, William Severson, Carrie A. Simpson
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b329a7578b16d5aa6c0a5474182ec467
https://pubmed.ncbi.nlm.nih.gov/34835277
https://pubmed.ncbi.nlm.nih.gov/34835277
Autor:
Jennifer K. DeMarco, William Severson, Jon D. Gabbard, Kenneth E. Palmer, Daniel R. DeMarco, Gregory P. Pogue
Since entering the world stage in December of 2019, SARS-CoV-2 has impacted every corner of the globe with over 1.48 million deaths and caused untold economic damage. Infections in humans range from asymptomatic to severe disease associated with dysr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a66616ca01673d5bf536785d62370c
https://doi.org/10.1101/2021.02.22.432407
https://doi.org/10.1101/2021.02.22.432407
Autor:
Kevin J. Whaley, Barry Bratcher, Hugh Haydon, Carrie A. Simpson, Josh Morton, Keith R. Davis, Gregory P. Pogue, Michael H. Pauly, Steve Hume, Kelsi Swope, Larry Zeitlin, John W. Shepherd
Publikováno v:
Methods in Enzymology ISBN: 9780323907378
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aecff14492cc9515dbb7d65a83a54b4
https://doi.org/10.1016/bs.mie.2021.05.011
https://doi.org/10.1016/bs.mie.2021.05.011