Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Gregory N. Gan"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 1, Pp 108-119 (2024)
Head and neck cancer (HNC) is a challenging disease that lacks effective treatment, particularly in the cases that spread locoregionally and metastasize distantly, dramatically reducing patient survival rates. Expanding the understanding of the mecha
Externí odkaz:
https://doaj.org/article/b2a1a578067741b2bd634d2b7e4b4172
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundProton minibeam radiation therapy (pMBRT) can deliver spatially fractionated dose distributions with submillimeter resolution. These dose distributions exhibit significant heterogeneity in both depth and lateral directions. Accurate charact
Externí odkaz:
https://doaj.org/article/f9ec6afb13fc4284a95fdd5a95a900be
Publikováno v:
Cancer Reports, Vol 4, Iss 4, Pp n/a-n/a (2021)
Abstract Background Lung is the most common site of distant metastasis for patients with head and neck squamous cell carcinoma (HNSCC). However, differentiating second primary lung cancers from metastasis may be difficult for p16 negative HNSCC. Case
Externí odkaz:
https://doaj.org/article/bfcd7bab3a264aea83e241fdd01c6907
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-3 (2020)
Abstract The life expectancy of extensive-stage small cell lung (ES-SCLC) cancer patients has not improved in the last 2–3 decades until two recent trials (CASPIAN and IMpower133) showing the addition of anti-programmed death ligand (PD-L1) therapy
Externí odkaz:
https://doaj.org/article/b5fc194b7be64e59acf6022c4ba06fd3
Autor:
Ryan T. Morse, Rohit G. Ganju, Gregory N. Gan, Ying Cao, Prakash Neupane, Kiran Kakarala, Yelizaveta Shnayder, Christopher E. Lominska
Publikováno v:
Cancers, Vol 14, Iss 9, p 2094 (2022)
This study was performed to identify treatment related toxicities in older adults undergoing concurrent chemoradiotherapy for head and neck cancer and nutritional and skeletal muscle measures that might identify frailty. Imaging analysis was done wit
Externí odkaz:
https://doaj.org/article/ea917d74c12e464a9db480c2b55b08c5
Autor:
Ryan, Morse, Rohit G, Ganju, Rishi, Neeranjun, Gregory N, Gan, Ying, Cao, Prakash, Neupane, Kiran, Kakarala, Yelizaveta, Shnayder, Christopher E, Lominska
Publikováno v:
Chemotherapy. 68:35-43
Introduction: Standard of care for radiosensitization in head and neck squamous cell carcinoma (HNSCC) is concurrent chemoradiotherapy (CCRT) with high-dose cisplatin. The optimal chemoradiation regimen for patients medically unfit for cisplatin is u
Autor:
Tuleen Sawaf, Celina G. Virgen, Bryan Renslo, Nathan Farrokhian, Katherine M. Yu, Shaan N. Somani, Andrés M. Bur, Kiran Kakarala, Yelizaveta Shnayder, Gregory N. Gan, Evan M. Graboyes, Kevin J. Sykes
Publikováno v:
JAMA Otolaryngology–Head & Neck Surgery.
ImportanceTimely initiation of postoperative radiation therapy (PORT) is associated with reduced recurrence rates and improved overall survival in patients with head and neck squamous cell carcinoma (HNSCC). Measurement of the association of social-e
Autor:
Antonio Jimeno, Aik-Choon Tan, Marileila Varella-Garcia, Barbara A. Frederick, Francois Wilhelm, Dara L. Aisner, Sarah M. Takimoto, Daniel Sehrt, Brian W. Vogler, Gregory N. Gan, Justin Eagles-Soukup, Adrian Umpierrez, Phuong Le, J. Jason Morton, David P. Astling, Magdalena J. Glogowska, Daniel W. Bowles, Stephen B. Keysar, Ryan T. Anderson
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e7717de4950956e210d0d4a5249dc
https://doi.org/10.1158/1535-7163.22497478
https://doi.org/10.1158/1535-7163.22497478
Autor:
Antonio Jimeno, Aik-Choon Tan, Marileila Varella-Garcia, Barbara A. Frederick, Francois Wilhelm, Dara L. Aisner, Sarah M. Takimoto, Daniel Sehrt, Brian W. Vogler, Gregory N. Gan, Justin Eagles-Soukup, Adrian Umpierrez, Phuong Le, J. Jason Morton, David P. Astling, Magdalena J. Glogowska, Daniel W. Bowles, Stephen B. Keysar, Ryan T. Anderson
The dual pathway inhibitor rigosertib inhibits phosphoinositide 3-kinase (PI3K) pathway activation as well as polo-like kinase 1 (PLK1) activity across a broad spectrum of cancer cell lines. The importance of PIK3CA alterations in squamous cell carci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36906326f4b2438531275d5ad4819da3
https://doi.org/10.1158/1535-7163.c.6535627.v1
https://doi.org/10.1158/1535-7163.c.6535627.v1
Autor:
Antonio Jimeno, Xiao-Jing Wang, John I. Song, Andrew Thorburn, M. Scott Lucia, Fred R. Hirsch, Hilary Serracino, Justin R. Eagles-Soukup, Gregory N. Gan, Daniel B. Sehrt, Sarah M. Takimoto, Magdalena J. Glogowska, Pamela Fernandez, Jackie Thorburn, Brian W. Vogler, Jeramiah J. Paylor, Daniel W. Bowles, J. Jason Morton, Ryan T. Anderson, Phuong N. Le, Stephen B. Keysar
PDF file - 1255K, Confirmation of GLI1 modulation by EGFR activation (S1); Epithelial gene expression profile and morphology predicts erlotinib sensitivity in HNSCC cell lines (S2); Zeb1 transcription factor is key driver of EGF induced EMT (S3); EGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974366581a1d358ebdce703ca2a05791
https://doi.org/10.1158/0008-5472.22397691.v1
https://doi.org/10.1158/0008-5472.22397691.v1