Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Gregory G Freund"'
Autor:
Stephen J Gainey, Gavin P Horn, Albert E Towers, Maci L Oelschlager, Vincent L Tir, Jenny Drnevich, Kenneth W Fent, Stephen Kerber, Denise L Smith, Gregory G Freund
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201830 (2018)
Firefighting activities appear to increase the risk of acute and chronic lung disease, including malignancy. While self-contained breathing apparatuses (SCBA) mitigate exposures to inhalable asphyxiates and carcinogens, firefighters frequently remove
Externí odkaz:
https://doaj.org/article/6b188fba3a6f4d1cbb873b5f322e66eb
Autor:
jenifer j joesting, morgan l moon, stephan j gainey, brittany l tisza, Neil A Blevins, Gregory G Freund
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Objective: Weight loss is a near societal obsession and many diet programs use significant calorie restriction (CR) including fasting/short term starvation to generate rapid effects. Fasting is also a well-recognized cause of immunosuppression especi
Externí odkaz:
https://doaj.org/article/5ed412f422674bfe8fbdcd2036bcaa76
Autor:
Christopher B Guest, Eric L Deszo, Matthew E Hartman, Jason M York, Keith W Kelley, Gregory G Freund
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1606 (2008)
Macrophages are capable of assuming numerous phenotypes in order to adapt to endogenous and exogenous challenges but many of the factors that regulate this process are still unknown. We report that Ca(2+)/calmodulin-dependent kinase kinase alpha (CaM
Externí odkaz:
https://doaj.org/article/5ed74206df734e87b0b4d31a68fd22d4
Autor:
Christopher B Guest, Matthew E Hartman, Jason C O'Connor, Kenneth S Chakour, Ali A Sovari, Gregory G Freund
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e511 (2007)
Type 2 diabetes (T2D) is associated with accelerated atherosclerosis, which accounts for approximately 75% of all diabetes-related deaths. Here we investigate the link between diabetes and macrophage cholesteryl ester accumulation. When diabetic (db/
Externí odkaz:
https://doaj.org/article/3850c5e0fc0142c48ef03eaa8dd687db
Autor:
Gregory G. Freund, Robert H. McCusker, Alexandra K. Brooks, Andrew J. Steelman, Albert E. Towers, M. Juda
Publikováno v:
Epilepsia. 60:626-635
OBJECTIVE Viral encephalitis increases the risk for developing seizures and epilepsy. Indoleamine 2,3-dioxygenase 1 (Ido1) is induced by inflammatory cytokines and functions to metabolize tryptophan to kynurenine. Kynurenine can be further metabolize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38904b817a5a9ed341bb3acf08867a88
https://doi.org/10.1111/epi.14675
https://doi.org/10.1111/epi.14675
Autor:
Denise L. Smith, Gavin P. Horn, Steven J. Petruzzello, Gregory G. Freund, Samuel I. Bloom, Bo Fernhall
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 4; Pages: 2124
While the fire service has long been a male-dominated occupation, women’s participation in this strenuous, high risk, high performance activity has increased in recent years. Firefighting induces significant cardiovascular strain, including hemosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0a0653028c34a134cab84aeccf9ad1
https://doi.org/10.3390/ijerph19042124
https://doi.org/10.3390/ijerph19042124
Autor:
Julie K. Bray, Gregory G. Freund, Robyn Wall, Albert E. Towers, Leslie Klis McNeil, Gabriel Sean-Hang Chiu, Morgan L. Moon
Publikováno v:
Nutrition & Metabolism, Vol 15, Iss 1, Pp 1-10 (2018)
Nutrition & metabolism, 15:55
Nutrition & Metabolism
Nutrition & metabolism, 15:55
Nutrition & Metabolism
Background Reducing caloric intake is a proven intervention for mitigating and modulating morbidities associated with overnutrition. Caloric restriction is difficult to affect clinically, therefore, dietary interventions that ameliorate the adverse c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ed0501750feb5eb6fb2df1d2b9bc86
http://link.springer.com/article/10.1186/s12986-018-0294-7
http://link.springer.com/article/10.1186/s12986-018-0294-7
Autor:
Keith W. Kelley, Gregory G. Freund, Megan Carson Sulzer, Carlos R. Dostal, Robert H. McCusker
Publikováno v:
Neurobiology of Stress, Vol 7, Iss, Pp 1-15 (2017)
Stressors activate the hypothalamic-pituitary-adrenal (HPA) axis and immune system eliciting changes in cognitive function, mood and anxiety. An important link between stress and altered behavior is stimulation of the Kynurenine Pathway which generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f3e7d08664e02d6bac408bffe0b9eb
http://www.sciencedirect.com/science/article/pii/S2352289516300492
http://www.sciencedirect.com/science/article/pii/S2352289516300492
Autor:
Gregory G. Freund, Albert E. Towers, Steven A. Krauklis, M.L. Oelschlager, Stephen J. Gainey, Robert H. McCusker, Madelyn Lorenz
Publikováno v:
Brain Behav Immun
Acute stressors can induce fear and physiologic responses that prepare the body to protect from danger. A key component of this response is immune system readiness. In particular, inflammasome activation appears critical to linking stress to the immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6485d09a5844172e6b2c379d313171b6
https://europepmc.org/articles/PMC6664453/
https://europepmc.org/articles/PMC6664453/
Autor:
Albert E. Towers, Gregory G. Freund
Publikováno v:
Curr Opin Behav Sci
Psychoneuroimmunology (PNI) aims to elucidate mechanisms by which the immune system can influence behavior. Given the complexity of the brain, studies using inbred rodents have shed critical insight into the presumed vagaries of the human condition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f08b0627429cd080c4422ba221a7b5
https://europepmc.org/articles/PMC6820983/
https://europepmc.org/articles/PMC6820983/