Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gregory Glenn"'
Autor:
Klara Lenart, Rodrigo Arcoverde Cerveira, Fredrika Hellgren, Sebastian Ols, Daniel J. Sheward, Changil Kim, Alberto Cagigi, Matthew Gagne, Brandon Davis, Daritza Germosen, Vicky Roy, Galit Alter, Hélène Letscher, Jérôme Van Wassenhove, Wesley Gros, Anne-Sophie Gallouët, Roger Le Grand, Harry Kleanthous, Mimi Guebre-Xabier, Ben Murrell, Nita Patel, Gregory Glenn, Gale Smith, Karin Loré
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract The immune responses to Novavax’s licensed NVX-CoV2373 nanoparticle Spike protein vaccine against SARS-CoV-2 remain incompletely understood. Here, we show in rhesus macaques that immunization with Matrix-MTM adjuvanted vaccines predominant
Externí odkaz:
https://doaj.org/article/c088a289c59c484090d22680d31eac78
Autor:
Ying Liu, Ling Ye, Fang Lin, Yasmine Gomaa, David Flyer, Ricardo Carrion, Jean L. Patterson, Mark R. Prausnitz, Gale Smith, Gregory Glenn, Hua Wu, Richard W. Compans, Chinglai Yang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ff2b5d4e8873422293eb5e1c62295876
Autor:
Linda Stertman, Anna-Karin E. Palm, Behdad Zarnegar, Berit Carow, Carolina Lunderius Andersson, Sofia E. Magnusson, Cecilia Carnrot, Vivek Shinde, Gale Smith, Gregory Glenn, Louis Fries, Karin Lövgren Bengtsson
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 1 (2023)
Matrix-M™ adjuvant is a key component of several novel vaccine candidates. The Matrix-M adjuvant consists of two distinct fractions of saponins purified from the Quillaja saponaria Molina tree, combined with cholesterol and phospholipids to form 40
Externí odkaz:
https://doaj.org/article/f73e86e78de8490f9c7688c046ee0852
Autor:
Carolyn Rydyznski Moderbacher, Christina Kim, Jose Mateus, Joyce Plested, Mingzhu Zhu, Shane Cloney-Clark, Daniela Weiskopf, Alessandro Sette, Louis Fries, Gregory Glenn, Shane Crotty
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
NVX-CoV2373 is an adjuvanted recombinant full-length SARS-CoV-2 spike trimer protein vaccine demonstrated to be protective against COVID-19 in efficacy trials. Here we demonstrate that vaccinated individuals made CD4+ T cell responses after 1 and 2 d
Externí odkaz:
https://doaj.org/article/d1bcb00519ff408b99a843d3d67b9a38
Autor:
Jing-Hui Tian, Nita Patel, Robert Haupt, Haixia Zhou, Stuart Weston, Holly Hammond, James Logue, Alyse D. Portnoff, James Norton, Mimi Guebre-Xabier, Bin Zhou, Kelsey Jacobson, Sonia Maciejewski, Rafia Khatoon, Malgorzata Wisniewska, Will Moffitt, Stefanie Kluepfel-Stahl, Betty Ekechukwu, James Papin, Sarathi Boddapati, C. Jason Wong, Pedro A. Piedra, Matthew B. Frieman, Michael J. Massare, Louis Fries, Karin Lövgren Bengtsson, Linda Stertman, Larry Ellingsworth, Gregory Glenn, Gale Smith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Here, the authors characterize a SARS-CoV-2 subunit vaccine candidate that contains full-length spike protein stabilized in its prefusion conformation, and show immunogenicity in baboons and protection in mice with Matrix-M adjuvanted vaccine.
Externí odkaz:
https://doaj.org/article/4a4e382fc93a4e5c84f3c4b94fc40a65
Autor:
Matthew J. Gorman, Nita Patel, Mimi Guebre-Xabier, Alex L. Zhu, Caroline Atyeo, Krista M. Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jr., Jing-Hui Tian, Dansu Yuan, Kathryn A. Bowman, Bin Zhou, Sonia Maciejewski, Marisa E. McGrath, James Logue, Matthew B. Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas A. Lauffenburger, Ann M. Greene, Alyse D. Portnoff, Michael J. Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100405- (2021)
Summary: Recently approved vaccines have shown remarkable efficacy in limiting SARS-CoV-2-associated disease. However, with the variety of vaccines, immunization strategies, and waning antibody titers, defining the correlates of immunity across a spe
Externí odkaz:
https://doaj.org/article/4986517e15404f80baa1ac1f4714b268
Autor:
José L. Román-Moreno, Guadalupe P. Radilla-Serrano, Alejandra Flores-Castro, José De J. Berrios, Gregory Glenn, Areli Salgado-Delgado, Heidi M. Palma-Rodríguez, Apolonio Vargas-Torres
Publikováno v:
Heliyon, Vol 6, Iss 9, Pp e04927- (2020)
Baked foams made with plantain flour (PF) and sugarcane fiber (SF) were characterized by calorimetric, mechanical, physicochemical and structural techniques in order to assess the results induced by different sugarcane concentrations and fiber size o
Externí odkaz:
https://doaj.org/article/c491bba488c34cb29c4bef9f98816421
Autor:
Qingqing Xie, Zhao Wang, Fengyun Ni, Xiaorui Chen, Jianpeng Ma, Nita Patel, Hanxin Lu, Ye Liu, Jing-Hui Tian, David Flyer, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Qinghua Wang
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210749 (2019)
Globally, human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in newborns, young children, and the elderly for which there is no vaccine. The RSV fusion (F) glycoprotein is a major target for vaccine devel
Externí odkaz:
https://doaj.org/article/cfdeb2d3629d4702a3334786e4caba93
Autor:
Gale Smith, Rama Raghunandan, Yingyun Wu, Ye Liu, Michael Massare, Margret Nathan, Bin Zhou, Hanxin Lu, Sarathi Boddapati, Jingning Li, David Flyer, Gregory Glenn
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50852 (2012)
Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and immunocompromised individuals. The lack of a safe and effective RSV vaccine represents a majo
Externí odkaz:
https://doaj.org/article/0a7aca2c825048ba8fb18a9332825bee
Publikováno v:
BMC Microbiology, Vol 9, Iss 1, p 124 (2009)
Abstract Background Variovorax paradoxus is an aerobic soil bacterium frequently associated with important biodegradative processes in nature. Our group has cultivated a mucoid strain of Variovorax paradoxus for study as a model of bacterial developm
Externí odkaz:
https://doaj.org/article/e67894108bca43efbee598c3c100bf43