Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Gregory J. Quirk"'
Autor:
David Dopfel, Pablo D. Perez, Alexander Verbitsky, Hector Bravo-Rivera, Yuncong Ma, Gregory J. Quirk, Nanyin Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTS
Externí odkaz:
https://doaj.org/article/4333c50c454e4bad9388d3e0dbe266ec
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
The long-lasting nature of fear memories is essential for survival, but the neural circuitry for retrieval of these associations changes with the passage of time. We previously reported a time-dependent shift from prefrontal-amygdalar circuits to pre
Externí odkaz:
https://doaj.org/article/cd01e26bb6d34480a88abd573a1801c1
Autor:
Hector Bravo-Rivera, Patricia Rubio Arzola, Albit Caban-Murillo, Adriana N. Vélez-Avilés, Shantée N. Ayala-Rosario, Gregory J. Quirk
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The ability of animals to maximize benefits and minimize costs during approach-avoidance conflicts is an important evolutionary tool, but little is known about the emergence of specific strategies for conflict resolution. Accordingly, we developed a
Externí odkaz:
https://doaj.org/article/e7ade176c91b482fadf1cc228a1a5399
Autor:
Henry W. Chase, Simona Graur, Amelia Versace, Tsafrir Greenberg, Lisa Bonar, Robert Hudak, Gregory J. Quirk, Ben D. Greenberg, Steven A. Rasmussen, Suzanne N. Haber, Mary L. Phillips
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102404- (2020)
Obsessive-Compulsive Disorder (OCD) is characterized by repetitive avoidance behavior which is distressing and associated with marked impairment of everyday life. Recently, paradigms have been designed to explore the hypothesis that avoidance behavio
Externí odkaz:
https://doaj.org/article/2e860d2043c74a45b74647af592ca67c
Autor:
Denis Paré, Gregory J. Quirk
Publikováno v:
npj Science of Learning, Vol 2, Iss 1, Pp 1-8 (2017)
Abstract For the past 30 years, research on the amygdala has largely focused on the genesis of defensive behaviors as its main function. This focus originated from early lesion studies and was supported by extensive anatomical, physiological, and pha
Externí odkaz:
https://doaj.org/article/80aec71591994bf0a9066723f71bf2da
Autor:
Maria M Diehl, Jorge M Iravedra-Garcia, Jonathan Morán-Sierra, Gabriel Rojas-Bowe, Fabiola N Gonzalez-Diaz, Viviana P Valentín-Valentín, Gregory J Quirk
Publikováno v:
eLife, Vol 9 (2020)
The prefrontal cortex (PFC) integrates incoming information to guide our actions. When motivation for food-seeking competes with avoidance of danger, the PFC likely plays a role in selecting the optimal choice. In platform-mediated active avoidance,
Externí odkaz:
https://doaj.org/article/4f9bc01abca84930a5df62adbae79021
Autor:
Ana Silva, Keerthana Iyer, Francesca Cirulli, Elaine Del-Bel, Zulma Dueñas, Edna Matta-Camacho, José Luis Peña, Gregory J. Quirk, Valeria Ramirez-Castañeda, Carmen Sandi
Publikováno v:
Nature Neuroscience. 25:1115-1118
Although issues surrounding diversity and inclusion in science are global, distinctive region-specific socioeconomic factors and operational biases interact to widen the opportunity gap and exacerbate the isolation of specific groups of disadvantaged
Autor:
Maria M Diehl, Christian Bravo-Rivera, Jose Rodriguez-Romaguera, Pablo A Pagan-Rivera, Anthony Burgos-Robles, Ciorana Roman-Ortiz, Gregory J Quirk
Publikováno v:
eLife, Vol 7 (2018)
Much is known about the neural circuits of conditioned fear and its relevance to understanding anxiety disorders, but less is known about other anxiety-related behaviors such as active avoidance. Using a tone-signaled, platform-mediated avoidance tas
Externí odkaz:
https://doaj.org/article/0db327a97b524845bc0a6231aa4f45e6
Autor:
Steven A. Rasmussen, João Paulo Lima Santos, Anastasia Yendiki, Benjamin D. Greenberg, E. Kale Edmiston, Robert Hudak, Richelle Stiffler, Zhiqiang Sha, Suzanne N. Haber, Hesheng Liu, Tsafrir Greenberg, Mary L. Phillips, Lisa Bonar, Henry W. Chase, Gregory J. Quirk, Simona Graur, Amelia Versace, Jay C. Fournier
Publikováno v:
Biol Psychiatry Cogn Neurosci Neuroimaging
Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive, compulsive behaviors. Neuroimaging studies have implicated altered connectivity among the functional networks of the cerebral cortex in the pathophysiology of