Výsledky vyhledávání - "Gregory M. Mayhew"

Akademický článek

Mesenchymal gene expression subtyping analysis for early-stage human papillomavirus-negative head and neck squamous cell carcinoma reveals prognostic and predictive applications

Autor: Gregory M. Mayhew, Joshua M. Uronis, David Neil Hayes, Jose P. Zevallos

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Patients with oral cavity squamous cell carcinoma (OCSCC) are predominantly human papillomavirus (HPV)(−), and treatment typically involves surgical resection ± neck dissection, followed by radiation ± chemotherapy. We previously described four m

Externí odkaz: https://doaj.org/article/33bf6ffca9d14ee49feb01a110ac7a53

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Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL2: A Real-world Evidence Study of Patients with Advanced Renal Cancer

Autor: Joel R. Eisner, Kirk D. Beebe, Gregory M. Mayhew, Yoichiro Shibata, Yuelong Guo, Carol Farhangfar, Farhang Farhangfar, Joshua M. Uronis, Jill Mooney, Michael V. Milburn, David Foureau, Richard L. White, Asim Amin, Marcos E. Milla

Publikováno v: Cancer Research Communications. 2:894-903

Recombinant human high-dose IL2 (HD-IL2; aldesleukin) was one of the first approved immune-oncology agents based upon clinical activity in renal cell carcinoma (RCC) and metastatic melanoma but use was limited due to severe toxicity. Next-generation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3af86004040503294c91ba86fa069a5e
https://doi.org/10.1158/2767-9764.crc-21-0153

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Association of Antifolate Response Signature Status and Clinical Activity of Pemetrexed-Platinum Chemotherapy in Non-Small Cell Lung Cancer - The Piedmont Study

Autor: Joel R. Eisner, Gregory M. Mayhew, James M. Davison, Kirk D. Beebe, Yoichiro Shibata, Yuelong Guo, Carol Farhangfar, Farhang Farhangfar, Joshua M. Uronis, Jeffrey M. Conroy, Michael V. Milburn, David Neil. Hayes, Kathryn F. Mileham

Publikováno v: Clinical Cancer Research.

Purpose: The Piedmont study is a prospectively designed retrospective evaluation of a new 48-gene antifolate response signature (AF-PRS) in patients with locally advanced/metastatic NS-NSCLC treated with pemetrexed-containing platinum doublet chemoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43c4953b0bb03f5b73d0ac32e56d115c
https://doi.org/10.1158/1078-0432.ccr-22-2558

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Data from Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL2: A Real-world Evidence Study of Patients with Advanced Renal Cancer

Autor: Marcos E. Milla, Asim Amin, Richard L. White, David Foureau, Michael V. Milburn, Jill Mooney, Joshua M. Uronis, Farhang Farhangfar, Carol Farhangfar, Yuelong Guo, Yoichiro Shibata, Gregory M. Mayhew, Kirk D. Beebe, Joel R. Eisner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aee2f498634f181e0903dde0904d827
https://doi.org/10.1158/2767-9764.c.6550872.v1

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Supp Table test from Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL2: A Real-world Evidence Study of Patients with Advanced Renal Cancer

this is a test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd889514c515c62aa335b1a1f130c0
https://doi.org/10.1158/2767-9764.22545183

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Table S1 and Table S2 from Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL2: A Real-world Evidence Study of Patients with Advanced Renal Cancer

40 gene IL-2 response classifier and related immune cell types

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e912be1d5a6174fc4d7074ca2edfe78
https://doi.org/10.1158/2767-9764.22545180

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Real-world data validation of the PurIST pancreatic ductal adenocarcinoma gene expression classifier and its prognostic implications

Autor: Stephane Wenric, James M. Davison, John Guittar, Gregory M. Mayhew, Kirk D. Beebe, Yun E. Wang, Amrita A. Iyer, Hyunseok P. Kang, Michael V. Milburn, Vincent Chung, Tanios Bekaii-Saab, Charles M. Perou

BackgroundPancreatic ductal adenocarcinoma (PDAC) is amongst the deadliest cancers, with few modern tools to inform patient prognosis and help guide treatment options. Transcriptome-based molecular subtyping is one emerging technology that has been e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe5f2a6c4b61b76f6b921ebceead1bf2
https://doi.org/10.1101/2023.02.23.23286356

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Abstract A002: Purity Independent Subtyping of Tumor (PurIST): Real-world data validation of a pancreatic ductal adenocarcinoma (PDAC) gene expression classifier and its prognostic implications

Autor: Stephane Wenric, James M. Davison, Yun E. Wang, Gregory M. Mayhew, Kirk Beebe, Hyunseok P. Kang, Michael V. Milburn, Vincent Chung, Tanios Bekaii-Saab, Charles M. Perou

Publikováno v: Cancer Research. 82:A002-A002

Background: PDAC is a highly morbid disease with no validated biomarkers for first-line (1L) treatment selection. The PurIST single-sample molecular subtyping gene signature, initially described by Rashid et al. (Clin. Cancer Res., 2020), classifies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdfe738dcbb3d20b6f0b44a9fb92b791
https://doi.org/10.1158/1538-7445.panca22-a002

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Correction to: Fibroblast growth factor receptor 3 alterations and response to immune checkpoint inhibition in metastatic urothelial cancer: a real world experience

Autor: Tracy L. Rose, William H. Weir, Gregory M. Mayhew, Yoichiro Shibata, Patrick Eulitt, Joshua M. Uronis, Mi Zhou, Matthew Nielsen, Angela B. Smith, Michael Woods, Michele C. Hayward, Ashley H. Salazar, Matthew I. Milowsky, Sara E. Wobker, Katrina McGinty, Michael V. Millburn, Joel R. Eisner, William Y. Kim

Publikováno v: British Journal of Cancer. 126:1237-1237

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96a18f3be50748b01cf0b45d80ab500e
https://doi.org/10.1038/s41416-022-01781-y

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