Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gregory John Russell-Jones"'
Publikováno v:
Journal of Drug Targeting. 19:133-139
Many different cancer types have previously been found to show increased uptake of the vitamins folate, vitamin B12, and biotin; however, it is not known whether these tumor lines show increased uptake of one or more of the vitamins. The current stud
Autor:
Kirsten McTavish, David Nowotnik, John R. Rice, John Fergus Mcewan, Gregory John Russell-Jones
Publikováno v:
Journal of Inorganic Biochemistry. 98:1625-1633
Targeted chemotherapy for cancer treatment offers a great potential advantage in tumour treatment due to greater specificity of delivery which leads to increased dose of the cytotoxin delivered to the tumour relative to the rest of the body. In order
Autor:
Habberfield Alan D, Kathleen Jensen-Pippo, Lloyd D. Ralph, Steven William Westwood, Gregory John Russell-Jones
Publikováno v:
International Journal of Pharmaceutics. 145:1-8
Proteins are normally very poorly absorbed from the intestine as the intestinal epithelial cells act as a barrier to the uptake of all but the smallest of molecules. We have used the natural uptake mechanism for Vitamin B 12 (VB 12 ) to increase the
Autor:
Prakash V. Diwan, Kishore B. Chalasani, Sarath K. Yandrapu, Gregory John Russell-Jones, Sanjay Jain
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 117(3)
In spite of great potential, effective oral delivery of many vitamin B 12 -peptide/protein drug conjugates does not occur due to the limited uptake capacity of the VB 12 transport system, loss of bioactivity of native protein and/or intrinsic factor
Publikováno v:
The Journal of Experimental Medicine
Oral immunization of an animal is generally hard to achieve unless large quantities of antigen are administered. In this study a number of antigens were tested for their ability to elicit a systemic immune response upon oral administration. It was fo