Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Gregory J Morton"'
Autor:
Chelsea L Faber, Jennifer D Deem, Bao Anh Phan, Tammy P Doan, Kayoko Ogimoto, Zaman Mirzadeh, Michael W Schwartz, Gregory J Morton
Publikováno v:
eLife, Vol 10 (2021)
The brain plays an essential role in driving daily rhythms of behavior and metabolism in harmony with environmental light–dark cycles. Within the brain, the dorsomedial hypothalamic nucleus (DMH) has been implicated in the integrative circadian con
Externí odkaz:
https://doaj.org/article/de654672db84412caa24254afde95e76
Autor:
Jennifer D Deem, Chelsea L Faber, Christian Pedersen, Bao Anh Phan, Sarah A Larsen, Kayoko Ogimoto, Jarrell T Nelson, Vincent Damian, Megan A Tran, Richard D Palmiter, Karl J Kaiyala, Jarrad M Scarlett, Michael R Bruchas, Michael W Schwartz, Gregory J Morton
Publikováno v:
eLife, Vol 9 (2020)
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Externí odkaz:
https://doaj.org/article/3bf1e03edc9c473196f7e1c90cbf2a36
Autor:
Katya B Rubinow, Barbara Houston, Shari Wang, Leela Goodspeed, Kayoko Ogimoto, Gregory J Morton, Christopher McCarty, Robert E Braun, Stephanie T Page
Publikováno v:
Asian Journal of Andrology, Vol 20, Iss 3, Pp 276-283 (2018)
Androgen deprivation in men leads to increased adiposity, but the mechanisms underlying androgen regulation of fat mass have not been fully defined. Androgen receptor (AR) is expressed in monocytes/macrophages, which are resident in key metabolic tis
Externí odkaz:
https://doaj.org/article/9a1337f7c38f4243a0f5b086461988fb
Autor:
Sanshiro Tateya, Norma Rizzo-De Leon, Andrew M Cheng, Brian P Dick, Woo Je Lee, Madeleine L Kim, Kevin O'Brien, Gregory J Morton, Michael W Schwartz, Francis Kim
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215601 (2019)
During periods in which glucose absorption from the gastrointestinal (GI) tract is insufficient to meet body requirements, hepatic gluconeogenesis plays a key role to maintain normal blood glucose levels. The current studies investigated the role in
Externí odkaz:
https://doaj.org/article/149227ddf9234b0385ca67ec70389f22
Autor:
Laura J den Hartigh, Shari Wang, Leela Goodspeed, Tomasz Wietecha, Barbara Houston, Mohamed Omer, Kayoko Ogimoto, Savitha Subramanian, G A Nagana Gowda, Kevin D O'Brien, Karl J Kaiyala, Gregory J Morton, Alan Chait
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172912 (2017)
BACKGROUND:Widely used as a weight loss supplement, trans-10,cis-12 conjugated linoleic acid (10,12 CLA) promotes fat loss in obese mice and humans, but has also been associated with insulin resistance. OBJECTIVE:We therefore sought to directly compa
Externí odkaz:
https://doaj.org/article/b68becef00ec4893a2579e0537d569ae
Autor:
Kendra L. Francis, Hengqi B. Zheng, David L. Suskind, Taylor A. Murphree, Bao Anh Phan, Emily Quah, Aarun S. Hendrickson, Xisheng Zhou, Mason Nuding, Alexandra S. Hudson, Miklos Guttman, Gregory J. Morton, Michael W. Schwartz, Kimberly M. Alonge, Jarrad M. Scarlett
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The intestinal extracellular matrix (ECM) helps maintain appropriate tissue barrier function and regulate host-microbial interactions. Chondroitin sulfate- and dermatan sulfate-glycosaminoglycans (CS/DS-GAGs) are integral components of the i
Externí odkaz:
https://doaj.org/article/079a8bfa3048479493c38f401f2d9cdd
Autor:
Thomas H Meek, Gregory J Morton
Publikováno v:
Indian Journal of Endocrinology and Metabolism, Vol 16, Iss 9, Pp 534-542 (2012)
Diabetes is a major worldwide problem. Despite some progress in the development of new antidiabetic agents, the ability to maintain tight glycemic control in order to prevent renal, retinal, and neuropathic complications of diabetes without adverse c
Externí odkaz:
https://doaj.org/article/d84eb90684404a9bb5a89f696e959bbf
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119391 (2015)
Survival of free-living animals depends on the ability to maintain core body temperature in the face of rapid and dramatic changes in their thermal environment. If food intake is not adjusted to meet the changing energy demands associated with change
Externí odkaz:
https://doaj.org/article/69968a4b36d74999925016589ae6bbee
Autor:
Karl J Kaiyala, Gregory J Morton, Joshua P Thaler, Thomas H Meek, Tracy Tylee, Kayoko Ogimoto, Brent E Wisse
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41473 (2012)
Despite the suggestion that reduced energy expenditure may be a key contributor to the obesity pandemic, few studies have tested whether acutely reduced energy expenditure is associated with a compensatory reduction in food intake. The homeostatic me
Externí odkaz:
https://doaj.org/article/725d4cf9f1c340eca7841ee3f951d8a8
Autor:
Allison Wanting Xu, Christopher B Kaelin, Gregory J Morton, Kayoko Ogimoto, Kimber Stanhope, James Graham, Denis G Baskin, Peter Havel, Michael W Schwartz, Gregory S Barsh
Publikováno v:
PLoS Biology, Vol 3, Iss 12, p e415 (2005)
Normal aging in humans and rodents is accompanied by a progressive increase in adiposity. To investigate the role of hypothalamic neuronal circuits in this process, we used a Cre-lox strategy to create mice with specific and progressive degeneration
Externí odkaz:
https://doaj.org/article/4114ec43dfc945be96b9873c0a23960f