Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gregory L Adams"'
Autor:
Gregory L. Adams, Parul S. Pall, Steven M. Grauer, Xiaoping Zhou, Jeanine E. Ballard, Marissa Vavrek, Richard L. Kraus, Pierre Morissette, Nianyu Li, Stefania Colarusso, Elisabetta Bianchi, Anandan Palani, Rebecca Klein, Christopher T. John, Deping Wang, Matthew Tudor, Andrew F. Nolting, Mirlinda Biba, Timothy Nowak, Alexey A. Makarov, Mikhail Reibarkh, Alexei V. Buevich, Wendy Zhong, Erik L. Regalado, Xiao Wang, Qi Gao, Aurash Shahripour, Yuping Zhu, Daniele de Simone, Tommaso Frattarelli, Nicolo’ Maria Pasquini, Paola Magotti, Roberto Iaccarino, Yuxing Li, Kelli Solly, Keun-Joong Lee, Weixun Wang, Feifei Chen, Haoyu Zeng, Jixin Wang, Hilary Regan, Rupesh P. Amin, Christopher P. Regan, Christopher S. Burgey, Darrell A. Henze, Chengzao Sun, David M. Tellers
Publikováno v:
Journal of Medicinal Chemistry. 65:485-496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ecd04283fe1d38ba43c9ca77818a20e
https://doi.org/10.1021/acs.jmedchem.1c01570
https://doi.org/10.1021/acs.jmedchem.1c01570
Autor:
Viktor Pisarenko, Anja Muzdalo, Danny A. Bitton, Petr Mejzlik, Gregory L. Adams, Meir Glick, Kamila Clarova, Esteban Jenkins, Dzianis Hancharyk, Javier L. Baylon, Anna Gromek, Martin Spale, David Bednar, Charlie Chang, Anne Mai Wassermann, Oleg Ursu
Publikováno v:
Journal of chemical information and modeling. 62(5)
Therapeutic peptides offer potential advantages over small molecules in terms of selectivity, affinity, and their ability to target “undruggable” proteins that are associated with a wide range of pathologies. Despite their importance, there are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ab84df102f573fd0b02fb2bc1cb63e
https://pubmed.ncbi.nlm.nih.gov/35192366
https://pubmed.ncbi.nlm.nih.gov/35192366
Autor:
Gregory L, Adams, Parul S, Pall, Steven M, Grauer, Xiaoping, Zhou, Jeanine E, Ballard, Marissa, Vavrek, Richard L, Kraus, Pierre, Morissette, Nianyu, Li, Stefania, Colarusso, Elisabetta, Bianchi, Anandan, Palani, Rebecca, Klein, Christopher T, John, Deping, Wang, Matthew, Tudor, Andrew F, Nolting, Mirlinda, Biba, Timothy, Nowak, Alexey A, Makarov, Mikhail, Reibarkh, Alexei V, Buevich, Wendy, Zhong, Erik L, Regalado, Xiao, Wang, Qi, Gao, Aurash, Shahripour, Yuping, Zhu, Daniele, de Simone, Tommaso, Frattarelli, Nicolo' Maria, Pasquini, Paola, Magotti, Roberto, Iaccarino, Yuxing, Li, Kelli, Solly, Keun-Joong, Lee, Weixun, Wang, Feifei, Chen, Haoyu, Zeng, Jixin, Wang, Hilary, Regan, Rupesh P, Amin, Christopher P, Regan, Christopher S, Burgey, Darrell A, Henze, Chengzao, Sun, David M, Tellers
Publikováno v:
Journal of medicinal chemistry. 65(1)
Inhibitor cystine knot peptides, derived from venom, have evolved to block ion channel function but are often toxic when dosed at pharmacologically relevant levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f03f2c5f5119ec1a76291dcc4081ccf8
https://pubmed.ncbi.nlm.nih.gov/34931831
https://pubmed.ncbi.nlm.nih.gov/34931831
Autor:
Melissa Kirkland, M A Powles, Francisco Velazquez, Eric R. Ashley, Nengxue Wang, Shah Unmesh G, Feroze Ujjainwalla, Taro E. Akiyama, Eric J. Gilbert, Charles Lee Jayne, Michele Pachanski, Dan Zhou, Scott D. Edmondson, Jerry Di Salvo, Andreas Verras, Maria Madeira, Takao Suzuki, Srikanth Venkatraman, Quang Truong, Wu Yin, Gregory L. Adams, Shouwu Miao
Publikováno v:
ACS Medicinal Chemistry Letters. 8:96-101
GPR120 (FFAR4) is a fatty acid sensing G protein coupled receptor (GPCR) that has been identified as a target for possible treatment of type 2 diabetes. A selective activator of GPR120 containing a chromane scaffold has been designed, synthesized, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c4bd187bc901f79299111d7c132c57
https://doi.org/10.1021/acsmedchemlett.6b00394
https://doi.org/10.1021/acsmedchemlett.6b00394
The voltage-gated sodium channel Nav1.7 is being heavily pursued as a potential target for the treatment of pain based upon strong human genetic validation. A safe and effective Nav1.7 targeting molecule would require appropriate selectivity over mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0a8a2aeb2db3d5801de0dcf6c94a40a
https://doi.org/10.1039/9781788011532-00411
https://doi.org/10.1039/9781788011532-00411
Autor:
Gregory L, Adams, Francisco, Velazquez, Charles, Jayne, Unmesh, Shah, Shouwu, Miao, Eric R, Ashley, Maria, Madeira, Taro E, Akiyama, Jerry, Di Salvo, Takao, Suzuki, Nengxue, Wang, Quang, Truong, Eric, Gilbert, Dan, Zhou, Andreas, Verras, Melissa, Kirkland, Michele, Pachanski, Maryann, Powles, Wu, Yin, Feroze, Ujjainwalla, Srikanth, Venkatraman, Scott D, Edmondson
Publikováno v:
ACS medicinal chemistry letters. 8(1)
GPR120 (FFAR4) is a fatty acid sensing G protein coupled receptor (GPCR) that has been identified as a target for possible treatment of type 2 diabetes. A selective activator of GPR120 containing a chromane scaffold has been designed, synthesized, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b516664a4a45395b9f909635d7176636
https://pubmed.ncbi.nlm.nih.gov/28105282
https://pubmed.ncbi.nlm.nih.gov/28105282
Autor:
Gregory L, Adams, Amos B, Smith
Publikováno v:
The Alkaloids. Chemistry and biology. 76
An update on the literature covering the akuammiline family of alkaloids is presented. This chapter begins with a summary of new akuammiline alkaloids reported since 2000 and is followed by an overview of new reported bioactivities of akuammiline alk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b66a08e3dd113b2ce316f5d838ee2e1
https://pubmed.ncbi.nlm.nih.gov/26827884
https://pubmed.ncbi.nlm.nih.gov/26827884
Publikováno v:
Journal of Business Ethics. 99:565-585
Extending the dialogue on corporate social performance (CSP) as descriptive stakeholder management (Clarkson, Acad Manage Rev 20:92, 1995), we examine differences in CSP activity between family and nonfamily firms. We argue that CSP activity can be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1162a317ca4655e54a2b32762bec9e21
https://doi.org/10.1007/s10551-010-0669-9
https://doi.org/10.1007/s10551-010-0669-9
Publikováno v:
journal of Real Estate Research. 29(2):115-136
This study of real estate investment trusts (REITs) analyzes three possible explanations for the stock price reaction to a repurchase announcement and the subsequent repurchase behavior of managers under each hypothesis. Two of the hypotheses, the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f267e2842e8d0f47dd53dda85ff4969d
http://pages.jh.edu/jrer/papers/pdf/past/vol29n02/01.115_136.pdf
http://pages.jh.edu/jrer/papers/pdf/past/vol29n02/01.115_136.pdf
Autor:
Angela L Ngai, Gregory L Adams, Guanghan Liu, Ginamarie Foglia, Michael Leonardi, Jon E. Stek, Gary S. Marshall, Maria Petrecz, Andrew W. Lee, Sheryl Flores, Jin Xu
Publikováno v:
Pediatrics. 136(2)
BACKGROUND: DTaP5-IPV-Hib-HepB is a fully liquid investigational hexavalent vaccine directed against 6 diseases. METHODS: This multicenter, open-label, comparator-controlled, phase III study randomly assigned healthy infants 2-to-1 as follows: group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad44c1b92decee8b5cd3e13ef5abf16
https://pubmed.ncbi.nlm.nih.gov/26216331
https://pubmed.ncbi.nlm.nih.gov/26216331