Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Gregory I. Giles"'
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 1771-1775 (2018)
Nitric oxide (NO) donor drugs have a range of clinical applications, and are also being developed as therapeutics for the potential treatment of multiple diseases. This article presents data describing the synthesis and characterisation of a novel NO
Externí odkaz:
https://doaj.org/article/2ab48b7af31347d8aceff547ebf1f520
Autor:
Roan A. S. Vasdev, Lachlan F. Gaudin, Dan Preston, Jackmil P. Jogy, Gregory I. Giles, James D. Crowley
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
New bis-quinoline (Lq) and bis-isoquinoline-based (Liq) ligands have been synthesized, along with their respective homoleptic [Pd2(Lq or Liq)4]4+ cages (Cq and Ciq). The ligands and cages were characterized by 1H, 13C and diffusion ordered (DOSY) NMR
Externí odkaz:
https://doaj.org/article/644e7c7a3137413ca340d352ce4fc7ff
Publikováno v:
Nitric oxide : biology and chemistry. 129
Nitric oxide (NO) is a key vasodilatory signalling molecule and NO releasing molecules (NO donors) are being examined as potential treatments for many pathologies. The photoresponsive NO donor tert-dodecane S-nitrosothiol (tDodSNO) has been designed
Autor:
Gregory I. Giles, James D. Crowley, Dan Preston, Samantha M. McNeill, Niroshini M. Giles, Peter P. Jones
Publikováno v:
Chemical Research in Toxicology. 33:1822-1834
[Pd2(hextrz)4]4+ is a quadruply stranded helicate, a novel bio-inorganic complex designed to mimic the structure and function of proteins due to its high stability and supramolecular size. We have ...
Publikováno v:
Pharmaceutical Nanotechnology
Nitric oxide (NO) is a short-lived, endogenously produced, signaling molecule which plays multiple roles in mammalian physiology. Underproduction of NO is associated with several pathological processes; hence a broad range of NO donors have emerged a
Autor:
Dan Preston, Synøve Ø. Scottwell, Heather J. L. Brooks, Quinn V. C. van Hilst, Gregory I. Giles, James A Findlay, James D. Crowley, Roan A. S. Vasdev
Publikováno v:
Asian Journal of Organic Chemistry. 8:496-505
Autor:
Houman Alimoradi, Ansa Thomas, Daniel D B Lyth, Anita Barzegar-Fallah, Siddharth S Matikonda, Allan B Gamble, Gregory I Giles
Publikováno v:
Nanotechnology. 33:195101
Nitric oxide (NO) is an important biological signalling molecule that acts to vasodilate blood vessels and change the permeability of the blood vessel wall. Due to these cardiovascular actions, co-administering NO with a therapeutic could enhance dru
Autor:
Samantha M, McNeill, Niroshini M, Giles, Dan, Preston, Peter P, Jones, James D, Crowley, Gregory I, Giles
Publikováno v:
Chemical research in toxicology. 33(7)
[Pd
Autor:
David A. McMorran, Keith C. Gordon, Gregory I. Giles, Warrick K. C. Lo, Jonathan E. Barnsley, Aidan P. McKay, Dan Preston, James D. Crowley
Publikováno v:
Inorganica Chimica Acta. 446:41-53
The new ligands 3-(3-(2-pyridyl)pyrazol-1-ylmethyl)benzoic acid (L2) and 5-(3-(2-pyridyl)pyrazol-1-ylmethyl)benzene 1,3-dicarboxylic acid (L3) are reported and the synthesis and characterisation of [PdCl2(L)] and [PtCl2(L)] complexes of these and the
Publikováno v:
Biochemical Pharmacology. 104:19-28
Redox active molecules containing organoselenium or organotellurium groups catalyse the oxidation of cellular thiols by hydrogen peroxide and are currently being developed as therapeutic agents. Potentially these synthetic thiol peroxidase (TPx) mimi