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Autor:
Gregory Keil
Publikováno v:
Pharmaceutical Bioprocessing. 3:371-380
Generation of recombinant therapeutic proteins involves the use of Chinese hamster ovary cells as one of the workhorses for complex protein production. This process requires screening large numbers of transfected cells to identify single clones that
Autor:
Gregory Keil, Nikita Jhaveri, Zhong Liu, Russell G. G. Condon, Yung-Shyeng Tsao, Aaron S. Meyer
Publikováno v:
Biotechnology progress. 28(1)
In bioprocess development, the 96-well plate format has been widely used for high-throughput screening of production cell line or culture conditions. However, suspension cell cultures in conventional 96-well plates often fail to reach high cell densi