Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gregory G. Mahairas"'
Autor:
Kassandra S. Thomson, PhD, Guy L. Odom, PhD, Charles E. Murry, MD, PhD, Gregory G. Mahairas, PhD, Farid Moussavi-Harami, MD, Sam L. Teichman, MD, Xiaolan Chen, PhD, Stephen D. Hauschka, PhD, Jeffrey S. Chamberlain, PhD, Michael Regnier, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 666-679 (2016)
Despite recent advances, chronic heart failure remains a significant and growing unmet medical need, reaching epidemic proportions carrying substantial morbidity, mortality, and costs. A safe and convenient therapeutic agent that produces sustained i
Externí odkaz:
https://doaj.org/article/d156eb416a674b9bb2f4b5a526ecf031
Autor:
Jeffrey S. Chamberlain, Charles E. Murry, Gregory G. Mahairas, Sam L. Teichman, Guy L. Odom, Farid Moussavi-Harami, Stephen D. Hauschka, Kassandra S. Thomson, Xiaolan Chen, Michael Regnier
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 666-679 (2016)
Summary Despite recent advances, chronic heart failure remains a significant and growing unmet medical need, reaching epidemic proportions carrying substantial morbidity, mortality, and costs. A safe and convenient therapeutic agent that produces sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691ca22994e9dd83baec522dbf42f3ed
Autor:
Sarah G. Nowakowski, Farid Moussavi-Harami, Hans Reinecke, Stephen C. Kolwicz, Charles E. Murry, Stephen D. Hauschka, Gregory G. Mahairas, Michael Regnier, Xiaolan Chen, Guy L. Odom
Publikováno v:
Molecular Therapy. 24(2):240-250
Impaired systolic function, resulting from acute injury or congenital defects, leads to cardiac complications and heart failure. Current therapies slow disease progression but do not rescue cardiac function. We previously reported that elevating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9339a1ba2638735b55ae8ea8cd0d0b7c
Autor:
Christine M. Posavad, Lawrence Corey, Sita Awasthi, Harvey M. Friedman, Carolyn E. Shaw, Meei Li Huang, David M. Koelle, Gregory G. Mahairas
Publikováno v:
Journal of Virology. 89:8497-8509
We evaluated a genital herpes prophylactic vaccine containing herpes simplex virus 2 (HSV-2) glycoproteins C (gC2) and D (gD2) to stimulate humoral immunity and U L 19 (capsid protein VP5) and U L 47 (tegument protein VP13/14) as T cell immunogens. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bc1c5b2653b74c6fd05083c73904ed
https://doi.org/10.1128/jvi.01089-15
https://doi.org/10.1128/jvi.01089-15
Autor:
Hans Reinecke, Michael A. Laflamme, John Carey, James Leggett, Gregory G. Mahairas, Michael Regnier, Sam L. Teichman, Shin Kadota, Charles E. Murry
Publikováno v:
European Journal of Heart Failure. 17:772-781
Heart failure remains a leading cause of morbidity, hospitalizations, and deaths. We previously showed that overexpression of the enzyme ribonucleotide reductase (RNR) in cardiomyocytes increased levels of the myosin activator, 2-deoxy-ATP, catalysed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::047f356079b1b5b5d5b76f04e2c9482c
https://doi.org/10.1002/ejhf.270
https://doi.org/10.1002/ejhf.270
Autor:
Barbara J. Cleary, Melissa L. Madsen, Gregory G. Mahairas, Steven Swartzell, Elliot J. Lefkowitz, F. Chris Minion
Publikováno v:
Journal of Bacteriology. 186:7123-7133
We present the complete genome sequence of Mycoplasma hyopneumoniae , an important member of the porcine respiratory disease complex. The genome is composed of 892,758 bp and has an average G+C content of 28.6 mol%. There are 692 predicted protein co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e4aba3fa7e3d445c622f213a7d80a3
https://doi.org/10.1128/jb.186.21.7123-7133.2004
https://doi.org/10.1128/jb.186.21.7123-7133.2004
Autor:
Lisa Kim, Travis D. Lorentzen, Pascale Quignon, Francis Galibert, Christophe Hitte, Heidi G. Parker, Richard Guyon, Elaine A. Ostrander, Hawkins B. DeFrance, Corinne Renier, Boris Gelfenbeyn, Françoise Vignaux, Jennifer K. Lowe, Edouard Cadieu, Stéphanie Gloux, Gregory G. Mahairas, Catherine André
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5296-5301
The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the establishment of a unique resource for dissecting the genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943ca8c083cd9b78cc5a3b3c05a70290
https://doi.org/10.1073/pnas.0831002100
https://doi.org/10.1073/pnas.0831002100
Publikováno v:
Infection and Immunity. 71:2239-2243
TheMycobacterium tuberculosisprotein ESAT-6 has unusual immune stimulating activities, has been implicated in the recall of long-lived immunity, and induces protection against tuberculosis in mice. For many diseases caused by bacterial or viral patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af03b6eb03121a090eeba8d47f74b7a6
https://doi.org/10.1128/iai.71.4.2239-2243.2003
https://doi.org/10.1128/iai.71.4.2239-2243.2003
Publikováno v:
Journal of Interferon & Cytokine Research. 22:807-813
Type 1 immune responses play an important role in the resolution of diseases with infectious or oncogenic etiologies. Vaccines for production animals frequently target humoral immune responses and are often ineffective in protecting against disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b38747304e6c60722c6efb26f3e873
https://doi.org/10.1089/107999002320271404
https://doi.org/10.1089/107999002320271404