Zobrazeno 1 - 10
of 412
pro vyhledávání: '"Gregory J Anderson"'
Autor:
Prashant Sharma, Marie Reichert, Yan Lu, Thomas C Markello, David R Adams, Peter J Steinbach, Brie K Fuqua, Xenia Parisi, Stephen G Kaler, Christopher D Vulpe, Gregory J Anderson, William A Gahl, May Christine V Malicdan
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008143 (2019)
Maintenance of the correct redox status of iron is functionally important for critical biological processes. Multicopper ferroxidases play an important role in oxidizing ferrous iron, released from the cells, into ferric iron, which is subsequently d
Externí odkaz:
https://doaj.org/article/8434e917264b45e197052e868151132b
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171054 (2017)
Iron is crucial for many biological functions, but quantitatively the most important use of iron is in the production of hemoglobin in red blood cell precursors. The amount of iron in the plasma, and hence its availability for hemoglobin synthesis, i
Externí odkaz:
https://doaj.org/article/cb7847de62ca45ed9ada3da3d28e51b3
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184366 (2017)
Hephaestin is a large membrane-anchored multicopper ferroxidase involved in mammalian iron metabolism. Newly absorbed dietary iron is exported across the enterocyte basolateral membrane by the ferrous iron transporter ferroportin, but hephaestin incr
Externí odkaz:
https://doaj.org/article/451cf2643bbb458ab3b918e77e37fcad
Autor:
Brie K Fuqua, Yan Lu, Deepak Darshan, David M Frazer, Sarah J Wilkins, Natalie Wolkow, Austin G Bell, JoAnn Hsu, Catherine C Yu, Huijun Chen, Joshua L Dunaief, Gregory J Anderson, Chris D Vulpe
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98792 (2014)
Hephaestin is a vertebrate multicopper ferroxidase important for the transfer of dietary iron from intestinal cells to the blood. Hephaestin is mutated in the sex-linked anemia mouse, resulting in iron deficiency. However, sex-linked anemia mice stil
Externí odkaz:
https://doaj.org/article/9456e0ed760148cfb4de02d0a7893399
The staminal column in Solanum pollination: important in attraction, essential as a landing platform
Publikováno v:
Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology. 157:632-639
Autor:
Caglar Doguer, Jung-Heun Ha, Sukru Gulec, Chris D. Vulpe, Gregory J. Anderson, James F. Collins
Publikováno v:
Blood Advances, Vol 1, Iss 17, Pp 1335-1346 (2017)
Abstract: Regulation of intestinal iron absorption is crucial to maintain body iron levels because humans have no regulated iron-excretory system. Elucidating molecular events that mediate intestinal iron transport is thus important for the developme
Externí odkaz:
https://doaj.org/article/e6cb35695064469ca33d94537fde9c1c
Autor:
Sheridan L. Helman, Jie Zhou, Brie K. Fuqua, Yan Lu, James F. Collins, Huijun Chen, Christopher D. Vulpe, Gregory J. Anderson, David M. Frazer
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, vol 36, iss 2
Biometals
Biometals
The mammalian multicopper ferroxidases (MCFs) ceruloplasmin (CP), hephaestin (HEPH) and zyklopen (ZP) comprise a family of conserved enzymes that are essential for body iron homeostasis. Each of these enzymes contains six biosynthetically incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b61329225401e190bc038d5c2214ce
https://escholarship.org/uc/item/35n736xd
https://escholarship.org/uc/item/35n736xd
Autor:
Gregory J. Anderson, Sarah J. Wilkins, Daniel R. McKeating, Nuno Faria, Jonathan J. Powell, Anthony V. Perkins, Sheridan L. Helman, David M. Frazer, James S. M. Cuffe, Gunter Hartel
Publikováno v:
The Journal of Nutrition. 152:714-722
BACKGROUND: Many women enter pregnancy with iron stores that are insufficient to maintain maternal iron balance and support fetal development and, consequently, often require iron supplements. However, the side effects associated with many currently
Autor:
Cornel S.G. Mirciov, Sarah J. Wilkins, Grace C. C. Hung, Sheridan L. Helman, Gregory J. Anderson, David M. Frazer
Publikováno v:
Haematologica, Vol 103, Iss 10 (2018)
The stimulation of erythrocyte formation increases the demand for iron by the bone marrow and this in turn may affect the levels of circulating diferric transferrin. As this molecule influences the production of the iron regulatory hormone hepcidin,
Externí odkaz:
https://doaj.org/article/1b11bd582f8140b091bbcf927056e14b
Autor:
Gregory J. Anderson, Xiao Yang, Xudong Wang, Kim Seong Jin, Yinlong Zhang, Yiye Li, Shaoli Liu, Guangjun Nie, Xiao Zhao, Xiaozheng Zhao
Publikováno v:
ACS Nano. 15:14149-14161
Pancreatic ductal adenocarcinoma (PDAC) cells are surrounded by a dense extracellular matrix (ECM), which greatly restricts the access of therapeutic agents, resulting in poor clinical response to chemotherapy. Transforming growth factor-β1 (TGF-β1