Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gregory G. Reinholz"'
Autor:
James S. Fitzsimmons, Shawn W. O'Driscoll, Jan C. Schagemann, H. W. Chung, Gregory G. Reinholz, Eike Mrosek
Publikováno v:
Bone & Joint Research
Objectives We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would allow for secure implant fixation, subseque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a9073dad98cec85e690c9c9f8932ca
https://pubmed.ncbi.nlm.nih.gov/27660334
https://pubmed.ncbi.nlm.nih.gov/27660334
Autor:
Shawn W. O'Driscoll, Gregory G. Reinholz, Q. Chen, T.J. Ruesink, A. Olivos-Meza, Michelle E. Casper, James S. Fitzsimmons, Kai Nan An
Publikováno v:
Osteoarthritis and Cartilage. 18:1183-1191
Summary Objective To compare the efficacy of in situ transforming growth factor-beta1 (TGF-β1)-pretreated periosteum to untreated periosteum for regeneration of osteochondral tissue in rabbits. Methods In the pretreatment group, 12 month-old New Zea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9f1dbb74df43d6084d2077a582c98a
https://doi.org/10.1016/j.joca.2010.06.003
https://doi.org/10.1016/j.joca.2010.06.003
Autor:
James S. Fitzsimmons, Gregory G. Reinholz, Fong-Chin Su, Joris Bekkers, Michelle E. Casper, James J. Stone, Yih Wen Tarng, Shawn W. O'Driscoll, Kai Nan An
Publikováno v:
Journal of Biomedical Materials Research Part A. :156-163
The purpose of this study was to investigate the effect of directional fluid flow on periosteal chondrogenesis. Periosteal explants were harvested from 2-month-old rabbits and sutured onto poly-epsilon-caprolactone (PCL) scaffolds with the cambium la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b3dd5063e137818e57dc25c21dcade
https://doi.org/10.1002/jbm.a.32830
https://doi.org/10.1002/jbm.a.32830
Autor:
Harri Lönnberg, Luis Sanchez-Perez, Vivian Negron, David P Sebesta, Shawn Zinnen, Monica M. Reinholz, Diane F. Jelinek, Anthony J. Croatt, Amylou C. Dueck, Leslie M. Jonart, Henry B F Hal Dixon, James N. Ingle, Wilma L. Lingle, Thomas C. Spelsberg, Toshiyuki Yoneda, Gregory G. Reinholz, David Dingli, Kathleen A Kitzmann, Karl A. Nath, Abdalla K Abdalla, Bonnie K. Arendt, Stephen J. Russell, Alexander Karpeisky, Amy K Bruzek
Publikováno v:
Bone. 47:12-22
Despite palliative treatments, tumor-induced bone disease (TIBD) remains highly debilitating for many cancer patients and progression typically results in death within two years. Therefore, more effective therapies with enhanced anti-resorptive and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551b1530cde98df8044875e1157ad4f0
https://doi.org/10.1016/j.bone.2010.03.006
https://doi.org/10.1016/j.bone.2010.03.006
Autor:
T.J. Ruesink, Shawn W. O'Driscoll, James S. Fitzsimmons, Michelle E. Casper, Jan C. Schagemann, H. W. Chung, Gregory G. Reinholz
Publikováno v:
Osteoarthritis and Cartilage. 17:723-734
SummaryObjectiveTo examine the potential for rejuvenation of aged periosteum by local injection of transforming growth factor-beta1 (TGF-β1) and insulin-like growth factor-1 (IGF-1) alone or in combination to induce cambium cell proliferation and en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5be32410afee1e5a9aa323b180ef587
https://doi.org/10.1016/j.joca.2008.10.011
https://doi.org/10.1016/j.joca.2008.10.011
Autor:
James N. Ingle, Marat Ya. Karpeisky, Emily S. Sanders, Nelly Sh. Padyukova, Barbara Getz, Sergey N. Mikhailov, Thomas C. Spelsberg, Gregory G. Reinholz
Publikováno v:
Breast Cancer Research and Treatment. 71:257-268
While the effects of bisphosphonates on bone-resorbing osteoclasts have been well documented, the effects of bisphosphonates on other cell types are not as well studied. Recently, we reported that bisphosphonates have direct effects on bone-forming h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361e964ec34f1ff385f01b55b9d5d021
https://doi.org/10.1023/a:1014418017382
https://doi.org/10.1023/a:1014418017382
Autor:
Jürgen Rohwedel, M. Fehr, Gregory G. Reinholz, Jan Kramer, Solomon F. D. Paul, C. Kaps, Michelle E. Casper, Jan C. Schagemann, H. Mittelstaedt
Publikováno v:
Journal of biomedical materials research. Part A. 101(6)
The objective of this study was to develop a scaffold for mesenchymal stromal cell (MSC) recruitment, proliferation, and chondrogenic differentiation. The concept behind the design is to mimic the cartilage matrix and contain stimulatory agents that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5334b26f58fd8d216303e0ec3fa5363
https://pubmed.ncbi.nlm.nih.gov/23184542
https://pubmed.ncbi.nlm.nih.gov/23184542
Autor:
James S. Fitzsimmons, Mahrokh Dadsetan, Shawn W. O'Driscoll, Jan C. Schagemann, Gregory G. Reinholz, Michelle E. Casper, Eike Mrosek, Haymo Kurz, James S. Stone, Sun Yu-Long
Publikováno v:
Biomaterials. 31(10)
Previously we demonstrated that chondrocyte ECM synthesis and mitotic activity was dependent on scaffold composition when cultured on uncoated PCL scaffolds (pPCL) or PCL composites containing hyaluronan (PCL/HA), chitosan (PCL/CS), fibrin (PCL/F), o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f4be5e82259307dfa3e5d3a65696d3
https://pubmed.ncbi.nlm.nih.gov/20053441
https://pubmed.ncbi.nlm.nih.gov/20053441
Autor:
Monica M. Reinholz, Joseph H. Schwab, Laurie K. Bale, Cheryl A. Conover, Zachary T. Resch, Shawn W. O'Driscoll, Victoria R. Clemens, Carlos Gonzalez, Gregory G. Reinholz, James S. Fitzsimmons, Kiem G. Auw Yang
Publikováno v:
Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 20(2)
Objective Periosteum is involved in bone growth and fracture healing and has been used as a cell source and tissue graft for tissue engineering and orthopedic reconstruction including joint resurfacing. Periosteum can be induced by transforming growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc3cd6e6251ca957fddd7c47251c7e0
https://pubmed.ncbi.nlm.nih.gov/19656700
https://pubmed.ncbi.nlm.nih.gov/19656700
Autor:
H. W. Chung, Jan C. Schagemann, James S. Fitzsimmons, Shawn W. O'Driscoll, Gregory G. Reinholz, James J. Stone, Eike Mrosek
Publikováno v:
Journal of Biomedical Materials Research Part A.
The aim of this study was to determine the suitability of hybrid scaffolds composed of naturally derived biopolymer gels and macroporous poly-ϵ-caprolactone (PCL) scaffolds for neocartilage formation in vitro. Rabbit articular chondrocytes were seed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b85c7b743122c0d5552ef33b325cad
https://doi.org/10.1002/jbm.a.32521
https://doi.org/10.1002/jbm.a.32521