Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Gregory G. Martin"'
Autor:
Avery L. McIntosh, Gregory G. Martin, Huan Huang, Danilo Landrock, Ann B. Kier, Friedhelm Schroeder
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 646-657 (2018)
Phytocannabinoids, such as Δ9-tetrahydrocannabinol (THC), bind and activate cannabinoid (CB) receptors, thereby “piggy-backing” on the same pathway's endogenous endocannabinoids (ECs). The recent discovery that liver fatty acid binding protein-1
Externí odkaz:
https://doaj.org/article/2b684a0b785240538675786461d2d607
Autor:
Gregory G. Martin, Danilo Landrock, Sarah Chung, Lawrence J. Dangott, Avery L. McIntosh, John T. Mackie, Ann B. Kier, Friedhelm Schroeder
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 11, Pp 2114-2126 (2017)
Upregulation of the hepatic endocannabinoid (EC) receptor [cannabinoid receptor-1 (CB1)] and arachidonoylethanolamide (AEA) is associated with nonalcoholic fatty liver disease (NAFLD). Male mice fed high-fat diet (HFD) ad libitum also exhibit NAFLD,
Externí odkaz:
https://doaj.org/article/2d084cd592f74efcb0fcf2e6cab39446
Autor:
Stephen M. Storey, Huan Huang, Avery L. McIntosh, Gregory G. Martin, Ann B. Kier, Friedhelm Schroeder
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1153-1165 (2017)
Studies in vitro have suggested that both sterol carrier protein-2/sterol carrier protein-x (Scp-2/Scp-x) and liver fatty acid binding protein [Fabp1 (L-FABP)] gene products facilitate hepatic uptake and metabolism of lipotoxic dietary phytol. Howeve
Externí odkaz:
https://doaj.org/article/d627fef73bff4b6ea4c6d613579f8720
Autor:
Avery L. McIntosh, Barbara P. Atshaves, Stephen M. Storey, Kerstin K. Landrock, Danilo Landrock, Gregory G. Martin, Ann B. Kier, Friedhelm Schroeder
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 3, Pp 467-480 (2012)
Although lipid-rich microdomains of hepatocyte plasma membranes serve as the major scaffolding regions for cholesterol transport proteins important in cholesterol disposition, little is known regarding intracellular factors regulating cholesterol dis
Externí odkaz:
https://doaj.org/article/eb28740efce2411a8700e8aed2e6ee3f
Autor:
Barbara P. Atshaves, Avery L. McIntosh, Gregory G. Martin, Danilo Landrock, H. Ross Payne, Shivaprasad Bhuvanendran, Kerstin K. Landrock, Olga I. Lyuksyutova, Jeffery D. Johnson, Ronald D. Macfarlane, Ann B. Kier, Friedhelm Schroeder
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 7, Pp 1429-1447 (2009)
Although in vitro studies suggest a role for sterol carrier protein-2 (SCP-2) in cholesterol trafficking and metabolism, the physiological significance of these observations remains unclear. This issue was addressed by examining the response of mice
Externí odkaz:
https://doaj.org/article/8268f9dd41e145acb5d331de96aebdbb
Autor:
Huan Huang, Avery L. McIntosh, Gregory G. Martin, Anca D. Petrescu, Kerstin K. Landrock, Danilo Landrock, Ann B. Kier, Friedhelm Schroeder
Publikováno v:
PPAR Research, Vol 2013 (2013)
While TOFA (acetyl CoA carboxylase inhibitor) and C75 (fatty acid synthase inhibitor) prevent lipid accumulation by inhibiting fatty acid synthesis, the mechanism of action is not simply accounted for by inhibition of the enzymes alone. Liver fatty a
Externí odkaz:
https://doaj.org/article/03843b8ce0c74258acc30041501f3f1c
Autor:
Kumaravel Mohankumar, Keshav Karki, Rupesh Shrestha, Gregory G. Martin, Stephen Safe, Abigail Schoeller
Publikováno v:
Cancers, Vol 13, Iss 2682, p 2682 (2021)
Cancers
Volume 13
Issue 11
Cancers
Volume 13
Issue 11
Nuclear receptor 4A1 (NR4A1, Nur77, TR3) is more highly expressed in breast and solid tumors compared to non-tumor tissues and is a pro-oncogenic factor in solid tumor-derived cancers. NR4A1 regulates cancer cell growth, survival, migration, and inva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75b5aba1bbe1f5480aa6450617851ba
https://www.mdpi.com/2072-6694/13/11/2682
https://www.mdpi.com/2072-6694/13/11/2682
Autor:
Gregory G. Martin, Friedhelm Schroeder, Huan Huang, Avery L. McIntosh, Ann B. Kier, Lawrence J. Dangott
Publikováno v:
Biochemistry. 57:6027-6042
Although serum Δ9-tetrahydrocannabinol (Δ9-THC) undergoes rapid hepatic clearance and metabolism, almost nothing is known regarding the mechanism(s) whereby this highly lipophilic phytocannabinoid is transported for metabolism/excretion. A novel NB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009c62b5db74ead12ed1cc0fd31699af
https://doi.org/10.1021/acs.biochem.8b00744
https://doi.org/10.1021/acs.biochem.8b00744
Autor:
Friedhelm Schroeder, Mikhail Y. Golovko, Ann B. Kier, Gregory G. Martin, Danilo Landrock, Drew R. Seeger, Sarah Chung, Sherrelle Milligan, Eric J. Murphy, Avery L. McIntosh, Lawrence J. Dangott
Publikováno v:
Archives of Biochemistry and Biophysics. 650:93-102
Dysregulation of the hepatic endocannabinoid (EC) system and high fat diet (HFD) are associated with non-alcoholic fatty liver disease. Liver cytosol contains high levels of two novel endocannabinoid binding proteins-liver fatty acid binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaaf679743980e13f71b153f5202a26
https://doi.org/10.1016/j.abb.2018.05.013
https://doi.org/10.1016/j.abb.2018.05.013
Autor:
Huan Huang, Friedhelm Schroeder, Ann B. Kier, Avery L. McIntosh, Danilo Landrock, Gregory G. Martin
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 646-657 (2018)
Phytocannabinoids, such as Δ9-tetrahydrocannabinol (THC), bind and activate cannabinoid (CB) receptors, thereby "piggy-backing" on the same pathway's endogenous endocannabinoids (ECs). The recent discovery that liver fatty acid binding protein-1 (FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f0e6ea3f3cd865082574f32f5a5c46
http://www.sciencedirect.com/science/article/pii/S002222752033916X
http://www.sciencedirect.com/science/article/pii/S002222752033916X