Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Gregory L. Gerdeman"'
Publikováno v:
Journal of Experimental Biology. 215:1331-1336
SUMMARY Humans report a wide range of neurobiological rewards following moderate and intense aerobic activity, popularly referred to as the ‘runner’s high’, which may function to encourage habitual aerobic exercise. Endocannabinoids (eCBs) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379d142aba4183ec049a4b1f2fb22fc5
https://doi.org/10.1242/jeb.063677
https://doi.org/10.1242/jeb.063677
Autor:
Kevin M. Middleton, Rashmi S. Wijeratne, Gregory L. Gerdeman, Theodore Garland, David A. Raichlen, Thomas H. Meek, Brooke K. Keeney
Publikováno v:
Behavioural Pharmacology. 19:812-820
Exercise is a naturally rewarding behaviour in human beings and can be associated with feelings of euphoria and analgesia. The endocannabinoid system may play a role in the perception of neurobiological rewards during and after prolonged exercise. Mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00a28188658c8cfdc280471e712a90c
https://doi.org/10.1097/fbp.0b013e32831c3b6b
https://doi.org/10.1097/fbp.0b013e32831c3b6b
Publikováno v:
Neuropsychopharmacology. 33:2747-2759
The CB(1) cannabinoid receptor is implicated in the rewarding properties of many drugs of abuse, including cocaine. While CB(1) receptor involvement in the acute rewarding properties of cocaine is controversial, CB(1) antagonists such as SR141716 (ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9387f8177430b24be66984852b7b19c5
https://doi.org/10.1038/sj.npp.1301648
https://doi.org/10.1038/sj.npp.1301648
Publikováno v:
The Journal of Neuroscience. 24:1673-1679
Activation of the CB1 cannabinoid receptor inhibits neurotransmission at numerous synapses in the brain. Indeed, CB1 is essential for certain types of both short- and long-term synaptic depression. It was demonstrated recently that CB1 is critical fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c0e1e26c64817c3c0e2b243330154f
https://doi.org/10.1523/jneurosci.5214-03.2004
https://doi.org/10.1523/jneurosci.5214-03.2004
Autor:
David M. Lovinger, Gregory L. Gerdeman
Publikováno v:
British Journal of Pharmacology. 140:781-789
Preparations from the herb Cannabis sativa (such as marijuana, hashish and bhang) have been used across numerous cultures for thousands of years, and it is reasonable to say that this impressive history of use can be attributed in large part to profo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d70a4a37e17bda66344684480d59628
https://doi.org/10.1038/sj.bjp.0705466
https://doi.org/10.1038/sj.bjp.0705466
Publikováno v:
Trends in Neurosciences. 26:184-192
Drug addiction can take control of the brain and behavior, activating behavioral patterns that are directed excessively and compulsively toward drug usage. Such patterns often involve the development of repetitive and nearly automatic behaviors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bff578e63c7e0fe6b2a082f11403908
https://doi.org/10.1016/s0166-2236(03)00065-1
https://doi.org/10.1016/s0166-2236(03)00065-1
Autor:
Gregory L. Gerdeman, David M. Lovinger
Publikováno v:
Journal of Neurophysiology. 85:468-471
CB1 cannabinoid receptors in the neostriatum mediate profound motor deficits induced when cannabinoid drugs are administered to rodents. Because the CB1 receptor has been shown to inhibit neurotransmitter release in various brain areas, we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833d05bb58531664cd84add8562c7a62
https://doi.org/10.1152/jn.2001.85.1.468
https://doi.org/10.1152/jn.2001.85.1.468
Publikováno v:
European journal of applied physiology. 113(4)
Endocannabinoids (eCB) are endogenous ligands for cannabinoid receptors that are densely expressed in brain networks responsible for reward. Recent work shows that exercise activates the eCB system in humans and other mammals, suggesting eCBs are par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8249d3e4df60a08f924a0da654ee7a
https://pubmed.ncbi.nlm.nih.gov/22990628
https://pubmed.ncbi.nlm.nih.gov/22990628
Publikováno v:
Cannabinoids and the Brain ISBN: 9780387743486
Multiple lines of evidence indicate a prominent role for the cannabinoid signaling system in the control of basal ganglia function, exerted by modulating the activity of various classic neurotransmitters, such as GABA, dopamine, or glutamate, that op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55ad21a2af2c06e8b5005b33f5a7f5d
https://doi.org/10.1007/978-0-387-74349-3_21
https://doi.org/10.1007/978-0-387-74349-3_21
Autor:
Gregory L. Gerdeman
Publikováno v:
Cannabinoids and the Brain ISBN: 9780387743486
In the study of synaptic transmission, the field of endocannabinoid research is flowering. A wealth of recent findings has revealed critical molecular underpinnings of endocannabinoid generation and signal transduction, and the subcellular localizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23e9df9bf8d0229b1f1a2b2c1539c353
https://doi.org/10.1007/978-0-387-74349-3_11
https://doi.org/10.1007/978-0-387-74349-3_11