Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gregory L. Bennett"'
Autor:
Frederic J. de Sauvage, Mark Nagel, Philip E. Hass, Gilbert-Andre Keller, Eric Stefanich, Dan L. Eaton, Ramon Widmer, Gregory L. Bennett, Paul J. Fielder
Publikováno v:
Blood. 89:2782-2788
Recent studies have shown that plasma thrombopoietin (TPO) levels appear to be directly regulated by platelet mass and that removal of plasma TPO by platelets via binding to the c-Mpl receptor is involved in the clearance of TPO in rodents. To help e
Human Hepatocyte Growth Factor in Alcoholic Liver Disease: A Comparison with Change in α-Fetoprotein
Autor:
Susan D. Rouster, Charles J. Grossman, John R. Lake, Thomas E. Moritz, Antonio Chedid, Filip Roos, Gregory L. Bennett, Charles L. Mendenhall, Gary A. Roselle
Publikováno v:
Alcoholism: Clinical and Experimental Research. 20:1625-1630
To evaluate the hepatic regenerative response in patients with alcoholic liver disease, sera from 263 patients with severe alcoholic hepatitis and/or cirrhosis were analyzed for hepatocyte growth factor (HGF) and alpha-fetoprotein (AFP). HGF concentr
Autor:
Manisha R. Shah, Steven K. Baker, Richard M. Pope, Catherine J. Haskell, Ralph J. Panos, Shigeru Hosaka, Margaret M. Halloran, Gregory L. Bennett, G. Kenneth Haines, Alisa E. Koch, Napoleone Ferrara
Publikováno v:
Arthritis & Rheumatism. 39:1566-1575
Objective. Angiogenesis is an integral component of the vasculoproliferative phase of rheumatoid arthritis (RA). Recently, a heparin-binding cytokine termed hepatocyte growth factor (HGF), or scatter factor (due to its ability to disperse cohesive ep
Autor:
Ian C. McKay, Kenneth J. Hillan, R.N.M. MacSween, Rod K. Ferrier, George L. A. Bird, Gregory L. Bennett, Martin C. Logan
Publikováno v:
Journal of Hepatology. 24:385-390
Hepatocyte growth factor is thought to be important in stimulating growth of the liver following injury. In this study we have measured serum levels of hepatocyte growth factor together with hepatocyte proliferation in liver biopsies, by detection of
Autor:
Kathleen L. King, Ralph H. Schwall, Ling Chang, Gregory L. Bennett, Steven M. Chamow, Peter Fugedi, Louise Richardson, Jun Liu, Thomas F. Zioncheck, Robert J. Stack
Publikováno v:
Journal of Biological Chemistry. 270:16871-16878
Hepatocyte growth factor (HGF) is a potent mitogen, motogen, and morphogen for various epithelial cell types. The pleiotropic effects of HGF are mediated by its binding to a specific high affinity receptor, c-Met. In addition, HGF binds to heparan su
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 268:G380-G386
Hepatocyte growth factor/scatter factor (HGF/SF) is a potent stimulator of DNA synthesis in a variety of epithelial cells, including hepatocytes, and has been implicated in liver regeneration. We show here that combining dextran sulfate with HGF/SF m
Autor:
William Mallet, Suzanna Clark, Michelle G. Schweiger, Ben-Quan Shen, Margaret Kenrick, Cinthia V. Pastuskovas, Gregory L. Bennett, Paul J. Fielder, Marjie Van Hoy, Leslie A. Khawli, Jay Tibbitts, Siao Ping Tsai, Mohammed Majidy, Sarajane Ross
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 38(12)
3A5 is a novel antibody that binds repeated epitopes within CA125, an ovarian tumor antigen that is shed into the circulation. Binding to shed antigen may limit the effectiveness of therapeutic antibodies because of unproductive immune complex (IC) f
Publikováno v:
Journal of Biological Chemistry. 267:16283-16287
Interleukin 8 (IL-8) and melanocyte growth-stimulatory activity/gro (MGSA) are structurally related proinflammatory cytokines that are chemoattractants and activators of neutrophils. Recently, cDNA clones encoding a high affinity IL-8 receptor (IL-8R
Autor:
John Burnier, Gregory L. Bennett, F. de Sauvage, David V. Goeddel, Clifford Quan, Richard Horuk
Publikováno v:
Journal of Biological Chemistry. 267:6479-6482
We report here the molecular characterization of a recombinant cell line (293-STaR) expressing the heat-stable enterotoxin receptor (STaR) from human intestine. We have compared the 293-STaR cell line with the human colonic cell line T84 that endogen
Autor:
Brian D. Bennett, Gregory L. Bennett, William J. Henzel, R. V. Vitangcol, J. R. S. Jewett, David G. Lowe, John Burnier
Publikováno v:
Journal of Biological Chemistry. 266:23060-23067
The natriuretic peptide receptors (NPRs) are a family of three cell surface glycoproteins, each with a single transmembrane domain. Two of these receptors, designated NPR-A and NPR-B, are membrane guanylyl cyclases that synthesize cGMP in response to