Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gregory M. Orlowski"'
Publikováno v:
JAAD Case Reports, Vol 40, Iss , Pp 11-13 (2023)
Externí odkaz:
https://doaj.org/article/4eace87bf7514f92a0c6c8d6c71c8e4d
Publikováno v:
JAAD Case Reports, Vol 6, Iss 10, Pp 1075-1078 (2020)
Externí odkaz:
https://doaj.org/article/deb4671ac8744e3dab9b0ebc80de4082
Autor:
Neil B. Marya, Courtney Stead, Gregory M. Orlowski, Christina Luffman, Shahrad Hakimian, Zendee Elaba
Publikováno v:
Case Reports in Gastrointestinal Medicine, Vol 2021 (2021)
Case Reports in Gastrointestinal Medicine
Case Reports in Gastrointestinal Medicine
Sweet syndrome is a rare skin condition characterized by painful papules, nodules, or plaques with dense neutrophilic infiltrate in the upper dermis. It has been observed as idiopathic (classical), malignancy-associated, and drug-induced. The pathoge
Publikováno v:
Cutis. 103(6)
Atypical vascular lesions (AVLs) of the breast are purple papules or nodules that have been reported in breast cancer patients following radiation treatment, typically presenting with fewer than 5 lesions at diagnosis. We report a patient with 29 les
Autor:
Hiroshi Kataoka, Jeff D. Colbert, Matthew Bogyo, Gregory M. Orlowski, Shruti Sharma, Francis Ka-Ming Chan, Stephanie A. Robertson, Kenneth L. Rock
Sterile particles cause several chronic, inflammatory diseases, characterized by repeating cycles of particle phagocytosis and inflammatory cell death. Recent studies have proposed that these processes are driven by the NLRP3 inflammasome, a platform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b62101e49c6e140683f17a2bb254df
https://europepmc.org/articles/PMC6608057/
https://europepmc.org/articles/PMC6608057/
Autor:
Janet Plescia, Candace A. Gilbert, Christine M. Powers, Alonzo H. Ross, Christopher M. Raskett, Gregory M. Orlowski, Dario C. Altieri, Takehiko Dohi, Markus D. Siegelin
Publikováno v:
Journal of Clinical Investigation. 121:1349-1360
Fine tuning of the protein folding environment in subcellular organelles, such as mitochondria, is important for adaptive homeostasis and may participate in human diseases, but the regulators of this process are still largely elusive. Here, we have s
Autor:
Stephanie A. Robertson, Jeff D. Colbert, Kenneth L. Rock, Shruti Sharma, Gregory M. Orlowski, Matthew Bogyo
Sterile particles induce robust inflammatory responses that underlie the pathogenesis of diseases like silicosis, gout, and atherosclerosis. A key cytokine mediating this response is IL-1β. The generation of bioactive IL-1β by sterile particles is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff094a22c901567828e099ff9740892
https://europepmc.org/articles/PMC4530060/
https://europepmc.org/articles/PMC4530060/
Autor:
Mark J. Shlomchik, Katherine A. Fitzgerald, Jennie Chan, Ann Marshak-Rothstein, Shrutie Sharma, Leslie J. Berg, Ribhu Nayar, Allison M. Campbell, Kerstin Nündel, Annie H. Huyler, Stefan A. Schattgen, Chandra Mohan, Gregory M. Orlowski
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Cytosolic DNA-sensing pathways that signal via Stimulator of interferon genes (STING) mediate immunity to pathogens and also promote autoimmune pathology in DNaseII- and DNaseIII-deficient mice. In contrast, we report here that STING potently suppres
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 189(7)
The sterile inflammatory response to cell death and irritant crystals is medically important because it causes disease. Although these stimuli are structurally distinct, they cause inflammation through a common pathway that requires the cytokine IL-1
Autor:
Chaohong Liu, Wenxia Song, Arpita Upadhyaya, Heather Miller, Gregory M. Orlowski, Haiyin Hang
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 188(7)
B cells encounter both soluble Ag (sAg) and membrane-associated Ag (mAg) in the secondary lymphoid tissue, yet how the physical form of Ag modulates B cell activation remains unclear. This study compares actin reorganization and its role in BCR signa