Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gregory M. Heestand"'
Autor:
Billy T. Lau, Alison Almeda, Marie Schauer, Madeline McNamara, Xiangqi Bai, Qingxi Meng, Mira Partha, Susan M. Grimes, HoJoon Lee, Gregory M. Heestand, Hanlee P. Ji
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Epigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for detecting and characterizing diseases such as cancer. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This
Externí odkaz:
https://doaj.org/article/e323638932ce446b90aecb9fb1f4e521
Autor:
Olga Generalova, Mohana Roy, Evan Hall, Sumit A. Shah, Kristen Cunanan, Touran Fardeen, Brianna Velazquez, Gilbert Chu, Bianca Bruzzone, Anna Cabot, George A. Fisher, Sandy Srinivas, Alice C. Fan, Sigurdis Haraldsdottir, Heather A. Wakelee, Joel W. Neal, Sukhmani K. Padda, Tyler Johnson, Gregory M. Heestand, Robert W. Hsieh, Kavitha Ramchandran
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-11 (2021)
Abstract Background Patient reported outcomes (PROs) have been associated with improved symptom management and quality of life in patients with cancer. However, the implementation of PROs in an academic clinical practice has not been thoroughly descr
Externí odkaz:
https://doaj.org/article/dbafc61564464849b330b75953721f50
Autor:
Razelle Kurzrock, Gregory M. Heestand, Joel Baumgartner, Sadakatsu Ikeda, Paul T. Fanta, Paul Riviere
We aimed to assess the utility of a novel, noninvasive method of detecting genomic alterations in patients with gastrointestinal malignancies, i.e., the use of liquid biopsies to obtain blood-derived circulating tumor DNA (ctDNA) through an analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6fe63145abd9d98320d1f3abcf1c41
https://doi.org/10.1158/1535-7163.c.6537993.v1
https://doi.org/10.1158/1535-7163.c.6537993.v1
Autor:
Billy T. Lau, Alison Almeda, Marie Schauer, Madeline McNamara, Xiangqi Bai, Qingxi Meng, Mira Partha, Susan M. Grimes, HoJoon Lee, Gregory M. Heestand, Hanlee P. Ji
Epigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for characterizing diseases. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This approach generated up to hundreds of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d7dae798589701532a70675e216a0cd
https://doi.org/10.1101/2022.06.22.497080
https://doi.org/10.1101/2022.06.22.497080
Autor:
Sukhmani K. Padda, Touran Fardeen, George A. Fisher, Tyler Johnson, Gilbert Chu, Bianca Bruzzone, Brianna Velazquez, Gregory M. Heestand, Olga Generalova, Sigurdis Haraldsdottir, Sandy Srinivas, Kristen M. Cunanan, Mohana Roy, Robert W. Hsieh, Joel W. Neal, Heather A. Wakelee, Sumit A. Shah, Evan T. Hall, Anna Cabot, Kavitha Ramchandran, Alice C. Fan
Publikováno v:
Journal of Patient-Reported Outcomes
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-11 (2021)
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-11 (2021)
Background Patient reported outcomes (PROs) have been associated with improved symptom management and quality of life in patients with cancer. However, the implementation of PROs in an academic clinical practice has not been thoroughly described. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fbeeda8067be554d051f708c25d6c3
https://doi.org/10.1186/s41687-021-00358-2
https://doi.org/10.1186/s41687-021-00358-2
Publikováno v:
Gastric Cancer. 23:175-183
Gastroesophageal junction (GEJ) cancers can be treated with equipoise using neoadjuvant chemoradiation (NACRT) or chemotherapy alone (NAC), but the comparative outcomes are unclear. Patients with non-metastatic T2-4 or N1-3 GEJ adenocarcinoma who und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad50e5914bb85fe919d4a3a656e801f
https://doi.org/10.1007/s10120-019-00980-6
https://doi.org/10.1007/s10120-019-00980-6
Autor:
Alexander Kuo, Igor F. Tsigelny, Sadakatsu Ikeda, Yuko Kono, Jason K. Sicklick, Åge A. Skjevik, Scott M. Lippman, Gregory M. Heestand, Richard B. Lanman, AmirAli Talasaz, Razelle Kurzrock, Michel H. Mendler, Kimberly C. Banks
Publikováno v:
The Oncologist
This article reports unique aspects of the management of hepatocellular carcinoma. The study aimed to determine if next‐generation sequencing of blood‐derived circulating tumor DNA from patients with hepatocellular carcinoma could identify action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539d7c44de208b5a3ccbd4738852031f
https://doi.org/10.1634/theoncologist.2017-0479
https://doi.org/10.1634/theoncologist.2017-0479
Autor:
Razelle Kurzrock, Gregory M. Heestand, Paul Riviere, Joel M. Baumgartner, Paul T. Fanta, Sadakatsu Ikeda
Publikováno v:
Molecular cancer therapeutics, vol 17, iss 1
11574 Background: Liquid biopsy of circulating tumor DNA (ctDNA) is a novel method of detecting genetic alterations in cancer patients without tissue acquisition. Methods: Our analysis surveyed the genomic landscape of 213 patients with various gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bb26b0078463ce1a41611f1942eca8
https://doi.org/10.1158/1535-7163.mct-17-0360
https://doi.org/10.1158/1535-7163.mct-17-0360
Publikováno v:
European journal of cancer (Oxford, England : 1990)
Background Topoisomerase I (TOPO1) and topoisomerase IIα (TOP2A) are specific targets of multiple chemotherapy drugs. Increased expression of TOPO1 protein and amplification of the TOP2A gene have been associated with treatment response in colorecta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bededa5797b7dba718fe9bc828890136
http://europepmc.org/articles/PMC5613945
http://europepmc.org/articles/PMC5613945
Autor:
Lincoln Nadauld, Bryce Moulton, Hanlee P. Ji, Gregory M. Heestand, Derrick S. Haslem, Alison Almeda, Christina Wood-Bouwens, Hojoon Lee
Publikováno v:
J Mol Diagn
As a high-performance solution for longitudinal monitoring of patients being treated for metastatic cancer, a single-color digital PCR (dPCR) assay that detects and quantifies specific cancer mutations present in circulating tumor DNA (ctDNA) was dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f8856ea13cd7dcded3be2d680be912
https://pubmed.ncbi.nlm.nih.gov/31837432
https://pubmed.ncbi.nlm.nih.gov/31837432