Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gregory J. Fredericks"'
Autor:
Gregory J. Fredericks, FuKun W. Hoffmann, Robert J. Hondal, Sharon Rozovsky, Johann Urschitz, Peter R. Hoffmann
Publikováno v:
Antioxidants, Vol 7, Iss 1, p 4 (2017)
Selenoprotein K (SELENOK) is a selenocysteine (Sec)-containing protein localized in the endoplasmic reticulum (ER) membrane where it interacts with the DHHC6 (where single letter symbols represent Asp-His-His-Cys amino acids) enzyme to promote protei
Externí odkaz:
https://doaj.org/article/b13ec90a8b6843b28e46bbdf45a5661c
Autor:
Peter R. Hoffmann, Zhi Huang, FuKun W. Hoffmann, Robert L. Norton, Jeffrey D. Fay, Gregory J. Fredericks
Publikováno v:
Journal of Leukocyte Biology. 101:439-448
Effective activation of macrophages through phagocytic Fcγ receptors (FcγR) has been shown to require selenoprotein K (Selk). We set out to determine whether the FcγR-mediated uptake process itself also requires Selk and potential underlying mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ee6d9ec10ee1107795da75a2f99d9c
https://doi.org/10.1189/jlb.2a0316-156rr
https://doi.org/10.1189/jlb.2a0316-156rr
Publikováno v:
Antioxidants & Redox Signaling. 23:854-862
Significance: Selenoprotein K (SelK) is an endoplasmic reticulum (ER) membrane protein, and its expression is sensitive to dietary selenium levels. A recently described role for SelK as a cofactor in catalyzing protein palmitoylation reactions provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8439b4bc081dd1ff206af7f7c96eaf
https://doi.org/10.1089/ars.2015.6375
https://doi.org/10.1089/ars.2015.6375
Autor:
Tracy Flynn, Jordan E. Pinsker, Debora Chan, Michael Ponaman, Kevin Walker, Gregory J Fredericks, Anita M. Pedersen, David F. Crudo, Jason Barnhill, Christopher Naun, Angela A. Hsu, Kelley von Elten
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 97:E1830-E1835
The cortisol stress response to sedation and anesthesia in children is not well characterized. It is not clear whether it is necessary to give stress doses of corticosteroids to children with adrenal insufficiency undergoing sedated procedures.Our ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3459fde7599f2977bfc816316495cf4b
https://doi.org/10.1210/jc.2012-1499
https://doi.org/10.1210/jc.2012-1499
Autor:
Eludrizza Tabisola-Nuesca, Jordan E. Pinsker, Minela Fernandez-Aponte, Merrily Poth, Debora Chan, Dean R Focht, Deborah Ondrasik, Gregory J Fredericks
Publikováno v:
Pediatric Research. 69:517-521
Ghrelin, an enteric hormone with potent appetite stimulating effects, also stimulates growth hormone release. We hypothesized that altered levels of total ghrelin (TG) or acylated ghrelin (AG) could affect growth by altering growth hormone secretion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf47a12b90ddb8e6d51f849569356e7
https://doi.org/10.1203/pdr.0b013e3182181b2c
https://doi.org/10.1203/pdr.0b013e3182181b2c
Publikováno v:
Otolaryngology–Head and Neck Surgery. 145:476-481
Transforming growth factor-β2 (TGF-β2) is a principal cytokine of interest in the pathogenesis of scar formation and is a potential target for future molecular-based adjunctive therapies. The authors hypothesize that interfering RNA (RNAi) can be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fcbbe6ba8640b41d1f0763c244c7ca
https://doi.org/10.1177/0194599811409534
https://doi.org/10.1177/0194599811409534
Autor:
Peter R. Hoffmann, Gregory J. Fredericks, Hanna J. Osterheld, FuKun W. Hoffmann, Franz M. Hess, Frederic Mercier, Aaron H. Rose
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(46)
Calcium (Ca(2+)) is a secondary messenger in cells and Ca(2+) flux initiated from endoplasmic reticulum (ER) stores via inositol 1,4,5-triphosphate (IP3) binding to the IP3 receptor (IP3R) is particularly important for the activation and function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777fc07fecc8eb690576a6ed07ff1178
https://pubmed.ncbi.nlm.nih.gov/25368151
https://pubmed.ncbi.nlm.nih.gov/25368151
Autor:
Svenja Meiler, Zhi Huang, Yvonne Baumer, Robert L. Norton, FuKun W. Hoffmann, Peter R. Hoffmann, Gregory J. Fredericks, William A. Boisvert, Aaron H. Rose
CD36 requires palimitoylation in a selenoprotein K-dependent manner, to localize lipid rafts and function properly. Selk is an ER transmembrane protein important for calcium flux and macrophage activation, but its role in foam cell formation and athe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1887cce77511329e8a0b96bdce8694
https://europepmc.org/articles/PMC3629442/
https://europepmc.org/articles/PMC3629442/
Publikováno v:
Journal of telemedicine and telecare. 17(5)
We created a website for patients and families that allowed them to review clinic test results, review educational materials related to these results and post questions to their diabetes educator. Fingerstick haemoglobin A1c (HbA1c) testing and perio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456d8ee937945dd782b2a3c5fbbc11eb
https://pubmed.ncbi.nlm.nih.gov/21565846
https://pubmed.ncbi.nlm.nih.gov/21565846