Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gregory M. Adamson"'
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 153
Cyclamen aldehyde (CA; 3-(4-isopropylphenyl)-2-methylpropanal) is a widely used fragrance material. Repeated dose studies in rats revealed adverse effects on sperm maturation. Here we review all the mechanistic and in vivo evidence, to determine rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f628c9470465a088d2789d429e7463d
https://pubmed.ncbi.nlm.nih.gov/33930481
https://pubmed.ncbi.nlm.nih.gov/33930481
Autor:
Adrian Nordone, Lu Hostettler, Andreas Natsch, Remo P. Badertscher, Gregory M. Adamson, Heike Laue, Yumiko Weiner-Sekiya, Tina Haupt
Publikováno v:
Archives of toxicology. 94(12)
A number of para-substituted benzoic acids (p-BA) and chemicals metabolized to p-BA have been found to confer adverse effects in male rats on sperm viability, motility, and morphology. These effects are putatively associated with the metabolism of p-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6082b858d321802b9af99cdceb3017b4
https://pubmed.ncbi.nlm.nih.gov/33057782
https://pubmed.ncbi.nlm.nih.gov/33057782
Autor:
Gregory M. Adamson, Katherine Sarlo, J. David Innis, Victoria L. Hollis, D. Bruce Kirchner, Laura S. Babcock
Publikováno v:
Journal of Immunotoxicology. 1:71-77
Use of enzymes in cosmetic products is novel and the safety of these products is not well understood. The safety of a prototype enzyme-containing body moisturizer lotion was tested via measures of skin compatibility and potential to induce protease-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dd3e1908164b44669172bb33615c6c
https://doi.org/10.1080/15476910490496249
https://doi.org/10.1080/15476910490496249
Autor:
Gregory M. Adamson, Ruth E. Billings
Publikováno v:
Archives of Biochemistry and Biophysics. 294:223-229
Tumor necrosis factor alpha (TNF alpha) is a macrophage-derived cytokine which participates in homeostatic tissue repair. It is also a potentially useful antitumor agent. Liver toxicity, however, limits TNF alpha's clinical utility and suggests that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c13e4d66ec5da2f26fa23439e462ab4
https://doi.org/10.1016/0003-9861(92)90161-o
https://doi.org/10.1016/0003-9861(92)90161-o
Publikováno v:
Pediatric Research. 29:496-499
The hepatotoxicity of paracetamol in mice of 2, 3, 8–10, 24–26, 32–34, and 52–54 wk of age was determined by lethality data, histopathologic examination of the liver, and appearance of glutamate-pyruvate transaminase and glutamate-oxaloacetat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9ca60c7afa4dbb9d0aa46093778855
https://doi.org/10.1203/00006450-199105010-00016
https://doi.org/10.1203/00006450-199105010-00016
Autor:
Andrew W. Harman, Gregory M. Adamson
Publikováno v:
Biochemical pharmacology. 45(11)
The effect of acetaminophen (APAP) exposure on the formation of oxidized glutathione (GSSG) was investigated in cultured mouse hepatocytes to determine if oxidative damage is involved in the toxicity of this drug. Incubations of hepatocytes for 24 hr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df95f4cfc42553a37f15d7e8c134fcd6
https://pubmed.ncbi.nlm.nih.gov/8517869
https://pubmed.ncbi.nlm.nih.gov/8517869
Publikováno v:
Toxicology letters.
Paracetamol toxicity in mouse hepatocytes involved oxidative stress initiated by the formation of NAPQI. This oxidative component of paracetamol injury is associated with the latter stages of the poisoning process. Ebselen, a drug with GSH-peroxidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a3ff05ff0caec4a9543645bde1505c
https://pubmed.ncbi.nlm.nih.gov/1471211
https://pubmed.ncbi.nlm.nih.gov/1471211
Autor:
Andrew W. Harman, Gregory M. Adamson
Publikováno v:
Biochemical Pharmacology. 37:4183-4190
Age-related changes of susceptibility to hepatotoxicity induced by four hepatotoxic compounds were investigated using an isolated mouse hepatocyte model. Hepatocytes isolated from 2-week-old mice and adult mice (8–10 weeks old) were exposed to diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494c1b2d649a95619e682977f2104b3e
https://doi.org/10.1016/0006-2952(88)90114-1
https://doi.org/10.1016/0006-2952(88)90114-1