Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gregory J. Krause"'
Autor:
Gregory J. Krause, Philipp Kirchner, Barbara Stiller, Kateryna Morozova, Antonio Diaz, Kuei-Ho Chen, Nevan J. Krogan, Esperanza Agullo-Pascual, Cristina C. Clement, Kristen Lindenau, Danielle L. Swaney, Shilpa Dilipkumar, Jose Javier Bravo-Cordero, Laura Santambrogio, Ana Maria Cuervo
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113529- (2023)
Summary: Chaperone-mediated autophagy (CMA) and endosomal microautophagy (eMI) are pathways for selective degradation of cytosolic proteins in lysosomes and late endosomes, respectively. These autophagic processes share as a first step the recognitio
Externí odkaz:
https://doaj.org/article/d2a335d99ba9457284f584165e90233a
Autor:
Hyun ah Yoon, Rachel Bartash, Inessa Gendlina, Johanna Rivera, Antonio Nakouzi, Robert H. Bortz III, Ariel S. Wirchnianski, Monika Paroder, Karen Fehn, Leana Serrano-Rahman, Rachelle Babb, Uzma N. Sarwar, Denise Haslwanter, Ethan Laudermilch, Catalina Florez, M. Eugenia Dieterle, Rohit K. Jangra, J. Maximilian Fels, Karen Tong, Margarette C. Mariano, Olivia Vergnolle, George I. Georgiev, Natalia G. Herrera, Ryan J. Malonis, Jose A. Quiroz, Nicholas C. Morano, Gregory J. Krause, Joseph M. Sweeney, Kelsie Cowman, Stephanie Allen, Jayabhargav Annam, Ariella Applebaum, Daniel Barboto, Ahmed Khokhar, Brianna J. Lally, Audrey Lee, Max Lee, Avinash Malaviya, Reise Sample, Xiuyi A. Yang, Yang Li, Rafael Ruiz, Raja Thota, Jason Barnhill, Doctor Y. Goldstein, Joan Uehlinger, Scott J. Garforth, Steven C. Almo, Jonathan R. Lai, Morayma Reyes Gil, Amy S. Fox, Kartik Chandran, Tao Wang, Johanna P. Daily, Liise-anne Pirofski
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
Convalescent plasma with severe acute respiratory disease coronavirus 2 (SARS-CoV-2) antibodies (CCP) may hold promise as a treatment for coronavirus disease 2019 (COVID-19). We compared the mortality and clinical outcome of patients with COVID-19 wh
Externí odkaz:
https://doaj.org/article/0358cbc15a254f3fab654810aaab2594
Autor:
Joseph M. Sweeney, Mohammad Barouqa, Gregory J. Krause, Jesus D. Gonzalez-Lugo, Shafia Rahman, Morayma Reyes Gil
Publikováno v:
TH Open, Vol 05, Iss 01, Pp e89-e103 (2021)
The causes of coagulopathy associated with coronavirus disease 2019 (COVID-19) are poorly understood. We aimed to investigate the relationship between von Willebrand factor (VWF) biomarkers, intravascular hemolysis, coagulation, and organ damage in C
Externí odkaz:
https://doaj.org/article/feaf5bece3944db8864d637c9451297b
Autor:
Yves R. Juste, Susmita Kaushik, Mathieu Bourdenx, Ranee Aflakpui, Sanmay Bandyopadhyay, Fernando Garcia, Antonio Diaz, Kristen Lindenau, Vincent Tu, Gregory J. Krause, Maryam Jafari, Rajat Singh, Javier Muñoz, Fernando Macian, Ana Maria Cuervo
Publikováno v:
Nature Cell Biology. 23:1255-1270
Circadian rhythms align physiological functions with the light-dark cycle through oscillatory changes in the abundance of proteins in the clock transcriptional programme. Timely removal of these proteins by different proteolytic systems is essential
Autor:
Gregory J. Krause, Antonio Diaz, Maryam Jafari, Rabia R. Khawaja, Esperanza Agullo‐Pascual, Olaya Santiago‐Fernández, Alicia L. Richards, Kuei‐Ho Chen, Phillip Dmitriev, Yan Sun, Stephanie K. See, Kotb Abdelmohsen, Krystyna Mazan‐Mamczarz, Nevan J. Krogan, Myriam Gorospe, Danielle L. Swaney, Simone Sidoli, Jose Javier Bravo‐Cordero, Martin Kampmann, Ana Maria Cuervo
Publikováno v:
Aging cell. 21(10)
Autophagy is essential for protein quality control and regulation of the functional proteome. Failure of autophagy pathways with age contributes to loss of proteostasis in aged organisms and accelerates the progression of age-related diseases. In thi
Autor:
Julio Madrigal-Matute, Jenny de Bruijn, Kim van Kuijk, Dario F. Riascos-Bernal, Antonio Diaz, Inmaculada Tasset, Adrián Martín-Segura, Marion J. J. Gijbels, Bianca Sander, Susmita Kaushik, Erik A. L. Biessen, Simoni Tiano, Mathieu Bourdenx, Gregory J. Krause, Ian McCracken, Andrew H. Baker, Han Jin, Nicholas E. S. Sibinga, Jose Javier Bravo-Cordero, Fernando Macian, Rajat Singh, Patrick C. N. Rensen, Jimmy F. P. Berbée, Gerard Pasterkamp, Judith C. Sluimer, Ana Maria Cuervo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 119(14), e2121133119 (2022). doi:10.1073/pnas.2121133119
Proceedings of the National Academy of Sciences, 119(14). NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America, 119(14):2121133119. National Academy of Sciences
Madrigal-Matute, J, de Bruijn, J, van Kuijk, K, Riascos-Bernal, D F, Diaz, A, Tasset, I, Martín-Segura, A, J.J. Gijbel, M, Sander, B, Kaushik, S, Biessen, E A L, Tiano, S, Bourdenx, M, J. Krause, G, McCracken, I, Baker, A H, Han, J, Sibinga, N, Bravo-Cordero, J J, Macian, F, Singh, R, Rensen, P C N, Berbée, J F P, Pasterkamp, G, Sluimer, J & Cuervo, A M 2022, ' Protective role of chaperone-mediated autophagy against atherosclerosis ', Proceedings of the National Academy of Sciences . https://doi.org/10.1073/pnas.2121133119
Proceedings of the National Academy of Sciences of the United States of America, 119(14):e2121133119. National Academy of Sciences
Proceedings of the National Academy of Sciences, 119(14). NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America, 119(14):2121133119. National Academy of Sciences
Madrigal-Matute, J, de Bruijn, J, van Kuijk, K, Riascos-Bernal, D F, Diaz, A, Tasset, I, Martín-Segura, A, J.J. Gijbel, M, Sander, B, Kaushik, S, Biessen, E A L, Tiano, S, Bourdenx, M, J. Krause, G, McCracken, I, Baker, A H, Han, J, Sibinga, N, Bravo-Cordero, J J, Macian, F, Singh, R, Rensen, P C N, Berbée, J F P, Pasterkamp, G, Sluimer, J & Cuervo, A M 2022, ' Protective role of chaperone-mediated autophagy against atherosclerosis ', Proceedings of the National Academy of Sciences . https://doi.org/10.1073/pnas.2121133119
Proceedings of the National Academy of Sciences of the United States of America, 119(14):e2121133119. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America 119(14), e2121133119 (2022). doi:10.1073/pnas.2121133119
Published by National Acad. of Sciences, Washington, DC
Published by National Acad. of Sciences, Washington, DC
Autor:
Angeleen Fleming, Mathieu Bourdenx, Motoki Fujimaki, Cansu Karabiyik, Gregory J. Krause, Ana Lopez, Adrián Martín-Segura, Claudia Puri, Aurora Scrivo, John Skidmore, Sung Min Son, Eleanna Stamatakou, Lidia Wrobel, Ye Zhu, Ana Maria Cuervo, David C. Rubinsztein
Publikováno v:
Neuron
The term autophagy encompasses different pathways that route cytoplasmic material to lysosomes for degradation and includes macroautophagy, chaperone-mediated autophagy, and microautophagy. Since these pathways are crucial for degradation of aggregat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f0ca7304e70bc78cf8c402cc80024c
https://www.repository.cam.ac.uk/handle/1810/335336
https://www.repository.cam.ac.uk/handle/1810/335336
Autor:
Mohammad Barouqa, Jesus D. Gonzalez-Lugo, Joseph M. Sweeney, Morayma Reyes Gil, Gregory J. Krause, Shafia Rahman
Publikováno v:
TH Open, Vol 05, Iss 01, Pp e89-e103 (2021)
TH Open: Companion Journal to Thrombosis and Haemostasis
American Journal of Clinical Pathology
TH Open: Companion Journal to Thrombosis and Haemostasis
American Journal of Clinical Pathology
Systemic inflammation and coagulopathy are characteristic hallmarks of COVID19. “COVID coagulopathy” manifests mainly as a prothrombotic state affecting both large and small blood vessels, and presenting as arterial, venous, and microangiopathic
Autor:
Gregory J. Krause, Ana Maria Cuervo
Publikováno v:
Methods in Cell Biology ISBN: 9780128235447
Methods Cell Biol
Methods Cell Biol
Endosomal microautophagy (eMI) is a type of autophagy that allows for the selective uptake and degradation of cytosolic proteins in late endosome/multi-vesicular bodies (LE/MVB). This process starts with the recognition of a pentapeptide amino acid K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a277909c2058dc3a26148ca4da0657fd
https://doi.org/10.1016/bs.mcb.2020.10.009
https://doi.org/10.1016/bs.mcb.2020.10.009
Autor:
Mohammad Barouqa, Joseph D. Sweeney, Jesus Gonzalez Lugo, Shafia Rahman, Gregory J. Krause, Morayma Reyes Gil
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
The causes of coagulopathy associated with COVID-19 disease are poorly understood. We aimed to investigate the relationship between markers of endothelial activation, intravascular hemolysis, coagulation, and organ damage in COVID-19 patients and stu