Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Gregory P Bisson"'
Publikováno v:
Public Health in Practice, Vol 7, Iss , Pp 100483- (2024)
Objectives: In the United States, a federal emergency program has made SARS-CoV-2 self-test kits available at no cost. It is unclear how widely free tests are preferred. We conducted a survey to estimate the proportion of respondents who do not prefe
Externí odkaz:
https://doaj.org/article/8808d654ac444ff3b226412337afad4c
Autor:
Yeonsoo Baik, Pholo Maenetje, Diana Schramm, Caroline Tiemessen, Itai Ncube, Gavin Churchyard, Robert Wallis, Mboyo-di-tamba Vangu, Hardy Kornfeld, Yun Li, Sara C. Auld, Gregory P. Bisson
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Patients with tuberculosis (TB) and HIV often present with impairments in lung function and exercise capacity after treatment. We evaluated clinical and immunologic variables associated with a minimum clinically important differen
Externí odkaz:
https://doaj.org/article/19eaeaebfb4c4c90a81280d5baa856f7
Autor:
Sara C. Auld, Hardy Kornfeld, Pholo Maenetje, Mandla Mlotshwa, William Chase, Mboyo di-Tamba Vangu, Drew A. Torigian, Robert S. Wallis, Gavin Churchyard, Gregory P. Bisson
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background While tuberculosis is considered a risk factor for chronic obstructive pulmonary disease, a restrictive pattern of pulmonary impairment may actually be more common among tuberculosis survivors. We aimed to determine the nature of
Externí odkaz:
https://doaj.org/article/dc9310371e1a41d09efdd268d96a87c0
Autor:
Sonya Krishnan, Artur T. L. Queiroz, Amita Gupta, Nikhil Gupte, Gregory P. Bisson, Johnstone Kumwenda, Kogieleum Naidoo, Lerato Mohapi, Vidya Mave, Rosie Mngqibisa, Javier R. Lama, Mina C. Hosseinipour, Bruno B. Andrade, Petros C. Karakousis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tuberculosis (TB) accounts for disproportionate morbidity and mortality among persons living with HIV (PLWH). Conventional methods of TB diagnosis, including smear microscopy and Xpert MTB/RIF, have lower sensitivity in PLWH. Novel high-throughput ap
Externí odkaz:
https://doaj.org/article/589f5adbaf09447290662fd4d74b222e
Autor:
Isaac Zentner, Hyun-moon Back, Leonid Kagan, Selvakumar Subbian, Jyothi Nagajyothi, Shashikant Srivastava, Jotam Pasipanodya, Tawanda Gumbo, Gregory P. Bisson, Christopher Vinnard
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundThe potential for hepatotoxicity during isoniazid-based tuberculosis (TB) treatment presents a major challenge for TB control programs worldwide. We sought to determine whether pharmacokinetic exposures of isoniazid and its metabolites were
Externí odkaz:
https://doaj.org/article/88c5b1cb32684316808494ef3e6882d1
Autor:
Isaac Zentner, Chawangwa Modongo, Nicola M. Zetola, Jotam G. Pasipanodya, Shashikant Srivastava, Scott K. Heysell, Stellah Mpagama, Hans P. Schlect, Tawanda Gumbo, Gregory P. Bisson, Christopher Vinnard
Publikováno v:
International Journal of Infectious Diseases, Vol 68, Iss , Pp 18-23 (2018)
Objectives: Pyrazinamide is a key drug in the first-line treatment regimen for tuberculosis, with a potent sterilizing effect. Although low pyrazinamide peak serum concentrations (Cmax) are associated with poor treatment outcomes, many resource-const
Externí odkaz:
https://doaj.org/article/da7f0f48aca64586815f2625611c01a0
Autor:
Shruthi Ravimohan, Neo Tamuhla, Shiang-Ju Kung, Kebatshabile Nfanyana, Andrew P. Steenhoff, Robert Gross, Drew Weissman, Gregory P. Bisson
Publikováno v:
EBioMedicine, Vol 3, Iss C, Pp 100-107 (2016)
Background: HIV-infected patients with pulmonary TB (pTB) can have worsening of respiratory symptoms as part of TB-immune reconstitution inflammatory syndrome (TB-IRIS) following antiretroviral therapy (ART) initiation. Thus, reconstitution of immune
Externí odkaz:
https://doaj.org/article/41781b9445eb4d23862259e17b72e1dc
Publikováno v:
European Respiratory Review, Vol 27, Iss 147 (2018)
A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high prevalence and its association with reduced quality of life. Importantl
Externí odkaz:
https://doaj.org/article/4f456356f8bd416482fb7c1e1803a971
Autor:
Christopher Vinnard, Shruthi Ravimohan, Neo Tamuhla, Jotam Pasipanodya, Shashikant Srivastava, Chawangwa Modongo, Nicola M Zetola, Drew Weissman, Tawanda Gumbo, Gregory P Bisson
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187624 (2017)
Pyrazinamide is the main driver of sterilizing effect in the standard regimen in adults and older children, and this effect is concentration-dependent. Tuberculosis patients co-infected with human immunodeficiency virus (HIV) have an increased risk f
Externí odkaz:
https://doaj.org/article/f1ea380e4fbf4d8faf32e172a3a16b79
Autor:
Krina Mehta, Navaneeth Narayanan, Scott K. Heysell, Gregory P. Bisson, Selvakumar Subbian, Natalia Kurepina, Barry N. Kreiswirth, Christopher Vinnard
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 137
Our objective was to investigate the role of patient pharmacogenetic variability in determining site of action target attainment during tuberculous meningitis (TBM) treatment. Rifampin and isoniazid PBPK model that included SLCO1B1 and NAT2 effects o