Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gregory J. Fici"'
Autor:
Clay T. Cramer, Brian Goetz, Krista L.M. Hopson, Gregory J. Fici, Rose M. Ackermann, Stephen C. Brown, Charles L. Bisgaier, W.G. Rajeswaran, Daniela C. Oniciu, Michael E. Pape
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 7, Pp 1289-1301 (2004)
We have identified a novel ω-hydroxy-alkanedicarboxylic acid, ESP 55016, that favorably alters serum lipid variables in obese female Zucker (fa/fa) rats. ESP 55016 reduced serum non-HDL-cholesterol (non-HDL-C), triglyceride, and nonesterified fatty
Externí odkaz:
https://doaj.org/article/6e66dc604caa440cad0b2da77bb5ad67
Autor:
Rose Ackermann, Gregory J. Fici, Brian Goetz, Krista L.M. Hopson, Michael E. Pape, Daniela C. Oniciu, Stephen C. Brown, Clay T. Cramer, W.G. Rajeswaran, Charles L. Bisgaier
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 7, Pp 1289-1301 (2004)
We have identified a novel omega-hydroxy-alkanedicarboxylic acid, ESP 55016, that favorably alters serum lipid variables in obese female Zucker (fa/fa) rats. ESP 55016 reduced serum non-HDL-cholesterol (non-HDL-C), triglyceride, and nonesterified fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf00998644f35056543cf27844790a5b
http://www.sciencedirect.com/science/article/pii/S0022227520317855
http://www.sciencedirect.com/science/article/pii/S0022227520317855
Autor:
Wenning Qin, Rongqing Shuang, Gregory J. Fici, Richard L. Myers, Adele M. Pauley, Chai An Mao, Ismail Kola, Jinhe Li, Carol S Himes, Gregory P. Donoho, Jeffrey S. Nye, Kalpana M. Merchant
Publikováno v:
Journal of Biological Chemistry. 278:33445-33449
Nicastrin is a component of the gamma-secretase complex that has been shown to adhere to presenilin-1 (PS1), Notch, and APP. Here we demonstrate that Nicastrin-deficient mice showed a phenotype that is indistinguishable from PS1/PS2 double knock-out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797d2fdb7c28d27a2b593322f6cb603c
https://doi.org/10.1074/jbc.m301288200
https://doi.org/10.1074/jbc.m301288200
Autor:
Thomas T. Kawabe, Karl Kappenman, Roger A. Poorman, Barry S. Lutzke, Dennis E. Epps, Antonio Molinari, Ronald W. Sarver, Allen E. Buhl, Bruce M. Taylor, Gregory J. Fici
Publikováno v:
Journal of Protein Chemistry. 22:31-40
The time dependency of the spontaneous aggregation of the fibrillogenic beta-amyloid peptide, Abeta1-40, was measured by turbidity, circular dichroism, HPLC, and fluorescence polarization. The results by all methods were comparable and they were most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbd06409a74d4cc1d4f1a2d9b233cac
https://doi.org/10.1023/a:1023063626770
https://doi.org/10.1023/a:1023063626770
Autor:
P.F. Von Voigtlander, S.M. Plaisted, C.M. Campbell, Gregory J. Fici, John S. Althaus, F.J. Kezdy, J.G. Hoogerheide
Publikováno v:
Microchemical Journal. 56:155-164
During ischemia, peroxynitrite may be a toxic intermediate which formsin vivowhen nitric oxide condenses with superoxide. Alone, peroxynitrite appears to directly react with aromatic and sulfhydryl nucleophiles. At physiological pH, peroxynitrite rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76ec2b08f5b0d54c67bad64d403d64a
https://doi.org/10.1006/mchj.1996.1444
https://doi.org/10.1006/mchj.1996.1444
Autor:
Andrea J Gonzales, Gregory J. Fici, Michelle Aleo, James E. Messamore, Erin E. McCandless, Catherine Rugg
Publikováno v:
Veterinary immunology and immunopathology. 157(1-2)
The canine cytokine IL-31 induces pruritus in dogs and can be detected in dogs with atopic dermatitis; however very little is understood around its interactions with specific canine cells. We hypothesize that IL-31 is involved in the progression of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b647f6a6a9887c9f20a3772fc4c1e8
https://pubmed.ncbi.nlm.nih.gov/24321252
https://pubmed.ncbi.nlm.nih.gov/24321252
Autor:
Andrea J. Gonzales, William R. Humphrey, James E. Messamore, Timothy J. Fleck, Gregory J. Fici, John A. Shelly, Janet F. Teel, Gary F. Bammert, Steven A. Dunham, Troy E. Fuller, Robert B. McCall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42dd93017adb9f11bad6f9dcd8445c5c
https://doi.org/10.1002/9781118644317.ch7
https://doi.org/10.1002/9781118644317.ch7
Publikováno v:
Pathophysiology and Clinical Applications of Nitric Oxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd2d24e3a4017815b91eaf178cd3d2c
https://doi.org/10.4324/9780203303726_chapter_28
https://doi.org/10.4324/9780203303726_chapter_28
Autor:
Andrew McKee, Lianhao Zhang, Stephen C Brown, Anna Denysenko, Charles L Bisgaier, Gregory J Fici, Tian-Bao Huang, Jean-Louis H Dasseux, Caiming Duan, Brian R. Krause, Brian Goetz, Michael E Pape, Daniela C. Oniciu, Janell M Lutostanski, Ralf Mueller, Narendra Lalwani, Clay T Cramer, Jing Yang, Sandra L Drake, Emil Pop
Publikováno v:
Journal of medicinal chemistry. 49(1)
A series of long (11-15) hydrocarbon chain diols and diacids with various central functional groups and terminal gem-dimethyl or -methyl/aryl substituents was synthesized and evaluated in both in vivo and in vitro assays for its potential to favorabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78ab415baf95911b25d9975eb684bce
https://pubmed.ncbi.nlm.nih.gov/16392818
https://pubmed.ncbi.nlm.nih.gov/16392818
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 312(1)
Recent studies indicating that some nonsteroidal anti-inflammatory drugs (NSAIDs) selectively modulate gamma-secretase cleavage of amyloid precursor protein (APP) while sparing Notch processing have generated interest in discovery of novel gamma-secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6dce937c5d92412e3857659e5f1c1f
https://pubmed.ncbi.nlm.nih.gov/15340006
https://pubmed.ncbi.nlm.nih.gov/15340006