Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gregory K.W. Lam"'
Publikováno v:
Drug Discovery Today: Disease Mechanisms. 1:53-58
The availability of competent functional bone marrow-derived nucleated cells, such as endothelial progenitor cells (EPCs) capable of repair plays a determinant role in atherosclerosis genesis. In the presence of traditional risk factors for coronary
Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide
Autor:
Christopher D. Kontos, Asif Ahmed, Jianhua Huang, Xi-Lin Niu, Peter W. Hewett, Rahul Potluri, Takeshi Fujisawa, Kunal Chudasama, Melissa J. Cudmore, Bahjat Al-Ani, Clarence M. Findley, Allyah Abbas, Shakil Ahmad, Vineet Bhandari, Gregory K.W. Lam
Publikováno v:
Ahmed, A, Fujisawa, T, Niu, X-L, Ahmad, S, Al-Ani, B, Chudasama, K, Abbas, A, Potluri, R, Bhandari, V, Findley, C M, Lam, G K W, Huang, J, Hewett, P W, Cudmore, M & Kontos, C D 2009, ' Angiopoietin-2 confers Atheroprotection in apoE-/-mice by inhibiting LDL oxidation via nitric oxide ', Circulation Research, vol. 104, no. 12, pp. 1333-6 . https://doi.org/10.1161/CIRCRESAHA.109.196154
Atherosclerosis is promoted by a combination of hypercholesterolemia and vascular inflammation. The function of Angiopoietin (Ang)-2, a key regulator of angiogenesis, in the maintenance of large vessels is unknown. A single systemic administration of
Autor:
Christopher D. Kontos, Emily L. Messina, Howard A. Rockman, Dawn E. Bowles, Joshua M. Hare, Jonathan S. Stamler, Liang Xie, Nestor Villamizar, Jeffrey Nienaber, Brian Lima, Diana L. Diesen, Gregory K.W. Lam
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(15)
Despite substantial evidence that nitric oxide (NO) and/or endogenous S -nitrosothiols (SNOs) exert protective effects in a variety of cardiovascular diseases, the molecular details are largely unknown. Here we show that following left coronary arter
Response to Letter Regarding Article 'Atherosclerosis 2005: Recent Discoveries and Novel Hypotheses'
Autor:
Pascal J. Goldschmidt-Clermont, Douglas W. Losordo, Mark A. Creager, Victor J. Dzau, Momtaz Wassef, Gregory K.W. Lam, Joanne Kurtzberg, Chunming Dong
Publikováno v:
Circulation. 113
We thank Drs Williams and Tabas for their interest in our work1 and agree that there is a substantial body of evidence supporting the role of hyperlipidemia in atherogenesis. In our review, we addressed this point and indicated that cholesterol may b