Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gregory Koval"'
Autor:
Meir Wetzler, Dorothy Watson, Wendy Stock, Gregory Koval, Flora A. Mulkey, Eva E. Hoke, John M. McCarty, William G. Blum, Bayard L. Powell, Guido Marcucci, Clara D. Bloomfield, Charles A. Linker, Richard A. Larson
Publikováno v:
Haematologica, Vol 99, Iss 1 (2014)
Allogeneic stem cell transplantation is the standard approach to Philadelphia chromosome positive acute lymphoblastic leukemia. We hypothesized that imatinib plus sequential chemotherapy will result in significant leukemia cell cytoreduction in patie
Externí odkaz:
https://doaj.org/article/f1cbe4d8ef7e4d019cf9b9357751be77
Autor:
Meir Wetzler, Wendy Stock, Bayard L. Powell, William Blum, Eva Hoke, Clara D. Bloomfield, Guido Marcucci, Dorothy Watson, Richard A. Larson, Gregory Koval, Flora Mulkey, John M. McCarty, Charles A. Linker
Publikováno v:
Haematologica. 99:111-115
Allogeneic stem cell transplantation is the standard approach to Philadelphia chromosome positive acute lymphoblastic leukemia. We hypothesized that imatinib plus sequential chemotherapy will result in significant leukemia cell cytoreduction in patie
Autor:
Flora Mulkey, Clara D. Bloomfield, Guido Marcucci, Charles G. Mullighan, Richard Stone, Gregory Koval, Wendy Stock, Meir Wetzler, Richard A. Larson, Steven M. Devine, Rebecca DeBoer, Susan Geyer
Publikováno v:
Leukemialymphoma. 57(10)
Recent studies have identified oncogenic lesions in Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) and ABL1 kinase mutations that confer resistance to tyrosine kinase inhibitors. We sought to determine the prevalence and cl
Autor:
Gregory Koval, Mark J. Ratain, Richard A. Larson, Lucy A. Godley, Karen W.L. Yee, Anna B. Halpern, Noreen Fulton, Margaret Green, Meghan Bennett, Olatoyosi Odenike, Ryan J. Mattison, Wendy Stock, Jozef Madzo, Gregory Malnassy, Theodore Karrison
Background We hypothesized that targeting two mechanisms of epigenetic silencing would be additive or synergistic with regard to expression of specific target genes. The primary objective of the study was to establish the maximum tolerated dose (MTD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b39b7f144d149592b871d326b89020
https://europepmc.org/articles/PMC4390421/
https://europepmc.org/articles/PMC4390421/
Autor:
Olatoyosi Odenike, Richard A. Larson, Xavier Poiré, Poluru L. Reddy, Philip A. Dy, Wendy Stock, Walter M. Stadler, Kevin Shannon, Loren Joseph, Scott E. Smith, Ernesto Diaz-Flores, Emily Curran, Gregory Koval, Neil M. Iyengar, Sachdev P. Thomas, Mark Kirschbaum, Harry P. Erba, Ehab Atallah, Rangesh Kunnavakkam, Leslie Popplewell, Nitin Jain, Margaret Green, Austin Doyle, Theodore Karrison
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 20, iss 2
Purpose: The clinical relevance of targeting the RAS/RAF/MEK/ERK pathway, activated in 70% to 80% of patients with acute myelogenous leukemia (AML), is unknown. Experimental Design: Selumetinib is an oral small-molecule inhibitor of MAP–ERK kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c854599100d5b1a4d55d5fab45f91b71
https://escholarship.org/uc/item/5tw6j407
https://escholarship.org/uc/item/5tw6j407
Autor:
Gregory Koval, Frederick R. Appelbaum, Barry K. Moser, Martin S. Tallman, Nicholas Holowka, Robert E. Gallagher, Dorie Sher, Wendy Stock, Richard A. Larson, Kabir Gulati, Xavier Poiré, Clara D. Bloomfield, Bayard L. Powell, Elisabeth Paietta, Kristina Laumann, Cheryl L. Willman
Publikováno v:
Leukemialymphoma. 55(7)
The addition of arsenic trioxide (ATO) to frontline therapy of acute promyelocytic leukemia (APL) has been shown to result in significant improvements in disease-free survival (DFS). FLT3 mutations are frequently observed in APL, but its prognostic s
Autor:
Bayard L. Powell, Guido Marcucci, Wendy Stock, Meir Wetzler, Gregory Koval, Eva Hoke, Richard A. Larson, William Blum, John M. McCarty, Charles A. Linker, Clara D. Bloomfield, Kouros Owzar, Dorothy Watson
Publikováno v:
Blood. 120:816-816
Abstract 816 We hypothesized that imatinib plus sequential chemotherapy would result in significant leukemia cell cytoreduction (molecular remission) in patients with Ph+ acute lymphoblastic leukemia (ALL), allowing collection of normal hematopoietic
Autor:
Clara D. Bloomfield, Kouros Owzar, Dorie Sher, Gregory Malnassy, Wendy Stock, Gregory Koval, Richard A. Larson, Meir Wetzler, Dorothy Watson
Publikováno v:
Blood. 118:2541-2541
Abstract 2541 CALGB 10001 tested the feasibility of performing allogeneic or autologous stem cell transplantation (SCT) following combination chemotherapy and tyrosine kinase inhibition with imatinib in patients Disclosures: No relevant conflicts of