Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gregory P. Dubé"'
Autor:
Maria M. Rubinstein, Cheryl Goss, Scott T. Avecilla, Gregory P. Dubé, Gregory J. Riely, Jodi V. Mones
Publikováno v:
Clinical Case Reports, Vol 8, Iss 2, Pp 289-292 (2020)
Abstract Pure red cell aplasia (PRCA) is a rare paraneoplastic syndrome occasionally associated with thymomas. Here, we report on the first ever use of a bovine hemoglobin‐based oxygen carrier, HBOC‐201 (HbO2 Therapeutics LLC; Hemopure®, Waltham
Externí odkaz:
https://doaj.org/article/c3cd86fc5e4947e7bc74104957d89e2a
Autor:
Gregory J. Riely, Cheryl Goss, Scott T. Avecilla, Maria M. Rubinstein, Jodi V. Mones, Gregory P. Dubé
Publikováno v:
Clinical Case Reports
Clinical Case Reports, Vol 8, Iss 2, Pp 289-292 (2020)
Clinical Case Reports, Vol 8, Iss 2, Pp 289-292 (2020)
Pure red cell aplasia (PRCA) is a rare paraneoplastic syndrome occasionally associated with thymomas. Here, we report on the first ever use of a bovine hemoglobin‐based oxygen carrier, HBOC‐201 (HbO2 Therapeutics LLC; Hemopure®, Waltham, MA) for
Autor:
Majid Rezaei, Bahar Bassiri Gharb, Brian A Figueroa, Francis Papay, Carlos Ordenana, Antonio Rampazzo, Sayf A Said, Gregory P Dubé, Lynn M. Orfahli, Srinivasan Dasarathy, Henri Brunengraber
Publikováno v:
The journal of trauma and acute care surgery. 92(2)
Ex vivo normothermic limb perfusion (EVNLP) preserves amputated limbs under near-physiologic conditions. Perfusates containing red blood cells (RBCs) have shown to improve outcomes during ex vivo normothermic organ perfusion, when compared with acell
Publikováno v:
Shock (Augusta, Ga.). 52(1S Suppl 1)
Background Because total hemoglobin in circulation ([THb]) is an established predictor of clinical outcomes in anemic individuals, the relative efficacies of resuscitation fluids to increase [THb] can be used to design better hemoglobin-based oxygen
Publikováno v:
Shock (Augusta, Ga.). 52(1S Suppl 1)
Lessons learned during 1,701 clinical uses of HBOC-201, a polymerized bovine hemoglobin-based oxygen carrier (HBOC), were identified to provide management lessons and training material for future clinical trials and use. HBOC-201 contains 13 g/dL hem
Autor:
Mario Nuño-Ayala, Rodrigo Fernández-Jiménez, Javier Sánchez-González, Ana García-Álvarez, Zafiris Zafirelis, Borja Ibanez, Jaume Aguero, Gonzalo J. López-Martín, Valentin Fuster, Juan A. Bernal, José Manuel García-Ruiz, Enrique Lara-Pezzi, Gregory P Dubé, Carlos Galán-Arriola
Publikováno v:
Basic research in cardiology. 112(2)
Reperfusion, despite being required for myocardial salvage, is associated with additional injury. We hypothesize that infarct size (IS) will be reduced by a period of bloodless reperfusion with hemoglobin-based oxygen carriers (HBOC) before blood-flo
Autor:
Bruce M. McManus, Nancy Dos Santos, Cornelis van Breemen, Warda Toma, Roshanak Rahimian, Gregory P. Dubé
Publikováno v:
European Journal of Pharmacology. 434:141-149
We report the modulatory effects of chronic oral LY139481 (raloxifene) on basal release of nitric oxide (NO) and mRNA levels of endothelial NO synthase (eNOS) in rat thoracic aorta. Constrictor dose-response curves to phenylephrine were generated bef
Autor:
James C. Russell, Gregory P Dubé, Joyce D McKendrick, Marek W. Radomski, Eduardo Salas, Jesus Murat
Publikováno v:
British Journal of Pharmacology. 124:361-369
The effects of nitric oxide (NO) on vascular reactivity and platelet function in the obese (cp/cp) and lean (+/?) JCR:LA-cp rats were investigated. Phenylephrine (PE; 0.1 nM–10 μM) induced contraction of isolated aortic rings in both genotypes (cp
Autor:
Daniel J. Haddad, Aaron K. Patton, Joan P. Blonder, Qiumei Chen, Richard E. Sievers, Gregory P. Dubé, Sarah C. Mutka, Matthew L. Springer, Gary J. Rosenthal, Sourabh Kharait, Monika Varga, Christopher S. Delany
Publikováno v:
Chen, Qiumei; Sievers, Richard E; Varga, Monika; Kharait, Sourabh; Haddad, Daniel J; Patton, Aaron K; et al.(2013). Pharmacological inhibition of S-nitrosoglutathione reductase improves endothelial vasodilatory function in rats in vivo. J. Appl. Physiol., 114(6), 752-760. doi: 10.1152/japplphysiol.01302.2012. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6nz9z6fr
Chen, Q; Sievers, RE; Varga, M; Kharait, S; Haddad, DJ; Patton, AK; et al.(2013). Pharmacological inhibition of S-nitrosoglutathione reductase improves endothelial vasodilatory function in rats in vivo. Journal of Applied Physiology, 114(6), 752-760. doi: 10.1152/japplphysiol.01302.2012. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5z3316dx
Journal of applied physiology (Bethesda, Md. : 1985), vol 114, iss 6
Chen, Q; Sievers, RE; Varga, M; Kharait, S; Haddad, DJ; Patton, AK; et al.(2013). Pharmacological inhibition of S-nitrosoglutathione reductase improves endothelial vasodilatory function in rats in vivo. Journal of Applied Physiology, 114(6), 752-760. doi: 10.1152/japplphysiol.01302.2012. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5z3316dx
Journal of applied physiology (Bethesda, Md. : 1985), vol 114, iss 6
Nitric oxide (NO) exerts a wide range of cellular effects in the cardiovascular system. NO is short lived, but S-nitrosoglutathione (GSNO) functions as a stable intracellular bioavailable NO pool. Accordingly, increased levels can facilitate NO-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db4d95f00c3ac5ad7bfea451a9d251a
http://www.escholarship.org/uc/item/6nz9z6fr
http://www.escholarship.org/uc/item/6nz9z6fr