Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gregory Handy"'
Autor:
Manoj Kumar, Gregory Handy, Stylianos Kouvaros, Yanjun Zhao, Lovisa Ljungqvist Brinson, Eric Wei, Brandon Bizup, Brent Doiron, Thanos Tzounopoulos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Peripheral sensory organ damage leads to compensatory cortical plasticity that is associated with a remarkable recovery of cortical responses to sound. The precise mechanisms that explain how this plasticity is implemented and distributed ov
Externí odkaz:
https://doaj.org/article/6bd1c884e1c64a5380722f9498c210c4
Autor:
Gregory Handy, Alla Borisyuk
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011290 (2023)
Recent experimental works have implicated astrocytes as a significant cell type underlying several neuronal processes in the mammalian brain, from encoding sensory information to neurological disorders. Despite this progress, it is still unclear how
Externí odkaz:
https://doaj.org/article/3b5eb3f16e674dc3a6c3d18eada50703
Autor:
Destinee A. Aponte, Gregory Handy, Amber M. Kline, Hiroaki Tsukano, Brent Doiron, Hiroyuki K. Kato
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Aponte et al. show that cortical direction selectivity to frequency modulated sounds is shaped by asymmetric signal amplification within recurrent circuits. Optogenetics and network modelling demonstrate that this asymmetry arises due to broad spatia
Externí odkaz:
https://doaj.org/article/0872fd73af1640909e596661814b3190
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006015 (2018)
Many diverse biological systems are described by randomly moving particles that can be captured by traps in their environment. Examples include neurotransmitters diffusing in the synaptic cleft before binding to receptors and prey roaming an environm
Externí odkaz:
https://doaj.org/article/6ebc7c04396240bb9d35990b99485da1
Publikováno v:
Frontiers in Systems Neuroscience, Vol 11 (2017)
Astrocytes are a major cell type in the mammalian brain. They are not electrically excitable, but generate prominent Ca2+ signals related to a wide variety of critical functions. The mechanisms driving these Ca2+ events remain incompletely understood
Externí odkaz:
https://doaj.org/article/a4198f5758ff45f192b6c4082b912f70
Understanding the genesis of shared trial-to-trial variability in neural activity within sensory cortex is critical to uncovering the biological basis of information processing in the brain. Shared variability is often a reflection of the structure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b51d2cc2902badfbf1128d2af3725f8d
https://doi.org/10.1101/2023.04.25.538323
https://doi.org/10.1101/2023.04.25.538323
Autor:
Gregory Handy, Alla Borisyuk
Recent experimental works have implicated astrocytes as a significant cell type underlying several neuronal processes in the mammalian brain, from encoding sensory information to neurological disorders. Despite this progress, it is still unclear how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9147802344b11e479dfb130dc23ac4f
https://doi.org/10.1101/2022.09.26.508928
https://doi.org/10.1101/2022.09.26.508928
Autor:
Ian Antón Oldenburg, William D. Hendricks, Gregory Handy, Kiarash Shamardani, Hayley A. Bounds, Brent Doiron, Hillel Adesnik
Recurrent cortical activity sculpts visual perception by refining, amplifying, or suppressing incoming visual signals. Despite the importance of recurrent circuits for cortical processing, the basic rules that govern how nearby cortical neurons influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58bfe8c77856a3d00e959103b9ff724
https://doi.org/10.1101/2022.09.20.508739
https://doi.org/10.1101/2022.09.20.508739
Autor:
Manoj Kumar, Gregory Handy, Stylianos Kouvaros, Lovisa Ljungqvist Brinson, Brandon Bizup, Brent Doiron, Thanos Tzounopoulos
Peripheral sensory organ damage leads to compensatory cortical plasticity that supports a remarkable recovery of perceptual capabilities. A major knowledge gap is the lack of precise mechanisms that explain how this plasticity is implemented and dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21eefb40f4a0730e337e5c36c01b5f18
https://doi.org/10.1101/2022.09.15.508128
https://doi.org/10.1101/2022.09.15.508128
Publikováno v:
Neuron. 111:405-417.e5
Gamma band synchronization can facilitate local and long-range communication in neural circuits. In the primary visual cortex (V1) the strength of synchronization on the local level is strongly tuned to the contrast, size and center/surround orientat